Overview
What is umckaloabo?
What are umckaloabo’s main benefits?
What are umckaloabo’s main drawbacks?
How does umckaloabo work?
Dosage information
Formulation
Umckaloabo is most studied as an oral preparation (liquid drops, tablets, and syrups) of Pelargonium sidoides root extract. Liquid and tablet forms are typically cited in the current clinical evidence with dosage, frequency, and timing adjusted according to age and indication for use.[1][2][3][4][5][6][7][8][9]
EPs7630 is a commonly studied standardized extract, which contains an ethanol (11% w/w) extract at a ratio of 1:8–10.[2][7][8][9]
Range of dosages studied
Dosages vary across studies and populations and depend on age and formulation. For adults, total daily doses ranged from 90 mg to 7.2 grams, and children’s dosages tended to range from 30 mg to 3.6 grams per day. The most typical regimen for drops, regardless of age, was 10 to 30 drops per dose, three times per day (equating to about 120–240 mg per day). Tablets were more often dosed between 30 and 90 mg per day. Duration of treatment and follow-up after the study lasted anywhere from 5 to 21 days, with 7 to 10 days being the most frequent duration.[1][2][3][4][5][6][7][8][9]
Other Considerations
The most consistently used formulation in research is the standardized extract of EPs7630.[2][7][8][9]
Frequently asked questions
What are the known traditional, historical, and cultural uses of umckaloabo?
What are other names for Umckaloabo?
Research Breakdown
References
Examine Database References
- Bronchitis Symptoms - Agbabiaka TB, Guo R, Ernst EPelargonium sidoides for acute bronchitis: a systematic review and meta-analysisPhytomedicine.(2008 May)
 - Bronchitis Symptoms - Matthys H, Eisebitt R, Seith B, Heger MEfficacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. A randomised, double-blind, placebo-controlled trialPhytomedicine.(2003)
 - Bronchitis Symptoms - Matthys H, Kamin W, Funk P, Heger MPelargonium sidoides preparation (EPs 7630) in the treatment of acute bronchitis in adults and childrenPhytomedicine.(2007)
 - Bronchitis Symptoms - Chuchalin AG, Berman B, Lehmacher WTreatment of acute bronchitis in adults with a pelargonium sidoides preparation (EPs 7630): a randomized, double-blind, placebo-controlled trialExplore (NY).(2005 Nov)
 - Bronchitis Symptoms - Kamin W, Ilyenko LI, Malek FA, Kieser MTreatment of acute bronchitis with EPs 7630: randomized, controlled trial in children and adolescentsPediatr Int.(2012 Apr)
 - Bronchitis Symptoms - Matthys H, Funk PEPs 7630 improves acute bronchitic symptoms and shortens time to remission. Results of a randomised, double-blind, placebo-controlled, multicentre trialPlanta Med.(2008 May)
 - Bronchitis Symptoms - Matthys H, Heger MTreatment of acute bronchitis with a liquid herbal drug preparation from Pelargonium sidoides (EPs 7630): a randomised, double-blind, placebo-controlled, multicentre studyCurr Med Res Opin.(2007 Feb)
 - Bronchitis Symptoms - Matthys H, Lizogub VG, Malek FA, Kieser MEfficacy and tolerability of EPs 7630 tablets in patients with acute bronchitis: a randomised, double-blind, placebo-controlled dose-finding study with a herbal drug preparation from Pelargonium sidoidesCurr Med Res Opin.(2010 Jun)
 - Bronchitis Symptoms - Kamin W, Maydannik V, Malek FA, Kieser MEfficacy and tolerability of EPs 7630 in children and adolescents with acute bronchitis - a randomized, double-blind, placebo-controlled multicenter trial with a herbal drug preparation from Pelargonium sidoides rootsInt J Clin Pharmacol Ther.(2010 Mar)
 - Bronchitis Symptoms - Kamin W, Maydannik VG, Malek FA, Kieser MEfficacy and tolerability of EPs 7630 in patients (aged 6-18 years old) with acute bronchitisActa Paediatr.(2010 Apr)
 - Bronchitis Symptoms - Matthys H, Heger MEPs 7630-solution--an effective therapeutic option in acute and exacerbating bronchitisPhytomedicine.(2007)
 - Bronchitis Symptoms - Kardos P, Lehmacher W, Zimmermann A, Brandes-Schramm J, Funk P, Matthys H, Kamin WEffects of Pelargonium sidoides extract EPs 7630 on acute cough and quality of life - a meta-analysis of randomized, placebo-controlled trials.Multidiscip Respir Med.(2022 Jan 12)
 - Nasal Congestion - Bachert C, Schapowal A, Funk P, Kieser MTreatment of acute rhinosinusitis with the preparation from Pelargonium sidoides EPs 7630: a randomized, double-blind, placebo-controlled trialRhinology.(2009 Mar)
 - Asthma Symptoms - Tahan F, Yaman MCan the Pelargonium sidoides root extract EPs® 7630 prevent asthma attacks during viral infections of the upper respiratory tract in childrenPhytomedicine.(2013 Jan 15)
 - Cough - Wagner L, Cramer H, Klose P, Lauche R, Gass F, Dobos G, Langhorst JHerbal Medicine for Cough: a Systematic Review and Meta-Analysis.Forsch Komplementmed.(2015)
 - Lung Function - Matthys H, Pliskevich DA, Bondarchuk OM, Malek FA, Tribanek M, Kieser MRandomised, double-blind, placebo-controlled trial of EPs 7630 in adults with COPDRespir Med.(2013 May)
 - Fever - Lizogub VG, Riley DS, Heger MEfficacy of a pelargonium sidoides preparation in patients with the common cold: a randomized, double blind, placebo-controlled clinical trialExplore (NY).(2007 Nov-Dec)
 - Fever - Patiroglu T, Tunc A, Eke Gungor H, Unal EThe efficacy of Pelargonium sidoides in the treatment of upper respiratory tract infections in children with transient hypogammaglobulinemia of infancyPhytomedicine.(2012 Aug 15)
 - Common Cold Symptoms - Schapowal A, Dobos G, Cramer H, Ong KC, Adler M, Zimmermann A, Brandes-Schramm J, Lehmacher WTreatment of signs and symptoms of the common cold using EPs 7630 - results of a meta-analysis.Heliyon.(2019 Nov)
 - Immunoglobulin A - Luna LA Jr, Bachi AL, Novaes e Brito RR, Eid RG, Suguri VM, Oliveira PW, Gregorio LC, Vaisberg MImmune responses induced by Pelargonium sidoides extract in serum and nasal mucosa of athletes after exhaustive exercise: modulation of secretory IgA, IL-6 and IL-15Phytomedicine.(2011 Feb 15)
 - Upper Respiratory Tract Infection Symptoms - Anheyer D, Cramer H, Lauche R, Saha FJ, Dobos GHerbal Medicine in Children With Respiratory Tract Infection: Systematic Review and Meta-Analysis.Acad Pediatr.(2018 Jan-Feb)
 - Bronchitis Symptoms - Timmer A, Günther J, Motschall E, Rücker G, Antes G, Kern WVPelargonium sidoides extract for treating acute respiratory tract infections.Cochrane Database Syst Rev.(2013 Oct 22)
 





