L-Tyrosine

    Last Updated: September 4, 2025

    L-Tyrosine is an amino acid that is used as a precursor for the synthesis of the catecholamines dopamine (DA) and norepinephrine (NE). DA and NE are depleted under stressful conditions, which can compromise cognitive function. L-Tyrosine supplementation may help alleviate acute stress-induced cognitive decline by restoring catecholamine levels in the brain.

    Overview

    Dosage Information

    Anecdotally, L-Tyrosine tends to be taken in doses of 500–2000 mg approximately 30–60 minutes before any acute stressor (this tends to be exercise).

    Studies in humans showing most anti-stress promise for acute supplemental L-Tyrosine use a dosage range of 100–150 mg/kg of bodyweight which can be taken 60 minutes before exercise; this is a dosage range of 9–13.5 g for a 200 lb person and 7–10 g for a 150 lb person.

    If using higher doses and finding digestive issues, this may be split into two doses separated by half an hour (30 and 60 minutes prior to acute stress).

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    Research Breakdown