Examine Database: Alzheimer's Disease Symptoms
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Traditional Chinese Medicine: An effective add-on therapy for treating Alzheimer’s disease?
In this meta-analysis, combining Acorus tatarinowii and Polygala tenuifolia (two herbs of traditional Chinese medicine) alongside conventional drugs improved cognition and functioning in Chinese older adults with Alzheimer's disease more effectively than conventional drugs alone.
Dental health and hippocampal atrophy
Examine Database References
- Saffron - Akhondzadeh S, Sabet MS, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SSh, Yousefi MH, Alimardani R, Jamshidi A, Zare F, Moradi ASaffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, randomized and placebo-controlled trialJ Clin Pharm Ther.(2010 Oct)
- Bacopa Monnieri - Sudesh Prabhakar, Venugopalan Y Vishnu, Manish Modi, Manju Mohanty, Anchal Sharma, Bikas Medhi, B R Mittal, Niranjan Khandelwal, Manoj K Goyal, Vivek Lal, Rajesh Singla, Avinash Kansal, Ajit AvasthiEfficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b StudyAnn Indian Acad Neurol.(Nov-Dec 2020)
- Saffron - Mehdi Farokhnia, Mehdi Shafiee Sabet, Negar Iranpour, Amirhossein Gougol, Habibeh Yekehtaz, Roozbeh Alimardani, Farzaneh Farsad, Maryam Kamalipour, Shahin AkhondzadehComparing the efficacy and safety of Crocus sativus L. with memantine in patients with moderate to severe Alzheimer's disease: a double-blind randomized clinical trialHum Psychopharmacol.(2014 Jul)
- Inositol - Salloway S, Sperling R, Keren R, Porsteinsson AP, van Dyck CH, Tariot PN, Gilman S, Arnold D, Abushakra S, Hernandez C, Crans G, Liang E, Quinn G, Bairu M, Pastrak A, Cedarbaum JM, ELND005-AD201 InvestigatorsA phase 2 randomized trial of ELND005, scyllo-inositol, in mild to moderate Alzheimer diseaseNeurology.(2011 Sep 27)
- Ginkgo Biloba - Herrschaft H, Nacu A, Likhachev S, Sholomov I, Hoerr R, Schlaefke SGinkgo biloba extract EGb 761® in dementia with neuropsychiatric features: a randomised, placebo-controlled trial to confirm the efficacy and safety of a daily dose of 240 mgJ Psychiatr Res.(2012 Jun)
- Panax Ginseng (Korean Ginseng) - Soon-Tae Lee, Kon Chu, Ji-Young Sim, Jae-Hyeok Heo, Manho KimPanax ginseng enhances cognitive performance in Alzheimer diseaseAlzheimer Dis Assoc Disord.(Jul-Sep 2008)
- Alpha-GPC - De Jesus Moreno Moreno MCognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trialClin Ther.(2003 Jan)
- Ginkgo Biloba - Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AFA placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group.JAMA.(1997)
- Panax Ginseng (Korean Ginseng) - Jae-Hyeok Heo, Soon-Tae Lee, Kon Chu, Min Jung Oh, Hyun-Jung Park, Ji-Young Shim, Manho KimHeat-processed ginseng enhances the cognitive function in patients with moderately severe Alzheimer's diseaseNutr Neurosci.(2012 Nov)
- Panax Ginseng (Korean Ginseng) - Jae-Hyeok Heo, Soon-Tae Lee, Min Jung Oh, Hyun-Jung Park, Ji-Young Shim, Kon Chu, Manho KimImprovement of cognitive deficit in Alzheimer's disease patients by long term treatment with korean red ginsengJ Ginseng Res.(2011 Nov)
- Panax Ginseng (Korean Ginseng) - Lee, Soon-Tae., Chu, Kon., Kim, Jeong-Min., Park, Hyun-Jeong., Kim, Man-Ho Cognitive improvement by ginseng in Alzheimer's diseaseJournal of Ginseng Research.()
- Ginkgo Biloba - Kanowski S, Herrmann WM, Stephan K, Wierich W, Hörr RProof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementiaPharmacopsychiatry.(1996 Mar)
- Ginkgo Biloba - Napryeyenko O, Borzenko I; GINDEM-NP Study GroupGinkgo biloba special extract in dementia with neuropsychiatric features. A randomised, placebo-controlled, double-blind clinical trialArzneimittelforschung.(2007)
- Lion's Mane - I-Chen Li, Han-Hsin Chang, Chuan-Han Lin, Wan-Ping Chen, Tsung-Han Lu, Li-Ya Lee, Yu-Wen Chen, Yen-Po Chen, Chin-Chu Chen, David Pei-Cheng LinPrevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled StudyFront Aging Neurosci.(2020 Jun 3)
- Vitamin E - Dysken MW, Sano M, Asthana S, Vertrees JE, Pallaki M, Llorente M, Love S, Schellenberg GD, McCarten JR, Malphurs J, Prieto S, Chen P, Loreck DJ, Trapp G, Bakshi RS, Mintzer JE, Heidebrink JL, Vidal-Cardona A, Arroyo LM, Cruz AR, Zachariah S, Kowall NW, Chopra MP, Craft S, Thielke S, Turvey CL, Woodman C, Monnell KA, Gordon K, Tomaska J, Segal Y, Peduzzi PN, Guarino PDEffect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trialJAMA.(2014 Jan 1)
- Ginkgo Biloba - Ihl R, Tribanek M, Bachinskaya N, GOTADAY Study GroupEfficacy and tolerability of a once daily formulation of Ginkgo biloba extract EGb 761® in Alzheimer's disease and vascular dementia: results from a randomised controlled trialPharmacopsychiatry.(2012 Mar)
- Inositol - Barak Y, Levine J, Glasman A, Elizur A, Belmaker RHInositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trialProg Neuropsychopharmacol Biol Psychiatry.(1996 May)
- Fish Oil - Quinn JF, Raman R, Thomas RG, Yurko-Mauro K, Nelson EB, Van Dyck C, Galvin JE, Emond J, Jack CR Jr, Weiner M, Shinto L, Aisen PSDocosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trialJAMA.(2010 Nov 3)
- Vitamin E - Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJA controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative StudyN Engl J Med.(1997 Apr 24)
- Vitamin D - Jingya Jia, Jing Hu, Xiaoxu Huo, Rujuan Miao, Yanping Zhang, Fei MaEffects of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer's disease: a randomised, double-blind, placebo-controlled trialJ Neurol Neurosurg Psychiatry.(2019 Dec)
- Saffron - Akhondzadeh S, Shafiee Sabet M, Harirchian MH, Togha M, Cheraghmakani H, Razeghi S, Hejazi SS, Yousefi MH, Alimardani R, Jamshidi A, Rezazadeh SA, Yousefi A, Zare F, Moradi A, Vossoughi AA 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's diseasePsychopharmacology (Berl).(2010 Jan)
- Oxiracetam - Green RC, Goldstein FC, Auchus AP, Presley R, Clark WS, Van Tuyl L, Green J, Hersch SM, Karp HRTreatment trial of oxiracetam in Alzheimer's diseaseArch Neurol.(1992 Nov)
- Melatonin - Dewan Md Sumsuzzman, Jeonghyun Choi, Yunho Jin, Yonggeun HongNeurocognitive effects of melatonin treatment in healthy adults and individuals with Alzheimer's disease and insomnia: A systematic review and meta-analysis of randomized controlled trialsNeurosci Biobehav Rev.(2021 May 3)