Have any supplements been studied for diabetic neuropathy?

•Last Updated: October 25, 2023

Yes, research has examined the effects of several supplements on diabetic neuropathy. These include vitamin D, vitamin B12, L-carnitine, alpha-lipoic acid (ALA), and more.^[1]^[2]^[3]^[4]^[5]^[6] However, additional high-quality randomized controlled trials are needed to make firm conclusions concerning the effectiveness of supplements in reducing the risk of diabetic neuropathy or relieving its symptoms (e.g., pain).

Last Updated:October 25, 2023

References

^Yammine K, Wehbe R, Assi CA systematic review on the efficacy of vitamin D supplementation on diabetic peripheral neuropathy.Clin Nutr.(2020-10)
^Farah S, Yammine KA systematic review on the efficacy of vitamin B supplementation on diabetic peripheral neuropathy.Nutr Rev.(2022-04-08)
^Jayabalan B, Low LLVitamin B supplementation for diabetic peripheral neuropathy.Singapore Med J.(2016-Feb)
^Khalil H, Ang CD, Khalil VVitamin B for treating diabetic peripheral neuropathy - A systematic review.Diabetes Metab Syndr.(2021)
^Rolim LC, da Silva EM, Flumignan RL, Abreu MM, Dib SAAcetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.Cochrane Database Syst Rev.(2019-06-15)
^Abubaker SA, Alonazy AM, Abdulrahman AEffect of Alpha-Lipoic Acid in the Treatment of Diabetic Neuropathy: A Systematic Review.Cureus.(2022-Jun)