Liver Enzymes

    Last Updated: October 13, 2024

    Liver enzymes are used as biomarkers to test the toxicity of a supplement and are elevated in case of fatty or cirrhotic liver. Lower blood levels are thought to reflect less-damaged liver cells.

    Liver Enzymes falls under the Liver Health category.

    44,735 participants in 217 trials

    Summary

    The most common liver enzymes are aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transpeptidase (GGT).

    Examine Database: Liver Enzymes

    InterventionGradeEffectDetail
    Curcumin
    C
    Vitamin E
    C
    Black seed
    B
    Saffron
    Astaxanthin
    TUDCA
    Conjugated Linoleic Acid
    Chlorella
    Creatine
    Mediterranean Diet
    N-Acetylcysteine
    L-Carnitine
    Spirulina
    Betaine
    Kefir
    S-adenosylmethionine
    Rose Hip
    Lactobacillus Reuteri
    Resveratrol
    Chromium
    Tetradecyl Thioacetic Acid
    Coenzyme Q10
    Silymarin
    Eleuthero
    Panax Ginseng (Korean Ginseng)
    Kava
    Olive Leaf Extract
    Ashwagandha
    HMB
    Garlic
    Bitter Cucumber
    Citrulline
    Ketogenic Diet
    Intermittent fasting (IF)
    Synbiotics
    Tongkat Ali
    Rhodiola Rosea
    Black Cohosh
    Cinnamon
    Kutki
    Bulbine Natalensis
    Bushman's hat
    Terminalia Arjuna
    Jiaogulan
    Dill
    King of Bitters
    Whey Protein
    Theanine
    Phosphatidylserine
    Glutamine
    Leucine
    Niacin (Vitamin B3)
    Vitamin C
    Vitamin D
    Hesperidin
    Pycnogenol
    Red Clover Extract
    Pterostilbene
    Brown Seaweed Extract
    Boron
    Melatonin
    DHEA
    Ecdysteroids
    Perilla
    Fish Oil
    Green Coffee Extract
    Korean black raspberry
    Tribulus Terrestris
    Royal Jelly
    Reishi
    Cordyceps
    Roselle
    Artichoke Extract
    Cocoa Extract
    Nattokinase
    PQQ
    Inositol
    Honey
    Nicotinamide Mononucleotide
    Probiotics
    Propolis
    Sumac

    Research FeedRead all studies

    Examine Database References

    1. TUDCA - Larghi A, Crosignani A, Battezzati PM, De Valle G, Allocca M, Invernizzi P, Zuin M, Podda MUrsodeoxycholic and tauro-ursodeoxycholic acids for the treatment of primary biliary cirrhosis: a pilot crossover studyAliment Pharmacol Ther.(1997 Apr)
    2. Kutki - Vaidya AB, Antarkar DS, Doshi JC, Bhatt AD, Ramesh V, Vora PV, Perissond D, Baxi AJ, Kale PMPicrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studiesJ Postgrad Med.(1996 Oct-Dec)
    3. Brown Seaweed Extract - Abidov M, Ramazanov Z, Seifulla R, Grachev SThe effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fatDiabetes Obes Metab.(2010 Jan)
    4. Pterostilbene - Riche DM, McEwen CL, Riche KD, Sherman JJ, Wofford MR, Deschamp D, Griswold MAnalysis of safety from a human clinical trial with pterostilbeneJ Toxicol.(2013)
    5. Olive Leaf Extract - Susalit E, Agus N, Effendi I, Tjandrawinata RR, Nofiarny D, Perrinjaquet-Moccetti T, Verbruggen MOlive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with CaptoprilPhytomedicine.(2011 Feb 15)
    6. Conjugated Linoleic Acid - A J Wanders, L Leder, J D Banga, M B Katan, I A BrouwerA high intake of conjugated linoleic acid does not affect liver and kidney function tests in healthy human subjectsFood Chem Toxicol.(2010 Feb)
    7. Niacin (Vitamin B3) - Westphal S, Borucki K, Taneva E, Makarova R, Luley CExtended-release niacin raises adiponectin and leptinAtherosclerosis.(2007 Aug)
    8. TUDCA - Crosignani A, Battezzati PM, Setchell KD, Invernizzi P, Covini G, Zuin M, Podda MTauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response studyDig Dis Sci.(1996 Apr)
    9. Conjugated Linoleic Acid - Iwata T, Kamegai T, Yamauchi-Sato Y, Ogawa A, Kasai M, Aoyama T, Kondo KSafety of dietary conjugated linoleic acid (CLA) in a 12-weeks trial in healthy overweight Japanese male volunteersJ Oleo Sci.(2007)
    10. Nattokinase - Yang NC, Chou CW, Chen CY, Hwang KL, Yang YCCombined nattokinase with red yeast rice but not nattokinase alone has potent effects on blood lipids in human subjects with hyperlipidemia.Asia Pac J Clin Nutr.(2009)
    11. Ashwagandha - Raut AA, Rege NN, Tadvi FM, Solanki PV, Kene KR, Shirolkar SG, Pandey SN, Vaidya RA, Vaidya ABExploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteersJ Ayurveda Integr Med.(2012 Jul)
    12. HMB - Richard B. Kreider, Maria Pontes Ferreira, Michael Greenwood, M. Wilson, Pamela Grindstaff, Steven Plisk, Jeff Reinardy, Edward Cantler, and Anthony L. AmaldaEffects of Calcium β-HMB Supplementation During Training on Markers of Catabolism, Body Composition, Strength and Sprint PerformanceJournal of Exercise Physiology.()
    13. Bushman's hat - Blom WA, Abrahamse SL, Bradford R, Duchateau GS, Theis W, Orsi A, Ward CL, Mela DJEffects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women: a randomized controlled trialAm J Clin Nutr.(2011 Nov)
    14. Korean black raspberry - Ji Eun Lee, Eunkyo Park, Jung Eun Lee, Joong Hyuck Auh, Hyung-Kyoon Choi, Jaehwi Lee, Soomuk Cho, Jung-Hyun KimEffects of a Rubus coreanus Miquel supplement on plasma antioxidant capacity in healthy Korean menNutr Res Pract.(2011 Oct)
    15. Black seed - Datau EA, Wardhana, Surachmanto EE, Pandelaki K, Langi JA, FiasEfficacy of Nigella sativa on serum free testosterone and metabolic disturbances in central obese maleActa Med Indones.(2010 Jul)
    16. Spirulina - Patricia V Torres-Duran, Aldo Ferreira-Hermosillo, Marco A Juarez-OropezaAntihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary reportLipids Health Dis.(2007 Nov 26)
    17. Panax Ginseng (Korean Ginseng) - Meegun Hong, Yoon Hyeong Lee, Seungwoo Kim, Ki Tae Suk, Chang Seok Bang, Jai Hoon Yoon, Gwang Ho Baik, Dong Joon Kim, Myong Jo KimAnti-inflammatory and antifatigue effect of Korean Red Ginseng in patients with nonalcoholic fatty liver diseaseJ Ginseng Res.(2016 Jul)
    18. Bulbine Natalensis - Jennifer E Hofheins, Scott M Habowski, Tim N Ziegenfuss, and Hector L LopezShort term safety of bulbine natalensis supplementation in healthy menJISSN.()
    19. Ecdysteroids - Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RBEffects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained malesJ Int Soc Sports Nutr.(2006 Dec 13)
    20. Chromium - Lai MHAntioxidant effects and insulin resistance improvement of chromium combined with vitamin C and e supplementation for type 2 diabetes mellitusJ Clin Biochem Nutr.(2008 Nov)
    21. Cocoa Extract - Di Renzo L, Rizzo M, Sarlo F, Colica C, Iacopino L, Domino E, Sergi D, De Lorenzo AEffects of dark chocolate in a population of normal weight obese women: a pilot studyEur Rev Med Pharmacol Sci.(2013 Aug)
    22. L-Carnitine - S Georgala, K H Schulpis, C Georgala, T MichasL-carnitine supplementation in patients with cystic acne on isotretinoin therapyJ Eur Acad Dermatol Venereol.(1999 Nov)
    23. Curcumin - Jazayeri-Tehrani SA, Rezayat SM, Mansouri S, Qorbani M, Alavian SM, Daneshi-Maskooni M, Hosseinzadeh-Attar MJNano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trialNutr Metab (Lond).(2019 Jan 28)
    24. Rose Hip - Andersson U, Berger K, Högberg A, Landin-Olsson M, Holm CEffects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr.(2012 May)
    25. Panax Ginseng (Korean Ginseng) - Yi-Ming Chen, I-Lin Wang, Shu Zhou, Tsung-Yu Tsai, Yen-Shuo Chiu, Wan-Chun ChiuSix weeks of Jilin ginseng root supplementation attenuates drop jump-related muscle injury markers in healthy female college studentsFood Funct.(2021 Mar 1)
    26. Tetradecyl Thioacetic Acid - Reidar J Pettersen, Mohamed Salem, Jon Skorve, Rune J Ulvik, Rolf K Berge, Jan Erik NordrehaugPharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 studyJ Cardiovasc Pharmacol.(2008 Apr)
    27. L-Carnitine - Salvatore Benvenga, Antonino Amato, Menotti Calvani, Francesco TrimarchiEffects of carnitine on thyroid hormone actionAnn N Y Acad Sci.(2004 Nov)
    28. Citrulline - Paul Hwang, Flor E Morales Marroquín, Josh Gann, Tom Andre, Sarah McKinley-Barnard, Caelin Kim, Masahiko Morita, Darryn S WilloughbyEight weeks of resistance training in conjunction with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained malesJ Int Soc Sports Nutr.(2018 Jun 27)
    29. Lactobacillus Reuteri - Jones ML, Martoni CJ, Di Pietro E, Simon RR, Prakash SEvaluation of clinical safety and tolerance of a Lactobacillus reuteri NCIMB 30242 supplement capsule: a randomized control trialRegul Toxicol Pharmacol.(2012 Jul)
    30. Vitamin E - P M Farrell, J G BieriMegavitamin E supplementation in manAm J Clin Nutr.(1975 Dec)
    31. Kefir - Ali Kudret Adiloğlu, Nurettin Gönülateş, Mehmet Işler, Altuğ Senol[The effect of kefir consumption on human immune system: a cytokine study]Mikrobiyol Bul.(2013 Apr)
    32. Melatonin - Gonciarz M, Bielański W, Partyka R, Brzozowski T, Konturek PC, Eszyk J, Celiński K, Reiter RJ, Konturek SJPlasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatoninJ Pineal Res.(2012 Jun 13)
    33. Red Clover Extract - Baber RJ, Templeman C, Morton T, Kelly GE, West LRandomized placebo-controlled trial of an isoflavone supplement and menopausal symptoms in womenClimacteric.(1999 Jun)
    34. Kefir - Ezgi Bellikci-Koyu, Banu Pınar Sarer-Yurekli, Yakut Akyon, Fadime Aydin-Kose, Cem Karagozlu, Ahmet Gokhan Ozgen, Annika Brinkmann, Andreas Nitsche, Koray Ergunay, Engin Yilmaz, Zehra BuyuktuncerEffects of Regular Kefir Consumption on Gut Microbiota in Patients with Metabolic Syndrome: A Parallel-Group, Randomized, Controlled StudyNutrients.(2019 Sep 4)
    35. Curcumin - Na LX, Li Y, Pan HZ, Zhou XL, Sun DJ, Meng M, Li XX, Sun CHCurcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trialMol Nutr Food Res.(2013 Sep)
    36. S-adenosylmethionine - Medici V, Virata MC, Peerson JM, Stabler SP, French SW, Gregory JF 3rd, Albanese A, Bowlus CL, Devaraj S, Panacek EA, Richards JR, Halsted CHS-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trialAlcohol Clin Exp Res.(2011 Nov)
    37. L-Carnitine - Alavinejad P, et alEvaluation of L-Carnitine Efficacy in the Treatment of Non-Alcoholic Fatty Liver Disease among Diabetic Patients: A Randomized Double Blind Pilot StudyJ Gastroenterol Hepatol.()
    38. Vitamin D - David D Chandy, Jahnavi Kare, Shakal N Singh, Anjoo Agarwal, Vinita Das, Urmila Singh, V Ramesh, Vijayalakshmi BhatiaEffect of vitamin D supplementation, directly or via breast milk for term infants, on serum 25 hydroxyvitamin D and related biochemistry, and propensity to infection: a randomised placebo-controlled trialBr J Nutr.(2016 Jul)
    39. Rose Hip - Nagatomo A, Nishida N, Fukuhara I, Noro A, Kozai Y, Sato H, Matsuura YDaily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trialDiabetes Metab Syndr Obes.(2015 Mar 6)
    40. Kefir - GÖLÜNÜK, S et alEffects of traditional fermented beverages on some blood parameters in aerobic exercises.Biomedical Research.()
    41. Coenzyme Q10 - Serag H, El Wakeel L, Adly ACoenzyme Q10 administration has no effect on sICAM-1 and metabolic parameters of pediatrics with type 1 diabetes mellitusInt J Vitam Nutr Res.(2020 Jan 16)
    42. L-Carnitine - Esmaeil Yousefi Rad, Elham Eslampour, Ebrahim Falahi, Mahnaz Mardani, Azita Hekmatdoost, Omid Asbaghi, Somayeh SabooriEffects of carnitine supplementation on liver aminotransferase enzymes: A systematic review and meta-analysis of randomized controlled clinical trialsIndian J Gastroenterol.(2019 Dec)
    43. Reishi - Wachtel-Galor S, Tomlinson B, Benzie IFGanoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation studyBr J Nutr.(2004 Feb)
    44. Astaxanthin - Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi YProtective effects of astaxanthin on skin deteriorationJ Clin Biochem Nutr.(2017 Jul)
    45. Kefir - Ghizi ACdS et alKefir improves blood parameters and reduces cardiovascular risks in patients with metabolic syndromePharmaNutrition.()
    46. Curcumin - Funamoto M, Sunagawa Y, Katanasaka Y, Miyazaki Y, Imaizumi A, Kakeya H, Yamakage H, Satoh-Asahara N, Komiyama M, Wada H, Hasegawa K, Morimoto THighly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPDInt J Chron Obstruct Pulmon Dis.(2016 Aug 26)
    47. S-adenosylmethionine - Thompson MA, Bauer BA, Loehrer LL, Cha SS, Mandrekar JN, Sood A, Wahner-Roedler DLDietary supplement S-adenosyl-L-methionine (AdoMet) effects on plasma homocysteine levels in healthy human subjects: a double-blind, placebo-controlled, randomized clinical trialJ Altern Complement Med.(2009 May)
    48. Creatine - Manjarrez-Montes de Oca R, Farfán-González F, Camarillo-Romero S, Tlatempa-Sotelo P, Francisco-Argüelles C, Kormanowski A, González-Gallego J, Alvear-Ordenes IEffects of creatine supplementation in taekwondo practitionersNutr Hosp.(2013 Mar-Apr)
    49. Citrulline - Sureda A, Cordova A, Ferrer MD, Tauler P, Perez G, Tur JA, Pons AEffects of L-citrulline oral supplementation on polymorphonuclear neutrophils oxidative burst and nitric oxide production after exerciseFree Radic Res.(2009 Sep)
    50. Astaxanthin - Nakagawa K, Kiko T, Miyazawa T, Carpentero Burdeos G, Kimura F, Satoh A, Miyazawa TAntioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytesBr J Nutr.(2011 Jun)
    51. Conjugated Linoleic Acid - Gaullier JM, Halse J, Høye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen OSupplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humansJ Nutr.(2005 Apr)
    52. L-Carnitine - Jee Hyun An, Yoon Jung Kim, Kyeong Jin Kim, Sun Hwa Kim, Nam Hoon Kim, Hee Young Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon KimL-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trialEndocr J.(2016 Oct 29)
    53. L-Carnitine - Malaguarnera M, Bella R, Vacante M, Giordano M, Malaguarnera G, Gargante MP, Motta M, Mistretta A, Rampello L, Pennisi GAcetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathyScand J Gastroenterol.(2011 Jun)
    54. Inositol - Joseph Levine, Mirtha Gonsalves, Izak Babur, Shaul Stier, Avner Elizur, Ora Kofman, R. H. BelmakerInositol 6 g daily may be effective in depression but not in schizophreniaHuman Psychopharmacology: Clinical and Experimental.()
    55. Creatine - Groeneveld GJ, Veldink JH, van der Tweel I, Kalmijn S, Beijer C, de Visser M, Wokke JH, Franssen H, van den Berg LHA randomized sequential trial of creatine in amyotrophic lateral sclerosisAnn Neurol.(2003 Apr)
    56. Betaine - Schwab U, Alfthan G, Aro A, Uusitupa MLong-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjectsEur J Clin Nutr.(2011 Jan)
    57. Curcumin - Chuengsamarn S, Rattanamongkolgul S, Phonrat B, Tungtrongchitr R, Jirawatnotai SReduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trialJ Nutr Biochem.(2014 Feb)
    58. TUDCA - Crosignani A, Budillon G, Cimino L, Del Vecchio Blanco C, Loguercio C, Ideo G, Raimondo G, Stabilini R, Podda MTauroursodeoxycholic acid for the treatment of HCV-related chronic hepatitis: a multicenter placebo-controlled studyHepatogastroenterology.(1998 Sep-Oct)
    59. Black seed - Qidwai W, Hamza HB, Qureshi R, Gilani AEffectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trialJ Altern Complement Med.(2009 Jun)
    60. Astaxanthin - Spiller GA, Dewell ASafety of an astaxanthin-rich Haematococcus pluvialis algal extract: a randomized clinical trialJ Med Food.(2003 Spring)
    61. Saffron - Mansoori P, et alA Randomized, Double-blind, Placebo - controlled Study of Safety of the Adjunctive Saffron on Sexual Dysfunction Induced by a Selective Serotonin Reuptake InhibitorJ Med Plant .()
    62. Kava - Gastpar M, Klimm HDTreatment of anxiety, tension and restlessness states with Kava special extract WS 1490 in general practice: a randomized placebo-controlled double-blind multicenter trialPhytomedicine.(2003 Nov)
    63. Olive Leaf Extract - de Bock M, Derraik JG, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WSOlive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover TrialPLoS One.(2013)
    64. TUDCA - Panella C, Ierardi E, De Marco MF, Barone M, Guglielmi FW, Polimeno L, Francavilla ADoes tauroursodeoxycholic acid (TUDCA) treatment increase hepatocyte proliferation in patients with chronic liver diseaseItal J Gastroenterol.(1995 Jun)
    65. Curcumin - Panahi Y, Khalili N, Sahebi E, Namazi S, Simental-Mendía LE, Majeed M, Sahebkar AEffects of Curcuminoids Plus Piperine on Glycemic, Hepatic and Inflammatory Biomarkers in Patients with Type 2 Diabetes Mellitus: A Randomized Double-Blind Placebo-Controlled TrialDrug Res (Stuttg).(2018 Jul)
    66. Curcumin - Yang H, Xu W, Zhou Z, Liu J, Li X, Chen L, Weng J, Yu ZCurcumin attenuates urinary excretion of albumin in type II diabetic patients with enhancing nuclear factor erythroid-derived 2-like 2 (Nrf2) system and repressing inflammatory signaling efficaciesExp Clin Endocrinol Diabetes.(2015 Jun)
    67. L-Carnitine - Bruls Y, et alCarnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trialEBioMedicine.()
    68. Bitter Cucumber - Rahbar AR, Nabipour IThe hypolipidemic effect of Citrullus colocynthis on patients with hyperlipidemiaPak J Biol Sci.(2010 Dec 15)
    69. Vitamin E - T Hasegawa, M Yoneda, K Nakamura, I Makino, A TeranoPlasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot studyAliment Pharmacol Ther.(2001 Oct)
    70. Curcumin - Navekar R, Rafraf M, Ghaffari A, Asghari-Jafarabadi M, Khoshbaten MTurmeric Supplementation Improves Serum Glucose Indices and Leptin Levels in Patients with Nonalcoholic Fatty Liver DiseasesJ Am Coll Nutr.(2017 May-Jun)
    71. Bitter Cucumber - Huseini HF, Darvishzadeh F, Heshmat R, Jafariazar Z, Raza M, Larijani BThe clinical investigation of Citrullus colocynthis (L.) schrad fruit in treatment of Type II diabetic patients: a randomized, double blind, placebo-controlled clinical trialPhytother Res.(2009 Aug)
    72. Astaxanthin - Coombes JS, Sharman JE, Fassett RGAstaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial)Am J Clin Nutr.(2016 Jan)
    73. Tetradecyl Thioacetic Acid - Fredriksen J, Ueland T, Dyrøy E, Halvorsen B, Melby K, Melbye L, Skalhegg BS, Bohov P, Skorve J, Berge RK, Aukrust P, Frøland SSLipid-lowering and anti-inflammatory effects of tetradecylthioacetic acid in HIV-infected patients on highly active antiretroviral therapyEur J Clin Invest.(2004 Oct)
    74. L-Carnitine - Mohamad Hosein Somi, Ebrahim Fatahi, Jafar Panahi, Mohamad Reza Havasian, Arezo JudakiData from a randomized and controlled trial of LCarnitine prescription for the treatment for Non- Alcoholic Fatty Liver DiseaseBioinformation.(2014 Sep 30)
    75. Vitamin C - Mason SA, Rasmussen B, van Loon LJC, Salmon J, Wadley GDAscorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: Findings of a randomized cross-over trialDiabetes Obes Metab.(2019 Mar)
    76. Conjugated Linoleic Acid - Whigham LD, O'Shea M, Mohede IC, Walaski HP, Atkinson RLSafety profile of conjugated linoleic acid in a 12-month trial in obese humansFood Chem Toxicol.(2004 Oct)
    77. Spirulina - Elias E Mazokopakis, Maria G Papadomanolaki, Andreas A Fousteris, Dimitrios A Kotsiris, Ioannis M Lampadakis, Emmanuel S GanotakisThe hepatoprotective and hypolipidemic effects of Spirulina ( Arthrospira platensis) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot studyAnn Gastroenterol.(2014)
    78. Vitamin E - Miwa Kawanaka, Sabina Mahmood, Gouichi Niiyama, Akiyoshi Izumi, Ayumi Kamei, Hideji Ikeda, Mitsuhiko Suehiro, Kazumi Togawa, Takayo Sasagawa, Misako Okita, Hajime Nakamura, Junji Yodoi, Gotaro YamadaControl of oxidative stress and reduction in biochemical markers by Vitamin E treatment in patients with nonalcoholic steatohepatitis: a pilot studyHepatology Research.()
    79. Creatine - Schilling BK, Stone MH, Utter A, Kearney JT, Johnson M, Coglianese R, Smith L, O'Bryant HS, Fry AC, Starks M, Keith R, Stone MECreatine supplementation and health variables: a retrospective studyMed Sci Sports Exerc.(2001 Feb)
    80. Garlic - K Rahman, D BillingtonDietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humansJ Nutr.(2000 Nov)
    81. Astaxanthin - Chen JT, Kotani KEffects of Astaxanthin on Liver and Leukocyte Parameters in Healthy Climacteric Women: Preliminary DataJ Med Food.(2017 Jul)
    82. Boron - Nielsen F, Penland JBoron supplementation of peri‐menopausal women affects boron metabolism and indices associated with macromineral metabolism, hormonal status and immune functionJ Trace Elem Med Biol.()
    83. Curcumin - T Krishnareddy N, Thomas JV, Nair SS, N Mulakal J, Maliakel BP, Krishnakumar IMA Novel Curcumin-Galactomannoside Complex Delivery System Improves Hepatic Function Markers in Chronic Alcoholics: A Double-Blinded, randomized, Placebo-Controlled StudyBiomed Res Int.(2018 Sep 23)
    84. Rose Hip - Kharazmi A, Winther KRose hip inhibits chemotaxis and chemiluminescence of human peripheral blood neutrophils in vitro and reduces certain inflammatory parameters in vivoInflammopharmacology.(1999)
    85. Vitamin E - Sumida Y, Naito Y, Tanaka S, Sakai K, Inada Y, Taketani H, Kanemasa K, Yasui K, Itoh Y, Okanoue T, Yoshikawa TLong-term (>=2 yr) efficacy of vitamin E for non-alcoholic steatohepatitisHepatogastroenterology.(2013 Sep)
    86. Conjugated Linoleic Acid - Smedman A, Vessby B, Basu SIsomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitorClin Sci (Lond).(2004 Jan)
    87. King of Bitters - Calabrese C, Berman SH, Babish JG, Ma X, Shinto L, Dorr M, Wells K, Wenner CA, Standish LJA phase I trial of andrographolide in HIV positive patients and normal volunteersPhytother Res.(2000 Aug)
    88. Garlic - Sobenin IA, Andrianova IV, Demidova ON, Gorchakova T, Orekhov ANLipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized studyJ Atheroscler Thromb.(2008 Dec)
    89. Saffron - Motahareh Hasani, Mahsa Malekahmadi, Gholamreza Rezamand, M Dulce Estêvão, Ana Beatriz Pizarro, Hafez Heydari, Wong Chun Hoong, Omar Ahnaf Arafah, Abdul Rahman Riad Barakeh, Areej Rahman, Mona Saud K Alrashidi, Ahmed Abu-ZaidEffect of saffron supplementation on liver enzymes: A systematic review and meta-analysis of randomized controlled trialsDiabetes Metab Syndr.(2021 Oct 12)
    90. Spirulina - Ferreira-Hermosillo A, Torres-Duran PV, Juarez-Oropeza MAHepatoprotective effects of Spirulina maxima in patients with non-alcoholic fatty liver disease: a case seriesJ Med Case Rep.(2010 Apr 7)
    91. Vitamin E - Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, NASH CRNPioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitisN Engl J Med.(2010 May 6)
    92. Curcumin - Saeede Saadati, Behzad Hatami, Zahra Yari, Mohammad Amin Shahrbaf, Sareh Eghtesad, Asieh Mansour, Hossein Poustchi, Mehdi Hedayati, Morteza Aghajanpoor-Pasha, Amir Sadeghi, Azita HekmatdoostThe effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver diseaseEur J Clin Nutr.(2019 Mar)
    93. Terminalia Arjuna - S Dwivedi, R JauhariBeneficial effects of Terminalia arjuna in coronary artery diseaseIndian Heart J.(Sep-Oct 1997)
    94. PQQ - Harris CB, Chowanadisai W, Mishchuk DO, Satre MA, Slupsky CM, Rucker RBDietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjectsJ Nutr Biochem.(2013 Dec)
    95. Curcumin - Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, Sripradha REfficacy of Turmeric as Adjuvant Therapy in Type 2 Diabetic PatientsIndian J Clin Biochem.(2015 Apr)
    96. Creatine - Tarnopolsky MA, Mahoney DJ, Vajsar J, Rodriguez C, Doherty TJ, Roy BD, Biggar DCreatine monohydrate enhances strength and body composition in Duchenne muscular dystrophyNeurology.(2004 May 25)
    97. Eleuthero - Kuo J, Chen KW, Cheng IS, Tsai PH, Lu YJ, Lee NYThe effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in humanChin J Physiol.(2010 Apr 30)
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    216. TUDCA - Ursodeoxycholic and Tauro-Ursodeoxycholic Acids for the Treatment of Primary Biliary Cirrhosis: A Pilot Crossover Study.()
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