Examine Database: Diarrhea Symptoms
| Intervention | Grade | Effect | Detail |
|---|---|---|---|
| Probiotics | A | ||
| Vitamin A | D | ||
| Colostrum | B | ||
| Zinc | |||
| Plantain | |||
| Lactase Enzyme | |||
| Kefir | |||
| Low-FODMAP Diet | |||
| Lactobacillus Reuteri | |||
| Psyllium | |||
| 16:8 Intermittent Fasting |
Research FeedRead all studies
Probiotics reduced diarrhea from chemotherapy
In this meta-analysis of 14 randomized controlled trials in participants who primarily had colorectal cancer, probiotics did not reduce the risk of diarrhea, compared to standard care, though this finding was of borderline statistical significance.
Supplemental zinc can improve diarrhea in children but may increase vomiting
Is a diet that restricts starch and sucrose as effective as a low-FODMAP diet for IBS?
Does taking a postbiotic improve diarrhea symptoms?
Can fermented gold kiwi improve GI symptoms?
Examine Database References
- Colostrum - P D Greenberg, J P CelloTreatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDSJ Acquir Immune Defic Syndr Hum Retrovirol.(1996 Dec 1)
- Colostrum - Kaducu FO, Okia SA, Upenytho G, Elfstrand L, Florén CHEffect of bovine colostrum-based food supplement in the treatment of HIV-associated diarrhea in Northern Uganda: a randomized controlled trialIndian J Gastroenterol.(2011 Dec)
- 16:8 Intermittent Fasting - Kelsey Gabel, Kristin K Hoddy, Krista A VaradySafety of 8-h time restricted feeding in adults with obesityAppl Physiol Nutr Metab.(2019 Jan)
- Zinc - Weismann K, Jakobsen JP, Weismann JE, Hammer UM, Nyholm SM, Hansen B, Lomholt KE, Schmidt KZinc gluconate lozenges for common cold. A double-blind clinical trialDan Med Bull.(1990 Jun)
- Low-FODMAP Diet - Dana M Lis, Trent Stellingwerff, Cecilia M Kitic, James W Fell, Kiran D K AhujaLow FODMAP: A Preliminary Strategy to Reduce Gastrointestinal Distress in AthletesMed Sci Sports Exerc.(2018 Jan)
- Lactobacillus Reuteri - Cimperman L, Bayless G, Best K, Diligente A, Mordarski B, Oster M, Smith M, Vatakis F, Wiese D, Steiber A, Katz JA randomized, double-blind, placebo-controlled pilot study of Lactobacillus reuteri ATCC 55730 for the prevention of antibiotic-associated diarrhea in hospitalized adultsJ Clin Gastroenterol.(2011 Oct)
- Colostrum - Otto W, Najnigier B, Stelmasiak T, Robins-Browne RMRandomized control trials using a tablet formulation of hyperimmune bovine colostrum to prevent diarrhea caused by enterotoxigenic Escherichia coli in volunteersScand J Gastroenterol.(2011 Jul)
- Colostrum - C O Tacket, G Losonsky, H Link, Y Hoang, P Guesry, H Hilpert, M M LevineProtection by milk immunoglobulin concentrate against oral challenge with enterotoxigenic Escherichia coliN Engl J Med.(1988 May 12)
- Lactase Enzyme - Cheng AH, Brunser O, Espinoza J, Fones HL, Monckeberg F, Chichester CO, Rand G, Hourigan AGLong-term acceptance of low-lactose milkAm J Clin Nutr.(1979 Oct)
- Kefir - Onder Bekar, Yusuf Yilmaz, Macit GultenKefir improves the efficacy and tolerability of triple therapy in eradicating Helicobacter pyloriJ Med Food.(2011 Apr)
- Colostrum - Florén CH, Chinenye S, Elfstrand L, Hagman C, Ihse IColoPlus, a new product based on bovine colostrum, alleviates HIV-associated diarrhoeaScand J Gastroenterol.(2006 Jun)
- Lactase Enzyme - Ojetti V, Gigante G, Gabrielli M, Ainora ME, Mannocci A, Lauritano EC, Gasbarrini G, Gasbarrini AThe effect of oral supplementation with Lactobacillus reuteri or tilactase in lactose intolerant patients: randomized trialEur Rev Med Pharmacol Sci.(2010 Mar)
- Colostrum - Tacket CO, Losonsky G, Livio S, Edelman R, Crabb J, Freedman DLack of prophylactic efficacy of an enteric-coated bovine hyperimmune milk product against enterotoxigenic Escherichia coli challenge administered during a standard mealJ Infect Dis.(1999 Dec)
- Colostrum - Rump JA, Arndt R, Arnold A, Bendick C, Dichtelmüller H, Franke M, Helm EB, Jäger H, Kampmann B, Kolb PTreatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrumClin Investig.(1992 Jul)
- Kefir - Daniel J Merenstein, Jennifer Foster, Frank D'AmicoA randomized clinical trial measuring the influence of kefir on antibiotic-associated diarrhea: the measuring the influence of Kefir (MILK) StudyArch Pediatr Adolesc Med.(2009 Aug)
- Lactase Enzyme - Rosado JL, Solomons NW, Lisker R, Bourges HEnzyme replacement therapy for primary adult lactase deficiency. Effective reduction of lactose malabsorption and milk intolerance by direct addition of beta-galactosidase to milk at mealtimeGastroenterology.(1984 Nov)
- Zinc - Lazzerini M, Wanzira HOral zinc for treating diarrhoea in children.Cochrane Database Syst Rev.(2016-Dec-20)
- Zinc - Lamberti LM, Walker CL, Chan KY, Jian WY, Black REOral zinc supplementation for the treatment of acute diarrhea in children: a systematic review and meta-analysis.Nutrients.(2013-Nov-21)
- Zinc - Galvao TF, Thees MF, Pontes RF, Silva MT, Pereira MGZinc supplementation for treating diarrhea in children: a systematic review and meta-analysis.Rev Panam Salud Publica.(2013-May)
- Vitamin A - Mayo-Wilson E, Imdad A, Herzer K, Yakoob MY, Bhutta ZAVitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis.BMJ.(2011-Aug-25)
- Psyllium - Kaewdech A, Sripongpun P, Wetwittayakhlang P, Churuangsuk CThe effect of fiber supplementation on the prevention of diarrhea in hospitalized patients receiving enteral nutrition: A meta-analysis of randomized controlled trials with the GRADE assessment.Front Nutr.(2022)
- Zinc - Ali AA, Naqvi SK, Hasnain Z, Zubairi MBA, Sharif A, Salam RA, Soofi S, Ariff S, Nisar YB, Das JKZinc supplementation for acute and persistent watery diarrhoea in children: A systematic review and meta-analysis.J Glob Health.(2024 Dec 6)
- Plantain - Gallo Ruelas M, Gomez-Herrera GP, Noa-Peralta KF, Regalado-Palacios G, Soria-Mamani M, Rojas-Armas JPRole of green banana consumption in the treatment of acute and persistent diarrhea in children: a systematic review and meta-analysis of randomized controlled trials.Eur J Pediatr.(2024 Sep)
- Probiotics - Siritientong T, Thet D, Leelakanok N, Areepium NOral probiotic supplementation to alleviate diarrhea induced by fluoropyrimidines or irinotecan-based chemotherapy: A systematic review and meta-analysis.Complement Ther Med.(2025 May)
- Probiotics - Li M, Xie YEfficacy and safety of Saccharomyces boulardii as an adjuvant therapy for the eradication of Helicobacter pylori: a meta-analysis.Front Cell Infect Microbiol.(2025)