The risk of many diseases increases significantly during aging, notably cardiovascular disease (CVD), various types of cancer, osteoporosis, osteoarthritis, cognitive decline and dementia, type 2 diabetes, sarcopenia (low muscle mass and function), infections, and age-related macular degeneration (AMD).[1][2][3][4] Some of these diseases can reduce both lifespan and healthspan, while some only (or primarily) reduce healthspan. Preventing or postponing these diseases can therefore support longevity and healthy aging.
References
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- ^Fleckenstein M, Keenan TDL, Guymer RH, Chakravarthy U, Schmitz-Valckenberg S, Klaver CC, Wong WT, Chew EYAge-related macular degeneration.Nat Rev Dis Primers.(2021-05-06)
- ^Loeser RFThe Role of Aging in the Development of Osteoarthritis.Trans Am Clin Climatol Assoc.(2017)
- ^Chandra A, Rajawat JSkeletal Aging and Osteoporosis: Mechanisms and Therapeutics.Int J Mol Sci.(2021-Mar-29)