Vitamin E

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    Last Updated: May 7, 2025

    Vitamin E is a fat-soluble antioxidant that protects cells from oxidative damage and is found in several common foods. Supplementing with extra vitamin E does not have broad health benefits, except in people with vitamin E deficiency, and long-term high-dose supplementation may cause harm.

    Overview

    Dosage information

    Formulation:

    Tablets typically containing alpha-tocopherol.

    Range of dosages studied:

    7 to 1,400 milligrams per day or 16.5 to 3111 international units (IU) per day.

    Effective Dosages:

    Inflammation

    Adults: The effective dosage for improving TNF-Alpha and CRP is 500–700 mg/day (1,111–1,555 IU/day), by mouth, for at least 8 weeks.[2]

    Special considerations: It is currently uncertain whether the effect of reducing TNF-Alpha and CRP leads to improved health outcomes.[2]

    Liver enzymes

    Adults: The effective dosage for improving AST and ALT (particularly in people with NAFLD) is 180–360 mg/day (400–800 IU/day), by mouth, for at least 1 month.[3][4]

    Special considerations: It is currently uncertain whether the effect of reducing liver enzymes in people with NAFLD leads to improved health outcomes.[4]

    Other Considerations:

    What is the recommended dietary allowance for vitamin E?

    The recommended dietary allowance (RDA) for vitamin E is as follows:[8]

    AgeRDA
    Male
    RDA
    Female
    RDA
    Pregnancy
    RDA
    Lactation
    0–6 months4 mg/day*4 mg/day*--
    6–12 months5 mg/day*5 mg/day*--
    1–3 years6 mg/day6 mg/day--
    4–8 years7 mg/day7 mg/day--
    9–13 years11 mg/day11 mg/day--
    14–18 years15 mg/day15 mg/day15 mg/day19 mg/day
    19+ years15 mg/day15 mg/day15 mg/day19 mg/day

    *Please note that the data for infants aged 0–12 months are adequate intake (AI) values, not RDA values.

    What is the tolerable upper intake level for vitamin E?

    The tolerable upper intake level (UL) for vitamin E is as follows:[8]

    AgeUL
    Male
    UL
    Female
    UL
    Pregnancy
    UL
    Lactation
    0–6 monthsnot definednot defined--
    6–12 monthsnot definednot defined--
    1–3 years200 mg/day200 mg/day--
    4–8 years300 mg/day300 mg/day--
    9–13 years600 mg/day600 mg/day--
    14–18 years800 mg/day800 mg/day800 mg/day800 mg/day
    19+ years1,000 mg/day1,000 mg/day1,000 mg/day1,000 mg/day

    Frequently asked questions

    Update History

    Research Breakdown