Oxygen Uptake

    Researchedby:
    Brady Holmer

    Fact-checked

    by:

    Nick Milazzo, Molly Gregas
    Last Updated: October 13, 2024

    Oxygen uptake is the amount of oxygen used by the body at rest or during exercise and is directly related to the body’s energy expenditure.

    examine-databaseExamine Database
    1 reference on this page
    4,547 participants in 94 trials

    Summary

    Oxygen uptake is commonly referred to as VO2, which stands for the volume (V) of oxygen (O2) being consumed by the body. VO2 is measured in liters of oxygen per minute (L/min) and therefore represents the rate at which oxygen is being consumed by metabolically active tissues (e.g., muscle).

    Oxygen uptake can be used to calculate total body energy expenditure using a method known as indirect calorimetry. Though VO2 can be measured at rest, it’s more commonly measured during exercise.

    When oxygen uptake is measured during an exercise test performed to exhaustion, we can determine someone’s VO2max — the maximal rate at which the body can consume oxygen during exercise.

    VO2max is seen as the single best indicator of cardiorespiratory or aerobic fitness because as you become fitter, your body becomes better at using oxygen to produce energy and your VO2max increases. However, a higher VO2max doesn’t always translate to improved exercise or sports performance because some activities involve moments when energy requirements are so great (the intensity is so high) that oxygen isn’t used to generate the required energy. This is known as anaerobic (“without oxygen”) exercise.

    Elite endurance athletes often have a very high VO2max, but this is just one aspect that determines aerobic exercise performance. Furthermore, oxygen uptake is also recognized as an important factor in healthspan and longevity, and having a higher VO2 max is associated with reduced all-cause mortality.[1]

    Examine Database: Oxygen Uptake

    Ketogenic Diet
    D
    No effect
    Sodium Bicarbonate
    D
    No effect
    Creatine
    B
    Small Improvement
    Panax Ginseng (Korean Ginseng)
    L-Carnitine
    Colostrum
    Beta-Alanine
    Ashwagandha
    Nitrate
    Fish Oil
    Coenzyme Q10
    Sauna
    Tart Cherry Juice
    Eleuthero
    L-Tyrosine
    Vitamin D
    Caffeine
    Spirulina
    Cordyceps
    Rhodiola Rosea
    Curcumin
    Ginkgo Biloba
    Saffron
    Echinacea
    Kefir
    Whey Protein
    Branched-Chain Amino Acids
    HMB
    Vitamin C
    Green Tea Extract
    Capsaicin
    Resveratrol
    Astaxanthin
    Iron
    Cannabis
    Conjugated Linoleic Acid
    Garlic
    Yerba Mate
    Ornithine
    Citrulline
    Betaine

    Research FeedRead all studies

    References

    1. ^Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber WAssociation of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing.JAMA Netw Open.(2018-10-05)

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    39. Green Tea Extract - Richards JC, Lonac MC, Johnson TK, Schweder MM, Bell CEpigallocatechin-3-gallate increases maximal oxygen uptake in adult humansMed Sci Sports Exerc.(2010 Apr)
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