Supplements of the greatest interest for liver health include antioxidants like vitamin E and glutathione, polyphenols like resveratrol and curcumin, omega-3 fatty acids, and milk thistle.[1][2] There are also a number of dietary supplements that have been associated with liver damage, such as pyrrolizidine alkaloid-containing herbs, kratom, large doses of green tea extract, kava kava, black cohosh, and Garcinia cambogia.[3] The dosages at which these supplements reach hepatotoxic levels are unknown, and therefore, avoiding formulations that contain one or more of these ingredients can help to support liver health.
Which supplements are of most interest for liver health?
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•Last Updated: May 16, 2025
Key supplements that are beneficial for liver health include antioxidants like vitamin E and glutathione, polyphenols such as resveratrol and curcumin, omega-3 fatty acids, and milk thistle. Conversely, certain supplements like kratom and large doses of green tea extract may cause liver damage, so it's advisable to avoid them.