Creatinine

    Last Updated: October 13, 2024

    Creatinine is a metabolic byproduct of creatine, and is sometimes used as a biomarker for kidney damage as it can accumulate when kidneys are impaired (despite creatine supplementation giving a false positive).

    5,699 participants in 46 trials

    Examine Database: Creatinine

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    Examine Database References

    1. Creatine - Deminice R, Rosa FT, Franco GS, Jordao AA, de Freitas ECEffects of creatine supplementation on oxidative stress and inflammatory markers after repeated-sprint exercise in humansNutrition.(2013 Sep)
    2. Saffron - Kianbakht S, Ghazavi AImmunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trialPhytother Res.(2011 Dec)
    3. Creatine - Kornblum C, Schröder R, Müller K, Vorgerd M, Eggers J, Bogdanow M, Papassotiropoulos A, Fabian K, Klockgether T, Zange JCreatine has no beneficial effect on skeletal muscle energy metabolism in patients with single mitochondrial DNA deletions: a placebo-controlled, double-blind 31P-MRS crossover studyEur J Neurol.(2005 Apr)
    4. Creatine - Mayhew DL, Mayhew JL, Ware JSEffects of long-term creatine supplementation on liver and kidney functions in American college football playersInt J Sport Nutr Exerc Metab.(2002 Dec)
    5. Roselle - Gurrola-Díaz CM, García-López PM, Sánchez-Enríquez S, Troyo-Sanromán R, Andrade-González I, Gómez-Leyva JFEffects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy)Phytomedicine.(2010 Jun)
    6. Saffron - Milajerdi A, et alThe effect of saffron (Crocus sativus L.) hydro-alcoholic extract on liver and renal functions in type 2 diabetic patients: A double-blinded randomized and placebo control trialJournal of Nutrition & Intermediary Metabolism.()
    7. Saffron - Fatemeh Ebrahimi, Naheed Aryaeian, Naseh Pahlavani, Davood Abbasi, Agha Fatemeh Hosseini, Soudabeh Fallah, Nariman Moradi, Iraj HeydariThe effect of saffron ( Crocus sativus L.) supplementation on blood pressure, and renal and liver function in patients with type 2 diabetes mellitus: A double-blinded, randomized clinical trialAvicenna J Phytomed.(Jul-Aug 2019)
    8. Theanine - Shinsuke Hidese, Miho Ota, Chisato Wakabayashi, Takamasa Noda, Hayato Ozawa, Tsutomu Okubo, Hiroshi KunugiEffects of chronic l-theanine administration in patients with major depressive disorder: an open-label studyActa Neuropsychiatr.(2017 Apr)
    9. Creatine - Volek JS, Mazzetti SA, Farquhar WB, Barnes BR, Gómez AL, Kraemer WJPhysiological responses to short-term exercise in the heat after creatine loadingMed Sci Sports Exerc.(2001 Jul)
    10. Saffron - Karimi-Nazari E, et alEffect of saffron (Crocus sativus L.) on lipid profile, glycemic indices and antioxidant status among overweight/obese prediabetic individuals: A double-blinded, randomized controlled trialClin Nutr ESPEN.()
    11. Rose Hip - Kharazmi A, Winther KRose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology.(1999)
    12. Ketogenic Diet - Boden G, Sargrad K, Homko C, Mozzoli M, Stein TPEffect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetesAnn Intern Med.(2005 Mar 15)
    13. Creatine - Manjarrez-Montes de Oca R, Farfán-González F, Camarillo-Romero S, Tlatempa-Sotelo P, Francisco-Argüelles C, Kormanowski A, González-Gallego J, Alvear-Ordenes IEffects of creatine supplementation in taekwondo practitionersNutr Hosp.(2013 Mar-Apr)
    14. Saffron - Modaghegh MH, Shahabian M, Esmaeili HA, Rajbai O, Hosseinzadeh HSafety evaluation of saffron (Crocus sativus) tablets in healthy volunteersPhytomedicine.(2008 Dec)
    15. Cissus Quadrangularis - Oben JE, Enyegue DM, Fomekong GI, Soukontoua YB, Agbor GAThe effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stressLipids Health Dis.(2007 Feb 4)
    16. Ketogenic Diet - Urbain P, Strom L, Morawski L, Wehrle A, Deibert P, Bertz HImpact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adultsNutr Metab (Lond).(2017 Feb 20)
    17. Glutamine - Galera SC, Fechine FV, Teixeira MJ, Coelho ZC, de Vasconcelos RC, de Vasconcelos PRThe safety of oral use of L-glutamine in middle-aged and elderly individualsNutrition.(2010 Apr)
    18. L-Carnitine - Aneliya Parvanova, Matias Trillini, Manuel A Podestà, Ilian P Iliev, Carolina Aparicio, Annalisa Perna, Francesco Peraro, Nadia Rubis, Flavio Gaspari, Antonio Cannata, Silvia Ferrari, Antonio C Bossi, Roberto Trevisan, Sreejith Parameswaran, Jonathan S Chávez-Iñiguez, Fahrudin Masnic, Sidy Mohamed Seck, Teerayuth Jiamjariyaporn, Monica Cortinovis, Luca Perico, Kanishka Sharma, Giuseppe Remuzzi, Piero Ruggenenti, David G WarnockBlood Pressure and Metabolic Effects of Acetyl-l-Carnitine in Type 2 Diabetes: DIABASI Randomized Controlled TrialJ Endocr Soc.(2018 Mar 22)
    19. L-Carnitine - M R Rubin, J S Volek, A L Gómez, N A Ratamess, D N French, M J Sharman, W J KraemerSafety measures of L-carnitine L-tartrate supplementation in healthy menJ Strength Cond Res.(2001 Nov)
    20. Ketogenic Diet - Athinarayanan SJ, Adams RN, Hallberg SJ, McKenzie AL, Bhanpuri NH, Campbell WW, Volek JS, Phinney SD, McCarter JPLong-Term Effects of a Novel Continuous Remote Care Intervention Including Nutritional Ketosis for the Management of Type 2 Diabetes: A 2-Year Non-randomized Clinical TrialFront Endocrinol (Lausanne).(2019 Jun 5)
    21. Saffron - Mansoori P, et alA Randomized, Double-blind, Placebo - controlled Study of Safety of the Adjunctive Saffron on Sexual Dysfunction Induced by a Selective Serotonin Reuptake InhibitorJ Med Plant .()
    22. Creatine - Earnest CP, Almada AL, Mitchell TLHigh-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and womenClin Sci (Lond).(1996 Jul)
    23. Creatine - Christiano R R Alves, Bianca M Santiago, Fernanda R Lima, Maria C G Otaduy, Ana Luisa Calich, Aline C C Tritto, Ana Lúcia de Sá Pinto, Hamilton Roschel, Cláudia C Leite, Fabiana B Benatti, Eloisa Bonfá, Bruno GualanoCreatine supplementation in fibromyalgia: a randomized, double-blind, placebo-controlled trialArthritis Care Res (Hoboken).(2013 Sep)
    24. Pterostilbene - Riche DM, McEwen CL, Riche KD, Sherman JJ, Wofford MR, Deschamp D, Griswold MAnalysis of safety from a human clinical trial with pterostilbeneJ Toxicol.(2013)
    25. Creatine - Tarnopolsky MA, Mahoney DJ, Vajsar J, Rodriguez C, Doherty TJ, Roy BD, Biggar DCreatine monohydrate enhances strength and body composition in Duchenne muscular dystrophyNeurology.(2004 May 25)
    26. Creatine - Tarnopolsky M, Mahoney D, Thompson T, Naylor H, Doherty TJCreatine monohydrate supplementation does not increase muscle strength, lean body mass, or muscle phosphocreatine in patients with myotonic dystrophy type 1Muscle Nerve.(2004 Jan)
    27. Saffron - Bentolhoda Mousavi, Seyedeh Zahra Bathaie, Farbod Fadai, Zabihollah Ashtari, Neda Ali Beigi, Sara Farhang, Sara Hashempour, Nasim Shahhamzei, Hamid HeidarzadehSafety evaluation of saffron stigma (Crocus sativus L.) aqueous extract and crocin in patients with schizophreniaAvicenna J Phytomed.(Sep-Oct 2015)
    28. Citrulline - Sureda A, Córdova A, Ferrer MD, Pérez G, Tur JA, Pons AL-citrulline-malate influence over branched chain amino acid utilization during exerciseEur J Appl Physiol.(2010 Sep)
    29. Creatine - Dabidi Roshan V, Babaei H, Hosseinzadeh M, Arendt-Nielsen LThe effect of creatine supplementation on muscle fatigue and physiological indices following intermittent swimming boutsJ Sports Med Phys Fitness.(2013 Jun)
    30. Creatine - Mendes RR, Pires I, Oliveira A, Tirapegui JEffects of creatine supplementation on the performance and body composition of competitive swimmersJ Nutr Biochem.(2004 Aug)
    31. Creatine - Schilling BK, Stone MH, Utter A, Kearney JT, Johnson M, Coglianese R, Smith L, O'Bryant HS, Fry AC, Starks M, Keith R, Stone MECreatine supplementation and health variables: a retrospective studyMed Sci Sports Exerc.(2001 Feb)
    32. Saffron - Armaghan Moravej Aleali, Reza Amani, Hajieh Shahbazian, Frough Namjooyan, Seyed Mahmoud Latifi, Bahman CheraghianThe effect of hydroalcoholic Saffron (Crocus sativus L.) extract on fasting plasma glucose, HbA1c, lipid profile, liver, and renal function tests in patients with type 2 diabetes mellitus: A randomized double-blind clinical trialPhytother Res.(2019 Jun)
    33. Vitamin C - JAYESH K BHATT, SABIN THOMAS, NANJAN MJEFFECT OF ORAL SUPPLEMENTATION OF VITAMIN C ON GLYCEMIC CONTROL AND LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES MELLITUSInternational Journal of Pharmacy and Pharmaceutical Sciences.()
    34. Vitamin E - Meydani SN, Barklund MP, Liu S, Meydani M, Miller RA, Cannon JG, Morrow FD, Rocklin R, Blumberg JBVitamin E supplementation enhances cell-mediated immunity in healthy elderly subjectsAm J Clin Nutr.(1990 Sep)
    35. Creatine - Shefner JM, Cudkowicz ME, Schoenfeld D, Conrad T, Taft J, Chilton M, Urbinelli L, Qureshi M, Zhang H, Pestronk A, Caress J, Donofrio P, Sorenson E, Bradley W, Lomen-Hoerth C, Pioro E, Rezania K, Ross M, Pascuzzi R, Heiman-Patterson T, Tandan R, Mitsumoto H, Rothstein J, Smith-Palmer T, MacDonald D, Burke D; NEALS ConsortiumA clinical trial of creatine in ALSNeurology.(2004 Nov 9)
    36. Spirulina - Gitte S Jensen, Cassandra Drapeau, Miki Lenninger, Kathleen F BensonClinical Safety of a High Dose of Phycocyanin-Enriched Aqueous Extract from Arthrospira (Spirulina) platensis: Results from a Randomized, Double-Blind, Placebo-Controlled Study with a Focus on Anticoagulant Activity and Platelet ActivationJ Med Food.(2016 Jul)
    37. Magnesium - Vázquez-Lorente H, Herrera-Quintana L, Molina-López J, Gamarra-Morales Y, López-González B, Miralles-Adell C, Planells EResponse of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain.Nutrients.(2020-Jul-30)
    38. Magnesium - Córdova A, Mielgo-Ayuso J, Roche E, Caballero-García A, Fernandez-Lázaro DImpact of Magnesium Supplementation in Muscle Damage of Professional Cyclists Competing in a Stage Race.Nutrients.(2019-Aug-16)
    39. Tongkat Ali - Chen CK, Mohamad WM, Ooi FK, Ismail SB, Abdullah MR, George ASupplementation of Eurycoma longifolia Jack Extract for 6 Weeks Does Not Affect Urinary Testosterone: Epitestosterone Ratio, Liver and Renal Functions in Male Recreational Athletes.Int J Prev Med.(2014-Jun)
    40. Resistant Starch - Du X, Wu J, Gao C, Tan Q, Xu YEffects of Resistant Starch on Patients with Chronic Kidney Disease: A Systematic Review and Meta-Analysis.J Diabetes Res.(2022)
    41. Resveratrol - Hausenblas HA, Schoulda JA, Smoliga JMResveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus--systematic review and meta-analysis.Mol Nutr Food Res.(2014 Aug 19)
    42. Resveratrol - Sahar Rafiee, Hamed Mohammadi, Abed Ghavami, Erfan Sadeghi, Zahra Safari, Gholamreza AskariEfficacy of resveratrol supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trialsComplement Ther Clin Pract.(2020 Dec 4)
    43. Resveratrol - Abdollahi S, Vajdi M, Meshkini F, Vasmehjani AA, Sangsefidi ZS, Clark CCT, Soltani SResveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.Nutr Res.(2023-May)
    44. Pycnogenol - Malekahmadi M, Moradi Moghaddam O, Firouzi S, Daryabeygi-Khotbehsara R, Shariful Islam SM, Norouzy A, Soltani SEffects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials.Pharmacol Res.(2019-Dec)
    45. Saffron - Amatto PPG, Chaves L, Braga GG, Carmona F, Pereira AMSEffect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.J Ethnopharmacol.(2023-Sep-29)
    46. Vitamin E - Meng L, Liu S, Cui WRenal protective effects of vitamin E for drug-induced kidney injury: a meta-analysis.Front Pharmacol.(2025)