What supplements affect GLP-1 levels?

    Written by:
    Gregory Lopez

    Fact-checked

    by:

    Nick Milazzo
    Last Updated: May 16, 2025

    Some supplements — including yerba mate tea, Momordica charantia extract, berberine, resveratrol, curcumin, and ginseng — have shown the potential to boost GLP-1 levels in preliminary studies. However, randomized controlled trials have generally found that supplements like green tea extract and resveratrol do not increase GLP-1 levels.

    A small handful of test tube and animal studies suggest that supplements such as yerba mate tea,[1] Momordica charantia extract,[2] berberine,[3] resveratrol,[4] curcumin,[5][6] and Ginseng[7][8] could boost GLP-1 levels.

    However, the few randomized controlled trials that have looked at supplements’ impact on GLP-1 have yielded negative results: Green tea extract,[9] resveratrol,[10] and green-plant membranes[11] all don’t seem to boost GLP-1 levels.