Total Antioxidant Capacity (TAC)

    Last Updated: October 13, 2024

    A measure of the antioxidant status of biological samples, often used to assess an organism’s antioxidant response to the free radicals caused by an illness or injury.

    20,941 participants in 58 trials

    Examine Database: Total Antioxidant Capacity (TAC)

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    Examine Database References

    1. Spirulina - Radhey Shyam, Som N Singh, Praveen Vats, Vijay K Singh, Rajeev Bajaj, Shashi B Singh, Pratul K BanerjeeWheat grass supplementation decreases oxidative stress in healthy subjects: a comparative study with spirulinaJ Altern Complement Med.(2007 Oct)
    2. Rhodiola Rosea - Jówko E, Sadowski J, Długołęcka B, Gierczuk D, Opaszowski B, Cieśliński IEffects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy menJ Sport Health Sci.(2018 Oct)
    3. Citrulline - S Azizi, M Ebrahimi-Mameghani, M Mobasseri, N Karamzad, R MahdaviOxidative stress and nitrate/nitrite (NOx) status following citrulline supplementation in type 2 diabetes: a randomised, double-blind, placebo-controlled trialJ Hum Nutr Diet.(2020 Jul 19)
    4. Curcumin - Campbell MS, Ouyang A, I M K, Charnigo RJ, Westgate PM, Fleenor BSInfluence of enhanced bioavailable curcumin on obesity-associated cardiovascular disease risk factors and arterial function: A double-blinded, randomized, controlled trialNutrition.(2019 Jun)
    5. Grape Juice - Park YK, Lee SH, Park E, Kim JS, Kang MHChanges in antioxidant status, blood pressure, and lymphocyte DNA damage from grape juice supplementationAnn N Y Acad Sci.(2009 Aug)
    6. L-Carnitine - Majid S Koozehchian, Amin Daneshfar, Ebrahim Fallah, Hamid Agha-Alinejad, Mohammad Samadi, Mojtaba Kaviani, Maryam Kaveh B, Y Peter Jung, Mozhgan Hassanzadeh Sablouei, Najmeh Moradi, Conrad P Earnest, T Jeff Chandler, Richard B KreiderEffects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained malesJ Exerc Nutrition Biochem.(2018 Dec 31)
    7. Saffron - Hajieh Shahbazian, Armaghan Moravej Aleali, Reza Amani, Foroogh Namjooyan, Bahman Cheraghian, Seyed Mahmoud Latifi, Sara Bahrainian, Ataallah GhadiriEffects of saffron on homocysteine, and antioxidant and inflammatory biomarkers levels in patients with type 2 diabetes mellitus: a randomized double-blind clinical trialAvicenna J Phytomed.(Sep-Oct 2019)
    8. Spirulina - Hee-Jung Park, Hyun-Sook LeeThe influence of obesity on the effects of spirulina supplementation in the human metabolic response of Korean elderlyNutr Res Pract.(2016 Aug)
    9. Coenzyme Q10 - Jahangard L, Yasrebifar F, Haghighi M, Ranjbar A, Mehrpooya MInfluence of adjuvant Coenzyme Q10 on inflammatory and oxidative stress biomarkers in patients with bipolar disorders during the depressive episodeMol Biol Rep.(2019 Oct)
    10. Curcumin - Adab Z, Eghtesadi S, Vafa MR, Heydari I, Shojaii A, Haqqani H, Arablou T, Eghtesadi MEffect of turmeric on glycemic status, lipid profile, hs-CRP, and total antioxidant capacity in hyperlipidemic type 2 diabetes mellitus patientsPhytother Res.(2019 Apr)
    11. Grape Juice - O'Byrne DJ, Devaraj S, Grundy SM, Jialal IComparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adultsAm J Clin Nutr.(2002 Dec)
    12. Astaxanthin - L. Wu, et alEffect of astaxanthin and exercise on antioxidant capacity of human body, blood lactic acid and blood uric acid metabolismSci Sports.()
    13. Curcumin - Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, Sripradha REfficacy of Turmeric as Adjuvant Therapy in Type 2 Diabetic PatientsIndian J Clin Biochem.(2015 Apr)
    14. Coenzyme Q10 - Mousavinejad E, Ghaffari MA, Riahi F, Hajmohammadi M, Tiznobeyk Z, Mousavinejad MCoenzyme Q10 supplementation reduces oxidative stress and decreases antioxidant enzyme activity in children with autism spectrum disordersPsychiatry Res.(2018 Jul)
    15. Vitamin D - Heidari H, Amani R, Feizi A, Askari G, Kohan S, Tavasoli PVitamin D Supplementation for Premenstrual Syndrome-Related inflammation and antioxidant markers in students with vitamin D deficient: a randomized clinical trialSci Rep.(2019 Oct 17)
    16. Saffron - Zahra Hamidi, Naheed Aryaeian, Jamileh Abolghasemi, Fatemeh Shirani, Mahsa Hadidi, Soudabeh Fallah, Nariman MoradiThe effect of saffron supplement on clinical outcomes and metabolic profiles in patients with active rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trialPhytother Res.(2020 Jul)
    17. Astaxanthin - Kim JH, Chang MJ, Choi HD, Youn YK, Kim JT, Oh JM, Shin WGProtective effects of Haematococcus astaxanthin on oxidative stress in healthy smokersJ Med Food.(2011 Nov)
    18. L-Carnitine - Aida Malek Mahdavi, Reza Mahdavi, Sousan Kolahi, Maryam Zemestani, Amir-Mansour VatankhahL-Carnitine supplementation improved clinical status without changing oxidative stress and lipid profile in women with knee osteoarthritisNutr Res.(2015 Aug)
    19. Astaxanthin - Chen JT, Kotani KEffects of Astaxanthin on Liver and Leukocyte Parameters in Healthy Climacteric Women: Preliminary DataJ Med Food.(2017 Jul)
    20. Grape Juice - Castilla P, Echarri R, Dávalos A, Cerrato F, Ortega H, Teruel JL, Lucas MF, Gómez-Coronado D, Ortuño J, Lasunción MAConcentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjectsAm J Clin Nutr.(2006 Jul)
    21. Theanine - A Juszkiewicz, A Glapa, P Basta, E Petriczko, K Żołnowski, B Machaliński, J Trzeciak, K Łuczkowska, A Skarpańska-StejnbornThe effect of L-theanine supplementation on the immune system of athletes exposed to strenuous physical exerciseJ Int Soc Sports Nutr.(2019 Feb 15)
    22. Coenzyme Q10 - Hadi Abdollahzad, Mir Amir Aghdashi, Mohammad Asghari Jafarabadi, Beitollah AlipourEffects of Coenzyme Q10 Supplementation on Inflammatory Cytokines (TNF-α, IL-6) and Oxidative Stress in Rheumatoid Arthritis Patients: A Randomized Controlled TrialArch Med Res.(2015 Oct)
    23. Vitamin D - Abolfazl Mehdizadehkashi, Samaneh Rokhgireh, Kobra Tahermanesh, Neda Eslahi, Sara Minaeian, Mansooreh SamimiThe effect of vitamin D supplementation on clinical symptoms and metabolic profiles in patients with endometriosisGynecol Endocrinol.(2021 Jan 29)
    24. Astaxanthin - Baralic I, Andjelkovic M, Djordjevic B, Dikic N, Radivojevic N, Suzin-Zivkovic V, Radojevic-Skodric S, Pejic SEffect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer PlayersEvid Based Complement Alternat Med.(2015)
    25. L-Carnitine - Seyed Mostafa Nachvak, Maryam Shabanpur, Roghayeh Mostafai, Reza Heidari Moghaddam, Jalal MoludiL-Carnitine supplementation reduces biomarkers of inflammatory and oxidative stress in patients with coronary artery disease: a randomised controlled trialArch Physiol Biochem.(2020 Aug 20)
    26. L-Carnitine - Hamidreza Jamilian, Mehri Jamilian, Mansooreh Samimi, Faraneh Afshar Ebrahimi, Maryam Rahimi, Fereshteh Bahmani, Sama Aghababayan, Mobina Kouhi, Sedighe Shahabbaspour, Zatollah AsemiOral carnitine supplementation influences mental health parameters and biomarkers of oxidative stress in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trialGynecol Endocrinol.(2017 Jun)
    27. Grape Juice - Hollis JH, Houchins JA, Blumberg JB, Mattes RDEffects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adultsJ Am Coll Nutr.(2009 Oct)
    28. Grape Juice - Toscano LT, Tavares RL, Toscano LT, Silva CS, Almeida AE, Biasoto AC, Gonçalves Mda C, Silva ASPotential ergogenic activity of grape juice in runnersAppl Physiol Nutr Metab.(2015 Sep)
    29. Saffron - Fatemeh Ebrahimi, Amirhossein Sahebkar, Naheed Aryaeian, Naseh Pahlavani, Soudabeh Fallah, Nariman Moradi, Davoud Abbasi, Agha Fatemeh HosseiniEffects Of Saffron Supplementation On Inflammation And Metabolic Responses In Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled TrialDiabetes Metab Syndr Obes.(2019 Oct 14)
    30. Kefir - GÖLÜNÜK, S et alEffects of traditional fermented beverages on some blood parameters in aerobic exercises.Biomedical Research.()
    31. Grape Juice - de Lima Tavares Toscano L, Silva AS, de França ACL, de Sousa BRV, de Almeida Filho EJB, da Silveira Costa M, Marques ATB, da Silva DF, de Farias Sena K, Cerqueira GS, da Conceição Rodrigues Gonçalves MA single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo studyEur J Nutr.(2019 Nov 15)
    32. Spirulina - Szulinska M, Gibas-Dorna M, Miller-Kasprzak E, Suliburska J, Miczke A, Walczak-Gałezewska M, Stelmach-Mardas M, Walkowiak J, Bogdanski PSpirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled studyEur Rev Med Pharmacol Sci.(2017 May)
    33. Fish Oil - T Pawełczyk, M Grancow-Grabka, E Trafalska, J Szemraj, A PawełczykOxidative stress reduction related to the efficacy of n-3 polyunsaturated fatty acids in first episode schizophrenia: Secondary outcome analysis of the OFFER randomized trialProstaglandins Leukot Essent Fatty Acids.(2017 Jun)
    34. Conjugated Linoleic Acid - Kim J, Paik HD, Shin MJ, Park EEight weeks of conjugated linoleic acid supplementation has no effect on antioxidant status in healthy overweight/obese Korean individualsEur J Nutr.(2012 Mar)
    35. L-Carnitine - Khadijeh Parandak, Hamid Arazi, Faegheh Khoshkhahesh, Babak Nakhostin-RoohiThe effect of two-week L-carnitine supplementation on exercise -induced oxidative stress and muscle damageAsian J Sports Med.(2014 Jun)
    36. Magnesium - Nicola Veronese, Damiano Pizzol, Lee Smith, Ligia J Dominguez, Mario BarbagalloEffect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled TrialsNutrients.(2022 Feb 5)
    37. Magnesium - Reihaneh Mousavi, Mohammad Alizadeh, Mohammad Asghari Jafarabadi, Lida Heidari, Roshan Nikbakht, Hossein Babaahmadi Rezaei, Majid KarandishEffects of Melatonin and/or Magnesium Supplementation on Biomarkers of Inflammation and Oxidative Stress in Women with Polycystic Ovary Syndrome: a Randomized, Double-Blind, Placebo-Controlled TrialBiol Trace Elem Res.(2021 May 19)
    38. Magnesium - Chua FB, Cinco JE, Paz-Pacheco EEfficacy of Magnesium Supplementation on Glycemic Control in Type 2 Diabetes Patients: A Meta-analysis.J ASEAN Fed Endocr Soc.(2017)
    39. Magnesium - Qu Q, Rong R, Yu JEffect of magnesium supplementation on pregnancy outcome in gestational diabetes mellitus patients: A meta-analysis of randomized controlled trials.Food Sci Nutr.(2022-Oct)
    40. Rhodiola Rosea - Yu H, Lei T, Su X, Zhang L, Feng Z, Dong M, Hou Z, Guo H, Liu JEfficacy and safety of three species of L. in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis.Front Pharmacol.(2023)
    41. Chromium - Morvaridzadeh M, Estêvão MD, Qorbani M, Heydari H, Hosseini AS, Fazelian S, Belančić A, Persad E, Rezamand G, Heshmati JThe effect of chromium intake on oxidative stress parameters: A systematic review and meta-analysis.J Trace Elem Med Biol.(2022-Jan)
    42. Hesperidin - Buzdağlı Y, Eyipınar CD, Kacı FN, Tekin AEffects of hesperidin on anti-inflammatory and antioxidant response in healthy people: a meta-analysis and meta-regression.Int J Environ Health Res.(2022-Jun-28)
    43. Resistant Starch - Wei Y, Zhang X, Meng Y, Wang Q, Xu H, Chen LThe Effects of Resistant Starch on Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis.Nutr Cancer.(2022)
    44. Folic Acid (Vitamin B9) - Asbaghi O, Ghanavati M, Ashtary-Larky D, Bagheri R, Rezaei Kelishadi M, Nazarian B, Nordvall M, Wong A, Dutheil F, Suzuki K, Alavi Naeini AEffects of Folic Acid Supplementation on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Antioxidants (Basel).(2021-May-28)
    45. Coenzyme Q10 - Dai S, Tian Z, Zhao D, Liang Y, Liu M, Liu Z, Hou S, Yang YEffects of Coenzyme Q10 Supplementation on Biomarkers of Oxidative Stress in Adults: A GRADE-Assessed Systematic Review and Updated Meta-Analysis of Randomized Controlled Trials.Antioxidants (Basel).(2022-Jul-13)
    46. Spirulina - Fatemeh Naeini, Meysam Zarezadeh, Sara Mohiti, Helda Tutunchi, Mehrangiz Ebrahimi Mamaghani, Alireza OstadrahimiSpirulina supplementation as an adjuvant therapy in enhancement of antioxidant capacity: A systematic review and meta-analysis of controlled clinical trialsInt J Clin Pract.(2021 Jul 8)
    47. Resveratrol - Omidian M, Abdolahi M, Daneshzad E, Sedighiyan M, Aghasi M, Abdollahi H, Omidian P, Dabiri S, Mahmoudi MThe Effects of Resveratrol on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Endocr Metab Immune Disord Drug Targets.(2020)
    48. Resveratrol - Koushki M, Lakzaei M, Khodabandehloo H, Hosseini H, Meshkani R, Panahi GTherapeutic effect of resveratrol supplementation on oxidative stress: a systematic review and meta-analysis of randomised controlled trials.Postgrad Med J.(2020-Apr)
    49. Black seed - Kavyani Z, Musazadeh V, Golpour-Hamedani S, Moridpour AH, Vajdi M, Askari GThe effect of Nigella sativa (black seed) on biomarkers of inflammation and oxidative stress: an updated systematic review and meta-analysis of randomized controlled trials.Inflammopharmacology.(2023-Jun)
    50. Saffron - Abedi A, Ghobadi H, Sharghi A, Iranpour S, Fazlzadeh M, Aslani MREffect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials.Front Med (Lausanne).(2023)
    51. Molecular Hydrogen - Li Y, Bing R, Liu M, Shang Z, Huang Y, Zhou K, Bao D, Zhou JCan molecular hydrogen supplementation reduce exercise-induced oxidative stress in healthy adults? A systematic review and meta-analysis.Front Nutr.(2024)
    52. Dietary Approaches to Stop Hypertension (DASH) Diet - Pirouzeh R, Heidarzadeh-Esfahani N, Morvaridzadeh M, Izadi A, Yosaee S, Potter E, Heshmati J, Pizarro AB, Omidi A, Heshmati SEffect of DASH diet on oxidative stress parameters: A systematic review and meta-analysis of randomized clinical trials.Diabetes Metab Syndr.(2020 Nov-Dec)
    53. Probiotics - Farajipour H, Matin HR, Asemi Z, Sadr S, Tajabadi-Ebrahimi M, Sharifi N, Banikazemi Z, Taghizadeh M, Mirzaei HThe effects of probiotics supplements on metabolic indices and clinical signs in patients with diabetic retinopathy, a randomized double blind clinical trial.J Diabetes Metab Disord.(2024 Jun)
    54. Flaxseed - Musazadeh V, Jafarzadeh J, Keramati M, Zarezadeh M, Ahmadi M, Farrokhian Z, Ostadrahimi AFlaxseed Oil Supplementation Augments Antioxidant Capacity and Alleviates Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evid Based Complement Alternat Med.(2021)
    55. Flaxseed - Tamtaji OR, Milajerdi A, Reiner Ž, Dadgostar E, Amirani E, Asemi Z, Mirsafaei L, Mansournia MA, Dana PM, Sadoughi F, Hallajzadeh JEffects of flaxseed oil supplementation on biomarkers of inflammation and oxidative stress in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials.Clin Nutr ESPEN.(2020 Dec)
    56. Omega-3 Fatty Acids - Muzammil K, Khaleel AQ, Merza MS, Kyada A, Ariffin IA, Verma S, Kaur H, Hasaanzadeh SThe effects of ω-3 fatty acids on inflammatory and oxidative stress markers in patients with Type 2 diabetes mellitus: A systematic review and meta-analysis of controlled trials.Prostaglandins Other Lipid Mediat.(2024 Sep 5)
    57. Cinnamon - Impact of Cinnamon Supplementation on cardiometabolic Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.()
    58. Cinnamon - Sarmadi B, Musazadeh V, Dehghan P, Karimi EThe effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis.(2023 Oct)