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Apolipoprotein B

Apolipoprotein B is the primary apolipoprotein (protein part of a lipoprotein) for LDL cholesterol, and increasing expression of apolipoprotein B is thought to help increase uptake of LDL from the blood into tissues.

Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect apolipoprotein b
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b Fish Oil - Moderate See all 6 studies
Although at least one study has noted a decrease, usually there is no significant changes
grade-c Hesperidin Minor Very High See all 3 studies
There appear to be mild decreases of circulating Apolipoprotein B seen with supplementation of hesperidin in the populations with poor baseline cholesterol that actually see benefit from supplementation.
grade-c Pueraria mirifica Minor - See study
A slight decrease in Apolipoprotein B has been noted with Pueraria Mirifica
grade-c Zinc  
grade-c Astaxanthin  
grade-c Chromium  
grade-c Garcinia cambogia  
grade-c Ginkgo biloba  
grade-c Lactobacillus reuteri  
grade-c Vitamin B3 (Niacin)  
grade-d Red Clover Extract  
grade-d Yerba mate  
grade-d Hibiscus sabdariffa  
grade-d Krill Oil  
grade-d Medium-chain triglycerides  
grade-d Pueraria lobata  
grade-d Tetradecyl Thioacetic Acid  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.