Diabetic Neuropathy

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•Last Updated: November 20, 2025

Diabetic neuropathy is damage to nerves and blood vessels caused by high blood glucose in diabetes. Damage to nerves can cause numbness in the hands, legs, and feet, urinary problems, sexual dysfunction, dizziness, and sharp, burning, or tingling sensations.

Written by:

Fact-checked by:

Last Updated:November 20, 2025

Research Snapshot

27 references on this page

2,156 participants in 7 trials and 1 meta-analysis

Examine Evidence Grades

BDiabetic Neuropathy Symptoms

C9 outcomes

D9 outcomes

Overview

What is diabetic neuropathy?

What are the main signs and symptoms of diabetic neuropathy?

How is diabetic neuropathy diagnosed?

What are some of the main medical treatments for diabetic neuropathy?

Have any supplements been studied for diabetic neuropathy?

How could diet affect diabetic neuropathy?

Are there any other treatments for diabetic neuropathy?

What causes diabetic neuropathy?

Examine Database: Diabetic Neuropathy

Intervention	Health Outcome	Evidence
Alpha-Lipoic Acid	4 outcomes	6 Studies
Cannabis	2 outcomes	3 Studies
Benfotiamine	2 outcomes	1 Study
Ginkgo Biloba	5 outcomes	1 Study
L-Carnitine	3 outcomes	1 Study
Sulbutiamine	3 outcomes	1 Study