Peripheral Arterial Disease falls under the Cardiovascular Health category.

Evidence-based

Peripheral Arterial Disease

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Fact-checked by:

Morgan Pfiffner, Shyam Jayaraman

•Last Updated: November 20, 2025

Peripheral arterial disease is a condition characterized by a narrowing of the arteries that carry blood away from the heart to other parts of the body. It is usually caused by atherosclerosis. The legs and feet are most commonly affected, resulting in reduced blood flow to these areas.

Written by:

Fact-checked by:

Last Updated:November 20, 2025

Research Snapshot

39 references on this page

2,629 participants in 16 trials and 2 meta-analyses

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Overview

What is peripheral arterial disease?

What are the main signs and symptoms of peripheral arterial disease?

How is peripheral arterial disease diagnosed?

What are some of the main medical treatments for peripheral arterial disease?

Have any supplements been studied for peripheral arterial disease?

How could diet affect peripheral arterial disease?

Are there any other treatments for peripheral arterial disease?

What causes peripheral arterial disease?

Examine Database: Peripheral Arterial Disease

11 outcomes

4 outcomes

9 outcomes

4 outcomes

5 outcomes

Alpha-Lipoic Acid

2 outcomes

1 outcome

1 outcome

3 outcomes

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Frequently Asked Questions

What are the risk factors for peripheral arterial disease?

References

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