Yohimbine

    Written by:

    Fact-checked

    by:

    Last Updated: October 13, 2024

    Yohimbine is promoted for its fat-burning properties and benefits for male sexual dysfunction. Though yohimbine is effective, side effects may include anxiety, nervousness, and an elevated heart rate, and the reported dose of yohimbine in many supplement formulas doesn’t match the actual dose.

    Overview

    Dosage information

    Total daily dosages of 0.2mg/kg bodyweight have been successfully used to increase fat burning without significant implications on cardiovascular parameters like heart rate and blood pressure. This results in a total daily dosage of:

    • 14 mg for a 150 lb (68 kg) person
    • 18 mg for a 200 lb (91 kg) person
    • 22 mg for a 250 lb (113 kg) person

    These total daily doses are often divided and taken in two to four doses throughout the day. For example, a 150 lb (68 kg) person could take 7 mg twice daily to reach to total dose of 14 mg.

    Supplementation is most effective between meals or during short term fasting.

    Caution should be exercised at higher body weight, since the cardiovascular system may not be prepared to handle a stimulatory agent such as yohimbine. When supplementing yohimbine for the first time, always start with a half-dose and assess tolerance before proceeding.

    Caution should also be exercised since many supplements containing yohimbine either do not list how much yohimbine is included, or if they do, the actual dose ranges from 25-150% of the dose listed. Since the dosage may be higher than listed, this is extra reason to start with a lower dose.

    When pairing yohimbine with other stimulatory agents, half-dose both supplements and work up to the recommended dose cautiously, as two supplements can interact negatively.

    Frequently asked questions

    Research Breakdown