Evidence-based

Endothelial Function

•Last Updated: October 13, 2024

Endothelial function (vasoreactivity) tends to refer to the reactivity of blood vessels to dilate or contract upon demand, and is associated with blood flow and arterial calcification. Improved vasoreactivity is associated with reduced risk for cardiovascular incidents.

Last Updated:October 13, 2024

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Coffee's chlorogenic acid may improve blood vessel function

In this meta-analysis of 19 randomized controlled trials in 443 participants, chlorogenic acid from coffee improved flow-mediated vasodilation (FMD, a marker of endothelial function), compared to various controls, with larger effects from regular consumption.