Riboflavin (Vitamin B2)

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    Last Updated: February 18, 2026

    Riboflavin is an essential vitamin that’s necessary for energy metabolism, the antioxidant system, and the synthesis of many biological molecules. High-dose supplementation has been used for migraine prevention.

    Overview

    Dosage Information

    Formulation

    Most supplements contain riboflavin or riboflavin 5’-phosphate.

    Riboflavin is available as a single-ingredient oral tablet, capsule, or liquid, or in combination with other micronutrients (e.g., B-complex vitamins, multivitamins).

    Range of dosages studied

    Riboflavin has been studied at daily dosages ranging from 1.6 mg to 400 mg. The high dose of 400 mg has been used in the context of migraine headache prevention, with durations of up to 24 weeks.[1]

    Riboflavin recommended dietary allowance (RDA)

    The RDA for riboflavin is the amount that should be consumed daily to meet the nutritional needs of most people.

    AGEMALEFEMALEPREGNANTLACTATING
    0–6 months0.3 mg*0.3 mg*
    7–12 months0.4 mg*0.4 mg*
    1–3 years0.5 mg0.5 mg
    4–8 years0.6 mg0.6 mg
    9–13 years0.9 mg0.9 mg
    14–18 years1.3 mg1 mg1.4 mg1.6 mg
    19–50 years1.3 mg1.1 mg1.4 mg1.6 mg
    >50 years1.3 mg1.1 mg

    * Adequate intake (AI)
    Reference: Institute of Medicine. Riboflavin (chapter 5 of Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. The National Academies Press. 1998. DOI: 10.17226/6015)

    There is currently no established tolerable upper intake level for riboflavin.[2]

    Other considerations

    Riboflavin is sensitive to light, which can lead to its degradation.[3] Storing riboflavin in a dark container and avoiding exposure to light is recommended.

    Frequently Asked Questions

    Research Breakdown