The main supplements recommended for celiac disease are micronutrients, since damage to the small intestinal reduces their absorption. Deficiencies in vitamin B6, vitamin B12, iron, folic acid, vitamin D, copper, zinc, and magnesium are common in people with celiac disease.[1] Gluten-free foods also tend to provide lower levels of magnesium, possibly warranting supplementation if insufficient levels are obtained through the diet after small intestinal damage has healed.[2] Probiotics have also been studied, since celiac disease is associated with changes in the gut microbiome.[3] Omega-3 fatty acid supplements have additionally been researched for their ability to reduce inflammation in celiac disease.[4]
Have any supplements been studied for celiac disease?
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•Last Updated: May 16, 2025
Micronutrient supplements are recommended for people with celiac disease due to common deficiencies in vitamins and minerals caused by reduced absorption in the small intestine. Additionally, probiotics and omega-3 fatty acids have been studied for their potential benefits related to gut health and inflammation in celiac disease.