Artichoke extract has shown some benefits for cardiovascular measures, particularly in terms of blood lipid improvements. Reductions in total cholesterol are most frequently reported in clinical studies that used artichoke juice (20 mL per day) and leaf extract (50–2,700 mg per day) over durations of 4–12 weeks.[1][2][3][4][5][6][7] Some of these studies also report reductions in triglycerides and/or LDL cholesterol levels with the use of artichoke leaf extract.[1][2][3][5][6][8][6]
Though artichoke leaf extract (50–2,700 mg per day over 4–12 weeks) hasn’t shown an effect on blood pressure in a general population, it has been reported to reduce systolic blood pressure in adults with high blood pressure.[9][10][2] Furthermore, frozen artichoke juice (20 mL per day for 6 weeks) improved endothelial function in individuals with high cholesterol in one study.[5]