Oxidation of LDL
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect oxidation of ldl
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Notable
|
Very High See all 8 studies |
The decrease in LDL oxidation seen with olive oil phenolics appears to be of notable potency due to its reliability (occurring in both healthy persons and diseased persons, chronically and acutely) and a reduction in LDL oxidation rates can exceed 25% in some studies with low intakes of olive phenolics (enough from virgin olive oil consumption)
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- | High See all 5 studies |
The majority of evidence does not find a significant alteration in the rate of LDL oxidation with cocoa or its isolated flavanols relative to placebo.
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Notable
|
Moderate See 2 studies |
In high risk individuals, the reduction has been noted to be 17.0+/-5.5%
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