Cinnamon

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    Last Updated: November 20, 2024

    Cinnamon is a spice derived from the bark of trees in the Cinnamomum genus. Molecules found in cinnamon have antioxidant, antimicrobial, and anti-inflammatory properties. Supplementation with cinnamon might improve blood glucose, blood lipids, blood pressure, and some biomarkers of inflammation. However, cinnamon can have adverse effects when taken in large amounts.

    Overview

    Dosage information

    Formulations:

    Powder, stick, and tablets.

    Range of dosages studied:

    0.1 to 14 grams per day (g/day).

    Effective Dosages:

    Glycemic control (including blood glucose and HbA1c)

    Adults: Due to a lack of dose-response studies and variable findings from meta-regression studies, the precise effective dosage for improving glycemic control is uncertain, but it might be approximately 2 to 4 grams/day.[1][2][3][4][5]

    Special considerations: It is unclear whether cinnamon should be taken with food or not, because the efficacy of cinnamon on glycemic control has not been thoroughly examined in the presence vs. the absence of food.

    Blood lipids (including triglycerides, LDL, and total cholesterol)

    Adults: Due to a lack of dose-response studies and variable findings from meta-regression studies, the precise effective dosage for improving blood pressure is uncertain, but it might be approximately 1 to 6 grams/day.[6][7][8][9][10][11]

    Special considerations: It is unclear whether cinnamon should be taken with food or not, because the efficacy of cinnamon on blood lipids has not been thoroughly examined in the presence vs. the absence of food.

    Blood pressure

    Adults: Due to a lack of dose-response studies and variable findings from meta-regression studies, the precise effective dosage for improving blood pressure is uncertain, but it might be less than or equal to 2 grams/day.[12][13][14]

    Special considerations: It is unclear whether cinnamon should be taken with food or not, because the efficacy of cinnamon on blood pressure has not been thoroughly examined in the presence vs. the absence of food.

    Inflammation and oxidative stress

    Adults: Due to a lack of dose-response studies and variable findings from meta-regression studies, the precise effective dosage for improving blood pressure is uncertain, but it might be approximately 1 to 3 grams/day.[15][16][6]

    Special considerations: It is unclear whether cinnamon should be taken with food or not, because the efficacy of cinnamon on blood pressure has not been thoroughly examined in the presence vs. the absence of food.

    Other Considerations:

    Because of its coumarin content, cinnamon has the potential to interact negatively with blood-thinning medications and hepatotoxic drugs. See What are cinnamon’s main drawbacks? for further details.

    Examine Database: Cinnamon

    Research FeedRead all studies

    Frequently asked questions

    Update History

    Research Breakdown

    Examine Database References

    1. Blood glucose - de Moura SL, Gomes BGR, Guilarducci MJ, Coelho OGL, Guimarães NS, Gomes JMGEffects of cinnamon supplementation on metabolic biomarkers in individuals with type 2 diabetes: a systematic review and meta-analysis.Nutr Rev.(2024 Jun 25)
    2. Blood glucose - Zhou Q, Lei X, Fu S, Li Z, Chen Y, Long C, Li S, Chen QEfficacy of cinnamon supplementation on glycolipid metabolism in T2DM diabetes: A meta-analysis and systematic review.Front Physiol.(2022)
    3. Blood glucose - Leach MJ, Kumar SCinnamon for diabetes mellitus.Cochrane Database Syst Rev.(2012 Sep 12)
    4. Blood glucose - Moridpour AH, Kavyani Z, Khosravi S, Farmani E, Daneshvar M, Musazadeh V, Faghfouri AHThe effect of cinnamon supplementation on glycemic control in patients with type 2 diabetes mellitus: An updated systematic review and dose-response meta-analysis of randomized controlled trials.Phytother Res.(2024-Jan)
    5. Total cholesterol - Jamali N, Kazemi A, Saffari-Chaleshtori J, Samare-Najaf M, Mohammadi V, Clark CCTThe effect of cinnamon supplementation on lipid profiles in patients with type 2 diabetes: A systematic review and meta-analysis of clinical trials.Complement Ther Med.(2020 Dec)
    6. Total cholesterol - Maierean SM, Serban MC, Sahebkar A, Ursoniu S, Serban A, Penson P, Banach M, Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) GroupThe effects of cinnamon supplementation on blood lipid concentrations: A systematic review and meta-analysis.J Clin Lipidol.(2017 Nov-Dec)
    7. Total cholesterol - Fateh HL, Amin SMEffects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Clin Nutr Res.(2024-Jan)
    8. Low-density lipoprotein (LDL) - Krittanawong C, Isath A, Scott CZ, Wang Z, Kaplin S, Jneid H, Lavie CJ, Virani SSAssociation Between Cinnamon Consumption and Risk of Cardiovascular Health: A Systematic Review and Meta-Analysis.Am J Med.(2022 Jan)
    9. Low-density lipoprotein (LDL) - Sarmadi B, Musazadeh V, Dehghan P, Karimi EThe effect of cinnamon consumption on lipid profile, oxidative stress, and inflammation biomarkers in adults: An umbrella meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis.(2023 Oct)
    10. C-Reactive Protein (CRP) - Natalia Vallianou, Catherine Tsang, Mohsen Taghizadeh, Amirhossein Davoodvandi, Sadegh JafarnejadEffect of cinnamon (Cinnamomum Zeylanicum) supplementation on serum C-reactive protein concentrations: A meta-analysis and systematic reviewComplement Ther Med.(2019 Feb)
    11. C-Reactive Protein (CRP) - Zhu C, Yan H, Zheng Y, Santos HO, Macit MS, Zhao KImpact of Cinnamon Supplementation on cardiometabolic Biomarkers of Inflammation and Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Complement Ther Med.(2020 Sep)
    12. Blood Pressure - Mousavi SM, Karimi E, Hajishafiee M, Milajerdi A, Amini MR, Esmaillzadeh AAnti-hypertensive effects of cinnamon supplementation in adults: A systematic review and dose-response Meta-analysis of randomized controlled trials.Crit Rev Food Sci Nutr.(2020)
    13. Blood Pressure - Ghavami A, Haghighian HK, Roshanravan N, Ziaei R, Ghaedi E, Moravejolahkami AR, Askari GWhat is the Impact of Cinnamon Supplementation on Blood Pressure? A Systematic Review and Meta-Analysis.Endocr Metab Immune Disord Drug Targets.(2021)
    14. Blood Pressure - Hadi A, Campbell MS, Hassani B, Pourmasoumi M, Salehi-Sahlabadi A, Hosseini SAThe effect of cinnamon supplementation on blood pressure in adults: A systematic review and meta-analysis of randomized controlled trials.Clin Nutr ESPEN.(2020 Apr)
    15. Insulin Resistance - Heshmati J, Sepidarkish M, Morvaridzadeh M, Farsi F, Tripathi N, Razavi M, Rezaeinejad MThe effect of cinnamon supplementation on glycemic control in women with polycystic ovary syndrome: A systematic review and meta-analysis.J Food Biochem.(2021 Jan)