Ecdysteroids

    Written by:
    Megan Michaux

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    by:

    Nick Milazzo
    Last Updated: April 29, 2024

    Ecdysteroids are a type of steroid hormone found in arthropods, where they are responsible for reproduction and molting. Evidence for the use of ecdysteroids in humans is lacking, but they are often used to improve athletic performance and to stimulate muscle growth and are purported to have multiple other health benefits.

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    Overview

    Dosage information

    There is not enough research to recommend a specific dosage for each possible use of ecdysteroids, and most of the available research has been done on animals.

    Studies seem to show a dose-dependent response for hyperglycemia (high blood sugar). In in vivo liver cells from both diabetic and nondiabetic rats, higher doses of ecdysone resulted in a greater suppression of glucose production. However, research in humans is lacking, and there is not enough evidence to recommend a specific dose for people with diabetes.[1][2]

    For use in athletes, one study suggested 5 mg per kg of body weight as an effective dose but also noted that higher doses showed greater improvements in strength.[3] Another study found that 200 mg daily was ineffective for improving body composition.[4]

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    Examine Database References

    1. Testosterone - Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RBEffects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained malesJ Int Soc Sports Nutr.(2006 Dec 13)