Saffron may have a beneficial effect on various aspects of cardiovascular health and metabolic health. Still, the research is mixed, and studies have included a wide range of patient populations, doses, and formulations (e.g., saffron extract, whole saffron powder, isolated crocin), which makes it difficult to draw any clear conclusions.
Some evidence suggests that saffron can affect lipid profiles, including reductions in triglycerides, total cholesterol, and low-density lipoprotein (LDL) cholesterol. However, this effect may not be observed when it matters most: in people with elevated lipid levels or type 2 diabetes.[1][2]
Saffron may improve glycemic control, with some research finding reductions in both hemoglobin A1c (HbA1c) and fasting glucose, including in people with type 2 diabetes.[1][2]
Saffron might reduce blood pressure, but most research that finds a reduction in systolic blood pressure has found no change in diastolic blood pressure.[1][2]
References
- ^Mohammad Zamani, Mahtab Zarei, Mahlagha Nikbaf-Shandiz, Fatemeh Gholami, Amir Mehdi Hosseini, Maryam Nadery, Farideh Shiraseb, Omid AsbaghiThe effects of saffron supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysisFront Nutr.(2022 Dec 8)
- ^Amatto PPG, Chaves L, Braga GG, Carmona F, Pereira AMSEffect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.J Ethnopharmacol.(2023-Sep-29)