Pain

    Last Updated: October 13, 2024

    Pain is the adverse sensation associated with injury, arthritis, and various forms of nerve injury that impairs well being and day-to-day living. Supplements may either universally reduce pain, or may alleviate the pain associated with a disease state.

    examine-databaseExamine Database
    14,061 participants in 87 trials

    Examine Database: Pain

    Curcumin
    A
    Moderate Improvement
    Cannabis
    B
    Small Improvement
    Glucosamine
    B
    Small Improvement
    Type-II Collagen
    Serrapeptase
    Rose Hip
    Aloe Vera
    Cannabidiol (CBD)
    Binaural Beats
    Ashwagandha
    Magnesium
    Coenzyme Q10
    S-adenosylmethionine
    L-Carnitine
    Progressive Muscle Relaxation
    Tart Cherry Juice
    Rhodiola Rosea
    Horse Chestnut
    Cissus Quadrangularis
    Black seed
    Saffron
    Peppermint
    Rose Essential Oil
    Agmatine
    Vitamin D
    Pycnogenol
    Resveratrol
    Boron
    ECA
    Microlactin
    Valerian
    PQQ
    MSM
    Creatine
    Aerobic Exercise
    Massage
    Yoga

    Research FeedRead all studies

    Examine Database References

    1. Curcumin - Srivastava S, Saksena AK, Khattri S, Kumar S, Dagur RSCurcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled trialInflammopharmacology.(2016 Dec)
    2. Binaural Beats - Vasileios Gkolias, Aikaterini Amaniti, Areti Triantafyllou, Panagiota Papakonstantinou, Panagiotis Kartsidis, Evangelos Paraskevopoulos, Panagiotis D Bamidis, Leontios Hadjileontiadis, Dimitrios KouvelasReduced pain and analgesic use after acoustic binaural beats therapy in chronic pain - A double-blind randomized control cross-over trialEur J Pain.(2020 Jun 21)
    3. Serrapeptase - Kee WH, Tan SL, Lee V, Salmon YMThe treatment of breast engorgement with Serrapeptase (Danzen): a randomised double-blind controlled trialSingapore Med J.(1989 Feb)
    4. Type-II Collagen - Crowley DC, Lau FC, Sharma P, Evans M, Guthrie N, Bagchi M, Bagchi D, Dey DK, Raychaudhuri SPSafety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trialInt J Med Sci.(2009 Oct 9)
    5. Cannabis - Ziva D Cooper, Sandra D Comer, Margaret HaneyComparison of the analgesic effects of dronabinol and smoked marijuana in daily marijuana smokersNeuropsychopharmacology.(2013 Sep)
    6. Glucosamine - Pavelká K, Gatterová J, Olejarová M, Machacek S, Giacovelli G, Rovati LCGlucosamine sulfate use and delay of progression of knee osteoarthritis: a 3-year, randomized, placebo-controlled, double-blind studyArch Intern Med.(2002 Oct 14)
    7. Vitamin D - McAlindon T, LaValley M, Schneider E, Nuite M, Lee JY, Price LL, Lo G, Dawson-Hughes BEffect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trialJAMA.(2013 Jan 9)
    8. Curcumin - Haroyan A, Mukuchyan V, Mkrtchyan N, Minasyan N, Gasparyan S, Sargsyan A, Narimanyan M, Hovhannisyan AEfficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled studyBMC Complement Altern Med.(2018 Jan 9)
    9. Cannabis - Jeremy R Johnson, Dominique Lossignol, Mary Burnell-Nugent, Marie T FallonAn open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesicsJ Pain Symptom Manage.(2013 Aug)
    10. Black seed - Gheita TA, Kenawy SAEffectiveness of Nigella sativa oil in the management of rheumatoid arthritis patients: a placebo controlled studyPhytother Res.(2012 Aug)
    11. Rose Hip - Rein E, Kharazmi A, Winther KA herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis--a double-blind, placebo-controlled, randomised trialPhytomedicine.(2004 Jul)
    12. ECA - Schachtel BP, Voelker M, Sanner KM, Gagney D, Bey M, Schachtel EJ, Becka MDemonstration of the analgesic efficacy and dose-response of acetylsalicylic acid with pseudoephedrineJ Clin Pharmacol.(2010 Dec)
    13. Pycnogenol - Reza Farid, Zahra Mirfeizi, Mahyar Mirheidari, Zahra Rezaieyazdi, Hassan Mansouri, Habib Esmaelli, Sherma Zibadi, Peter Rohdewald, Ronald Ross WatsonPycnogenol supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritisNutrition Research.()
    14. Serrapeptase - Murugesan K, Sreekumar K, Sabapathy BComparison of the roles of serratiopeptidase and dexamethasone in the control of inflammation and trismus following impacted third molar surgeryIndian J Dent Res.(2012 Nov-Dec)
    15. Glucosamine - Clegg DO, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, Bradley JD, Bingham CO 3rd, Weisman MH, Jackson CG, Lane NE, Cush JJ, Moreland LW, Schumacher HR Jr, Oddis CV, Wolfe F, Molitor JA, Yocum DE, Schnitzer TJ, Furst DE, Sawitzke AD, Shi H, Brandt KD, Moskowitz RW, Williams HJGlucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritisN Engl J Med.(2006 Feb 23)
    16. Serrapeptase - Chopra D, Rehan HS, Mehra P, Kakkar AKA randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain modelInt J Oral Maxillofac Surg.(2009 Apr)
    17. Type-II Collagen - P. Benito-RuizM.M. Camacho-Zambrano, J.N. Carrillo-Arcentales, M.A. Mestanza-Peralta, C.A. Vallejo-Flores, S.V. Vargas-López, R.A. Villacís-Tamayo and L.A. Zurita-GavilanesA randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfortInternational Journal of Food Sciences and Nutrition.()
    18. Agmatine - Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GMSafety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled TrialPain Med.(2010 Mar)
    19. Curcumin - Di Pierro F, Rapacioli G, Di Maio EA, Appendino G, Franceschi F, Togni SComparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva(®)), nimesulide, and acetaminophenJ Pain Res.(2013)
    20. Glucosamine - Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, Reichenbach S, Trelle SEffects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysisBMJ.(2010 Sep 16)
    21. Cannabis - Jeremy R Johnson, Mary Burnell-Nugent, Dominique Lossignol, Elena Doina Ganae-Motan, Richard Potts, Marie T FallonMulticenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related painJ Pain Symptom Manage.(2010 Feb)
    22. Curcumin - Nakagawa Y, Mukai S, Yamada S, Matsuoka M, Tarumi E, Hashimoto T, Tamura C, Imaizumi A, Nishihira J, Nakamura TShort-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective studyJ Orthop Sci.(2014 Nov)
    23. Rose Essential Oil - Ayan M, Tas U, Sogut E, Suren M, Gurbuzler L, Koyuncu FInvestigating the Effect of Aromatherapy in Patients With Renal ColicJ Altern Complement Med.(2012 Oct 16)
    24. Cannabis - Dinesh Selvarajah, Rajiv Gandhi, Celia J Emery, Solomon TesfayeRandomized placebo-controlled double-blind clinical trial of cannabis-based medicinal product (Sativex) in painful diabetic neuropathy: depression is a major confounding factorDiabetes Care.(2010 Jan)
    25. Serrapeptase - Mazzone A, Catalani M, Costanzo M, Drusian A, Mandoli A, Russo S, Guarini E, Vesperini GEvaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placeboJ Int Med Res.(1990 Sep-Oct)
    26. Boron - Pietrzkowski Z, Phelan MJ, Keller R, Shu C, Argumedo R, Reyes-Izquierdo TShort-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical studyClin Interv Aging.(2014 Jun 5)
    27. Type-II Collagen - Lugo JP, Saiyed ZM, Lau FC, Molina JP, Pakdaman MN, Shamie AN, Udani JKUndenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteersJ Int Soc Sports Nutr.(2013 Oct 24)
    28. Rhodiola Rosea - Punja S, Shamseer L, Olson K, Vohra SRhodiola rosea for mental and physical fatigue in nursing students: a randomized controlled trialPLoS One.(2014 Sep 30)
    29. Ashwagandha - Ramakanth GS, Uday Kumar C, Kishan PV, Usharani PA randomized, double blind placebo controlled study of efficacy and tolerability of Withaina somnifera extracts in knee joint painJ Ayurveda Integr Med.(2016 Jul - Sep)
    30. Peppermint - Shavakhi A, Ardestani SK, Taki M, Goli M, Keshteli AHPremedication with peppermint oil capsules in colonoscopy: a double blind placebo-controlled randomized trial studyActa Gastroenterol Belg.(2012 Sep)
    31. Glucosamine - McAlindon T, Formica M, LaValley M, Lehmer M, Kabbara KEffectiveness of glucosamine for symptoms of knee osteoarthritis: results from an internet-based randomized double-blind controlled trialAm J Med.(2004 Nov 1)
    32. Rose Hip - K Winther, E Rein, A KharazmiThe anti-inflammatory properties of rose-hipInflammopharmacology.(1999)
    33. Curcumin - Shep D, Khanwelkar C, Gade P, Karad SSafety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm studyTrials.(2019 Apr 11)
    34. Cannabidiol (CBD) - Cuñetti L, Manzo L, Peyraube R, Arnaiz J, Curi L, Orihuela SChronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in UruguayTransplant Proc.(2018 Mar)
    35. Coenzyme Q10 - Mario D Cordero, Elísabet Alcocer-Gómez, Manuel de Miguel, Ognjen Culic, Angel M Carrión, José Miguel Alvarez-Suarez, Pedro Bullón, Maurizio Battino, Ana Fernández-Rodríguez, José Antonio Sánchez-AlcazarCan coenzyme q10 improve clinical and molecular parameters in fibromyalgia?Antioxid Redox Signal.(2013 Oct 20)
    36. Cannabis - Aron H Lichtman, Eberhard Albert Lux, Robert McQuade, Sandro Rossetti, Raymond Sanchez, Wei Sun, Stephen Wright, Elena Kornyeyeva, Marie T FallonResults of a Double-Blind, Randomized, Placebo-Controlled Study of Nabiximols Oromucosal Spray as an Adjunctive Therapy in Advanced Cancer Patients with Chronic Uncontrolled PainJ Pain Symptom Manage.(2018 Feb)
    37. Creatine - Avi Leader, Daniella Amital, Alan Rubinow, Howard AmitalAn open-label study adding creatine monohydrate to ongoing medical regimens in patients with the fibromyalgia syndromeAnn N Y Acad Sci.(2009 Sep)
    38. Cannabis - Kraft B, Frickey NA, Kaufmann RM, Reif M, Frey R, Gustorff B, Kress HGLack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteersAnesthesiology.(2008 Jul)
    39. S-adenosylmethionine - Caruso I, Pietrogrande VItalian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint diseaseAm J Med.(1987 Nov 20)
    40. Cannabis - Marie T Fallon, Eberhard Albert Lux, Robert McQuade, Sandro Rossetti, Raymond Sanchez, Wei Sun, Stephen Wright, Aron H Lichtman, Elena KornyeyevaSativex oromucosal spray as adjunctive therapy in advanced cancer patients with chronic pain unalleviated by optimized opioid therapy: two double-blind, randomized, placebo-controlled phase 3 studiesBr J Pain.(2017 Aug)
    41. Rose Hip - Willich SN, Rossnagel K, Roll S, Wagner A, Mune O, Erlendson J, Kharazmi A, Sörensen H, Winther KRose hip herbal remedy in patients with rheumatoid arthritis - a randomised controlled trialPhytomedicine.(2010 Feb)
    42. Cannabis - Wallace M, Schulteis G, Atkinson JH, Wolfson T, Lazzaretto D, Bentley H, Gouaux B, Abramson IDose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteersAnesthesiology.(2007 Nov)
    43. Cannabis - Martín-Sánchez E, Furukawa TA, Taylor J, Martin JLSystematic review and meta-analysis of cannabis treatment for chronic painPain Med.(2009 Nov)
    44. Cannabis - Lee MC, Ploner M, Wiech K, Bingel U, Wanigasekera V, Brooks J, Menon DK, Tracey IAmygdala activity contributes to the dissociative effect of cannabis on pain perceptionPain.(2013 Jan)
    45. Cannabidiol (CBD) - Palmieri B, Laurino C, Vadalà MShort-Term Efficacy of CBD-Enriched Hemp Oil in Girls with Dysautonomic Syndrome after Human Papillomavirus VaccinationIsr Med Assoc J.(2017 Feb)
    46. Curcumin - Amalraj A, Varma K, Jacob J, Divya C, Kunnumakkara AB, Stohs SJ, Gopi SA Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group StudyJ Med Food.(2017 Oct)
    47. Ashwagandha - Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KIEffect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patientsIntegr Cancer Ther.(2013 Jul)
    48. Type-II Collagen - Trentham DE, Dynesius-Trentham RA, Orav EJ, Combitchi D, Lorenzo C, Sewell KL, Hafler DA, Weiner HLEffects of oral administration of type II collagen on rheumatoid arthritisScience.(1993 Sep 24)
    49. Curcumin - Agarwal KA, Tripathi CD, Agarwal BB, Saluja SEfficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled studySurg Endosc.(2011 Dec)
    50. Rose Hip - Kirkeskov B, Christensen R, Bügel S, Bliddal H, Danneskiold-Samsøe B, Christensen LP, Andersen JRThe effects of rose hip (Rosa canina) on plasma antioxidative activity and C-reactive protein in patients with rheumatoid arthritis and normal controls: a prospective cohort studyPhytomedicine.(2011 Aug 15)
    51. Glucosamine - Vlad SC, LaValley MP, McAlindon TE, Felson DTGlucosamine for pain in osteoarthritis: why do trial results differArthritis Rheum.(2007 Jul)
    52. Coenzyme Q10 - Sawaddiruk P, Apaijai N, Paiboonworachat S, Kaewchur T, Kasitanon N, Jaiwongkam T, Kerdphoo S, Chattipakorn N, Chattipakorn SCCoenzyme Q10 supplementation alleviates pain in pregabalin-treated fibromyalgia patients via reducing brain activity and mitochondrial dysfunctionFree Radic Res.(2019 Aug)
    53. Curcumin - Chandran B, Goel AA randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritisPhytother Res.(2012 Nov)
    54. Serrapeptase - G Bracale, L Selvetella[Clinical study of the efficacy of and tolerance to seaprose S in inflammatory venous disease. Controlled study versus serratio-peptidase]Minerva Cardioangiol.(1996 Oct)
    55. Curcumin - Panahi Y, Rahimnia AR, Sharafi M, Alishiri G, Saburi A, Sahebkar ACurcuminoid treatment for knee osteoarthritis: a randomized double-blind placebo-controlled trialPhytother Res.(2014 Nov)
    56. L-Carnitine - Aida Malek Mahdavi, Reza Mahdavi, Sousan KolahiEffects of l-Carnitine Supplementation on Serum Inflammatory Factors and Matrix Metalloproteinase Enzymes in Females with Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Pilot StudyJ Am Coll Nutr.(Sep-Oct 2016)
    57. Microlactin - Colker CM, Swain M, Lynch L, Gingerich DAEffects of a milk-based bioactive micronutrient beverage on pain symptoms and activity of adults with osteoarthritis: a double-blind, placebo-controlled clinical evaluationNutrition.(2002 May)
    58. L-Carnitine - Kolahi S, et alEffect of l-carnitine supplementation on clinical symptoms in women with osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trialEur J Integr Med.()
    59. S-adenosylmethionine - Wadie I Najm, Sibylle Reinsch, Fred Hoehler, Jerome S Tobis, Phillip W HarveyS-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]BMC Musculoskelet Disord.(2004 Feb 26)
    60. Curcumin - Madhu K, Chanda K, Saji MJSafety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trialInflammopharmacology.(2013 Apr)
    61. Binaural Beats - Alessandro Tani, Guido Vagheggini, Francesca Moretti, Valentina Del Colombo, Joerg Lehle, Serena Campana, Angelo Labate, Francesco TomaiuoloBinaural Beats Reduce Postoperative Morphine Consumption in Older adults After Total Knee Replacement SurgeryAltern Ther Health Med.(2020 May 15)
    62. Valerian - Mirabi P, Dolatian M, Mojab F, Majd HAEffects of valerian on the severity and systemic manifestations of dysmenorrheaInt J Gynaecol Obstet.(2011 Dec)
    63. Curcumin - Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, Togni S, Appendino GEfficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patientsAltern Med Rev.(2010 Dec)
    64. Glucosamine - Noack W, Fischer M, Förster KK, Rovati LC, Setnikar IGlucosamine sulfate in osteoarthritis of the kneeOsteoarthritis Cartilage.(1994 Mar)
    65. Cannabidiol (CBD) - Wade DT, Robson P, House H, Makela P, Aram JA preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptomsClin Rehabil.(2003 Feb)
    66. Curcumin - Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech SEfficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter studyClin Interv Aging.(2014 Mar 20)
    67. Curcumin - Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, Togni S, Appendino GProduct-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritisPanminerva Med.(2010 Jun)
    68. Cannabis - Russell K Portenoy, Elena Doina Ganae-Motan, Silvia Allende, Ronald Yanagihara, Lauren Shaiova, Sharon Weinstein, Robert McQuade, Stephen Wright, Marie T FallonNabiximols for opioid-treated cancer patients with poorly-controlled chronic pain: a randomized, placebo-controlled, graded-dose trialJ Pain.(2012 May)
    69. Binaural Beats - Donna D ZampiEfficacy of Theta Binaural Beats for the Treatment of Chronic PainAltern Ther Health Med.(Jan-Feb 2016)
    70. PQQ - Masahiko Nakano, Tetsuro Yamamoto, Hisayoshi Okamura, Akira Tsuda, Yasuyuki KowatariEffects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and SleepFunctional Foods in Health and Disease.()
    71. Horse Chestnut - Pittler MH, Ernst EHorse chestnut seed extract for chronic venous insufficiencyCochrane Database Syst Rev.(2006 Jan 25)
    72. Glucosamine - Herrero-Beaumont G, Ivorra JA, Del Carmen Trabado M, Blanco FJ, Benito P, Martín-Mola E, Paulino J, Marenco JL, Porto A, Laffon A, Araújo D, Figueroa M, Branco JGlucosamine sulfate in the treatment of knee osteoarthritis symptoms: a randomized, double-blind, placebo-controlled study using acetaminophen as a side comparatorArthritis Rheum.(2007 Feb)
    73. Type-II Collagen - Barnett ML, Kremer JM, St Clair EW, Clegg DO, Furst D, Weisman M, Fletcher MJ, Chasan-Taber S, Finger E, Morales A, Le CH, Trentham DETreatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trialArthritis Rheum.(1998 Feb)
    74. Curcumin - Pinsornsak P, Niempoog SThe efficacy of Curcuma Longa L. extract as an adjuvant therapy in primary knee osteoarthritis: a randomized control trialJ Med Assoc Thai.(2012 Jan)
    75. Cissus Quadrangularis - Richard J Bloomer, Tyler M Farney, Cameron G McCarthy, Sang-Rok LeeCissus quadrangularis reduces joint pain in exercise-trained men: a pilot studyPhys Sportsmed.(2013 Sep)
    76. Curcumin - Panda SK, Nirvanashetty S, Parachur VA, Mohanty N, Swain TA Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OABiomed Res Int.(2018 Oct 25)
    77. Glucosamine - Richy F, Bruyere O, Ethgen O, Cucherat M, Henrotin Y, Reginster JYStructural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysisArch Intern Med.(2003 Jul 14)
    78. MSM - Debbi EM, Agar G, Fichman G, Ziv YB, Kardosh R, Halperin N, Elbaz A, Beer Y, Debi REfficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled studyBMC Complement Altern Med.(2011 Jun 27)
    79. Saffron - Mansoor Shakiba, Ehsan Moazen-Zadeh, Ahmad Ali Noorbala, Morteza Jafarinia, Parisa Divsalar, Ladan Kashani, Nazila Shahmansouri, Abbas Tafakhori, Hannaneh Bayat, Shahin AkhondzadehSaffron ( Crocus sativus) versus duloxetine for treatment of patients with fibromyalgia: A randomized double-blind clinical trialAvicenna J Phytomed.(Nov-Dec 2018)
    80. Tart Cherry Juice - Shenouda M, Copley R, Pacioles T, Lebowicz Y, Jamil M, Akpanudo S, Tirona MTEffect of Tart Cherry on Aromatase Inhibitor-Induced Arthralgia (AIA) in Nonmetastatic Hormone-Positive Breast Cancer Patients: A Randomized Double-Blind Placebo-Controlled Trial.Clin Breast Cancer.(2022-Jan)
    81. Magnesium - Macian N, Dualé C, Voute M, Leray V, Courrent M, Bodé P, Giron F, Sonneville S, Bernard L, Joanny F, Menard K, Ducheix G, Pereira B, Pickering GShort-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial.Nutrients.(2022-May-17)
    82. Magnesium - Hashemian M, Mirkheshti A, Mirafzal A, Ahmadipour H, Nasehabad MAThe effect of preoperative oral magnesium oxide on the severity of postoperative pain among women undergoing hysterectomy.Ir J Med Sci.(2022-Dec)
    83. Aloe Vera - Zou H, Liu Z, Wang Z, Fang JEffects of Aloe Vera in the Treatment of Oral Ulcers: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Oral Health Prev Dent.(2022-Dec-12)
    84. Aloe Vera - Gok Metin Z, Helvaci A, Gulbahar Eren MEffects of Aloe vera in adults with mucocutaneous problems: A systematic review and meta-analysis.J Adv Nurs.(2021-Mar)
    85. Yoga - Tsai IC, Hsu CW, Chang CH, Lei WT, Tseng PT, Chang KVComparative Effectiveness of Different Exercises for Reducing Pain Intensity in Primary Dysmenorrhea: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.Sports Med Open.(2024 May 30)
    86. Progressive Muscle Relaxation - Mashhadi-Naser S, Shirvani S, Vasli PA randomized controlled trial to evaluate the progressive muscle relaxation technique in hip fracture patients.Sci Rep.(2024 Jun 12)
    87. Resveratrol - Nguyen C, Coudeyre E, Boutron I, Baron G, Daste C, Lefèvre-Colau MM, Sellam J, Zauderer J, Berenbaum F, Rannou FOral resveratrol in adults with knee osteoarthritis: A randomized placebo-controlled trial (ARTHROL).PLoS Med.(2024 Aug)