Overview
What is high cholesterol?
What are the main signs and symptoms of high cholesterol?
How is high cholesterol diagnosed?
What are some of the main medical treatments for high cholesterol?
Have any supplements been studied for high cholesterol?
How could diet affect high cholesterol?
Are there any other treatments for high cholesterol?
What causes high cholesterol?
Examine Database: High Cholesterol
Research FeedRead all studies
The benefit of breaking up prolonged sitting after aerobic exercise
In this randomized crossover trial, taking 4-minute walking breaks every hour after aerobic exercise reduced non-HDL cholesterol more than prolonged sitting after aerobic exercise.
Does bergamot extract improve cardiovascular disease risk factors?
Pulses for improving blood lipids: Are some types better than others?
Is glucomannan useful for improving blood lipids?
Does a supplement containing onion and garlic improve blood lipid levels?
Frequently asked questions
Does the DASH diet do anything else besides lower blood pressure?
What exactly should I eat to adhere to the DASH diet?
What other foods are known to impact cholesterol levels and heart health?
Are fully hydrogenated oils a health concern?
Is saturated fat bad for your health?
References
Examine Database References
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- Blood glucose - Saeede Saadati, Behzad Hatami, Zahra Yari, Mohammad Amin Shahrbaf, Sareh Eghtesad, Asieh Mansour, Hossein Poustchi, Mehdi Hedayati, Morteza Aghajanpoor-Pasha, Amir Sadeghi, Azita HekmatdoostThe effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver diseaseEur J Clin Nutr.(2019 Mar)
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- Blood glucose - Ferguson JJA, Stojanovski E, MacDonald-Wicks L, Garg MLCurcumin potentiates cholesterol-lowering effects of phytosterols in hypercholesterolaemic individuals. A randomised controlled trialMetabolism.(2018 May)
- Weight - Mohammadi A, Sahebkar A, Iranshahi M, Amini M, Khojasteh R, Ghayour-Mobarhan M, Ferns GAEffects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trialPhytother Res.(2013 Mar)
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- High-density lipoprotein (HDL) - Baum L, Cheung SK, Mok VC, Lam LC, Leung VP, Hui E, Ng CC, Chow M, Ho PC, Lam S, Woo J, Chiu HF, Goggins W, Zee B, Wong A, Mok H, Cheng WK, Fong C, Lee JS, Chan MH, Szeto SS, Lui VW, Tsoh J, Kwok TC, Chan IH, Lam CWCurcumin effects on blood lipid profile in a 6-month human studyPharmacol Res.(2007 Dec)
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- Blood glucose - Patricia V Torres-Duran, Aldo Ferreira-Hermosillo, Marco A Juarez-OropezaAntihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary reportLipids Health Dis.(2007 Nov 26)
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- Blood glucose - Szulinska M, Gibas-Dorna M, Miller-Kasprzak E, Suliburska J, Miczke A, Walczak-Gałezewska M, Stelmach-Mardas M, Walkowiak J, Bogdanski PSpirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled studyEur Rev Med Pharmacol Sci.(2017 May)
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- High-density lipoprotein (HDL) - Park HJ, Lee YJ, Ryu HK, Kim MH, Chung HW, Kim WYA randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly KoreansAnn Nutr Metab.(2008)
- Blood glucose - Siavash M, Amini MVitamin C may have similar beneficial effects to Gemfibrozil on serum high-density lipoprotein-cholesterol in type 2 diabetic patientsJ Res Pharm Pract.(2014 Jul)
- Blood glucose - Bishop N, Schorah CJ, Wales JKThe effect of vitamin C supplementation on diabetic hyperlipidaemia: a double blind, crossover studyDiabet Med.(1985 Mar)
- Blood glucose - Mahmoudabadi MM, Djalali M, Djazayery SA, Keshavarz SA, Eshraghian MR, Yaraghi AA, Askari G, Ghiasvand R, Zarei MEffects of eicosapentaenoic acid and vitamin C on glycemic indices, blood pressure, and serum lipids in type 2 diabetic Iranian malesJ Res Med Sci.(2011 Mar)
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- Blood glucose - Partsalaki I, Karvela A, Spiliotis BEMetabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescentsJ Pediatr Endocrinol Metab.(2012)
- Blood glucose - Noakes M, Foster PR, Keogh JB, James AP, Mamo JC, Clifton PMComparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular riskNutr Metab (Lond).(2006 Jan 11)
- Blood glucose - Sharman MJ, Gómez AL, Kraemer WJ, Volek JSVery low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight menJ Nutr.(2004 Apr)
- Blood glucose - Hernandez TL, Sutherland JP, Wolfe P, Allian-Sauer M, Capell WH, Talley ND, Wyatt HR, Foster GD, Hill JO, Eckel RHLack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate dietAm J Clin Nutr.(2010 Mar)
- Apolipoprotein A - Joo M, Moon S, Lee YS, Kim MGEffects of very low-carbohydrate ketogenic diets on lipid profiles in normal-weight (body mass index < 25 kg/m2) adults: a meta-analysis.Nutr Rev.(2023-Mar-17)
- Blood glucose - Zhang Y, Li X, Zou D, Liu W, Yang J, Zhu N, Huo L, Wang M, Hong J, Wu P, Ren G, Ning GTreatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberineJ Clin Endocrinol Metab.(2008 Jul)
- High-density lipoprotein (HDL) - Osadnik T, Goławski M, Lewandowski P, Morze J, Osadnik K, Pawlas N, Lejawa M, Jakubiak GK, Mazur A, Schwingschackl L, Gąsior M, Banach MA network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults.Pharmacol Res.(2022-Sep)
- Blood glucose - Spangler L, Newton KM, Grothaus LC, Reed SD, Ehrlich K, LaCroix AZThe effects of black cohosh therapies on lipids, fibrinogen, glucose and insulinMaturitas.(2007 Jun 20)
- Blood glucose - Morgan WA, Raskin P, Rosenstock JA comparison of fish oil or corn oil supplements in hyperlipidemic subjects with NIDDMDiabetes Care.(1995 Jan)
- Blood glucose - Krebs JD, Browning LM, McLean NK, Rothwell JL, Mishra GD, Moore CS, Jebb SAAdditive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic womenInt J Obes (Lond).(2006 Oct)
- Blood glucose - Skulas-Ray AC, Kris-Etherton PM, Harris WS, Vanden Heuvel JP, Wagner PR, West SGDose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemiaAm J Clin Nutr.(2011 Feb)
- Blood glucose - Maki KC, Lawless AL, Kelley KM, Dicklin MR, Schild AL, Rains TMPrescription omega-3-acid ethyl esters reduce fasting and postprandial triglycerides and modestly reduce pancreatic β-cell response in subjects with primary hypertriglyceridemiaProstaglandins Leukot Essent Fatty Acids.(2011 Sep-Oct)
- Blood glucose - Connor WE, Prince MJ, Ullmann D, Riddle M, Hatcher L, Smith FE, Wilson DThe hypotriglyceridemic effect of fish oil in adult-onset diabetes without adverse glucose controlAnn N Y Acad Sci.(1993 Jun 14)
- Blood glucose - M Gorety Jacobo-Cejudo, Roxana Valdés-Ramos, Ana L Guadarrama-López, Rosa-Virgen Pardo-Morales, Beatriz E Martínez-Carrillo, Laurence S HarbigeEffect of n-3 Polyunsaturated Fatty Acid Supplementation on Metabolic and Inflammatory Biomarkers in Type 2 Diabetes Mellitus PatientsNutrients.(2017 Jun 3)
- Blood glucose - L Axelrod, J Camuso, E Williams, K Kleinman, E Briones, D SchoenfeldEffects of a Small Quantity of omega-3 Fatty Acids on Cardiovascular Risk Factors in NIDDM. A Randomized, Prospective, Double-Blind, Controlled StudyDiabetes Care.(1994 Jan)
- Insulin - Annuzzi G, Rivellese A, Capaldo B, Di Marino L, Iovine C, Marotta G, Riccardi GA controlled study on the effects of n-3 fatty acids on lipid and glucose metabolism in non-insulin-dependent diabetic patientsAtherosclerosis.(1991 Mar)
- Apolipoprotein A - Maki KC, Lawless AL, Kelley KM, Dicklin MR, Kaden VN, Schild AL, Rains TM, Marshall JWEffects of prescription omega-3-acid ethyl esters on fasting lipid profile in subjects with primary hypercholesterolemiaJ Cardiovasc Pharmacol.(2011 Apr)
- Weight - Alison M Hill, Jonathan D Buckley, Karen J Murphy, and Peter RC HoweCombining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factorsThe American Journal of Clinical Nutrition.()
- High-density lipoprotein (HDL) - Eslick GD, Howe PR, Smith C, Priest R, Bensoussan ABenefits of fish oil supplementation in hyperlipidemia: a systematic review and meta-analysisInt J Cardiol.(2008 Sep 9)
- High-density lipoprotein (HDL) - Warner JG Jr, Ullrich IH, Albrink MJ, Yeater RACombined effects of aerobic exercise and omega-3 fatty acids in hyperlipidemic personsMed Sci Sports Exerc.(1989 Oct)
- High-density lipoprotein (HDL) - Davidson MH, Stein EA, Bays HE, Maki KC, Doyle RT, Shalwitz RA, Ballantyne CM, Ginsberg HN, COMBination of prescription Omega-3 with Simvastatin (COMBOS) InvestigatorsEfficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled studyClin Ther.(2007 Jul)
- High-density lipoprotein (HDL) - Maki KC, McKenney JM, Reeves MS, Lubin BC, Dicklin MREffects of adding prescription omega-3 acid ethyl esters to simvastatin (20 mg/day) on lipids and lipoprotein particles in men and women with mixed dyslipidemiaAm J Cardiol.(2008 Aug 15)
- Triglycerides - Hanwell HE, Kay CD, Lampe JW, Holub BJ, Duncan AMAcute fish oil and soy isoflavone supplementation increase postprandial serum (n-3) polyunsaturated fatty acids and isoflavones but do not affect triacylglycerols or biomarkers of oxidative stress in overweight and obese hypertriglyceridemic menJ Nutr.(2009 Jun)
- Triglycerides - Oelrich B, Dewell A, Gardner CDEffect of fish oil supplementation on serum triglycerides, LDL cholesterol and LDL subfractions in hypertriglyceridemic adultsNutr Metab Cardiovasc Dis.(2011 Sep 15)
- Platelet Aggregation - Serebruany VL, Miller M, Pokov AN, Lynch D, Jensen JK, Hallén J, Atar DEarly impact of prescription Omega-3 fatty acids on platelet biomarkers in patients with coronary artery disease and hypertriglyceridemiaCardiology.(2011)
- Blood glucose - Babak Roshanravan, Saeed Samarghandian, Milad Ashrafizadeh, Alireza Amirabadizadeh, Farhad Saeedi, Tahereh FarkhondehMetabolic Impact of Saffron and Crocin: An Updated Systematic and Meta-Analysis of Randomised Clinical TrialsArch Physiol Biochem.(2020 Feb 4)
- Blood glucose - Fatemeh Ebrahimi, Amirhossein Sahebkar, Naheed Aryaeian, Naseh Pahlavani, Soudabeh Fallah, Nariman Moradi, Davoud Abbasi, Agha Fatemeh HosseiniEffects Of Saffron Supplementation On Inflammation And Metabolic Responses In Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled TrialDiabetes Metab Syndr Obes.(2019 Oct 14)
- Blood glucose - Milajerdi A, Jazayeri S, Hashemzadeh N, Shirzadi E, Derakhshan Z, Djazayeri A, Akhondzadeh SThe effect of saffron (Crocus sativus L.) hydroalcoholic extract on metabolic control in type 2 diabetes mellitus: A triple-blinded randomized clinical trialJ Res Med Sci.(2018 Feb 20)
- High-density lipoprotein (HDL) - Ali Sahraian, Sina Jelodar, Zahra Javid, Arash Mowla, Laaya AhmadzadehStudy the effects of saffron on depression and lipid profiles: A double blind comparative studyAsian J Psychiatr.(2016 Aug)
- Intraocular Pressure - Fernando Cardona, Francisco J Tinahones, Eduardo Collantes, Eduardo Garcia-Fuentes, Alejandro Escudero, Federico SoriguerResponse to a urate-lowering diet according to polymorphisms in the apolipoprotein AI-CIII-AIV clusterJ Rheumatol.(2005 May)
- Blood glucose - Siervo M, Lara J, Chowdhury S, Ashor A, Oggioni C, Mathers JCEffects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysisBr J Nutr.(2015 Jan 14)
- Blood glucose - Lari A, Sohouli MH, Fatahi S, Cerqueira HS, Santos HO, Pourrajab B, Rezaei M, Saneie S, Rahideh STThe effects of the Dietary Approaches to Stop Hypertension (DASH) diet on metabolic risk factors in patients with chronic disease: A systematic review and meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis.(2021 Sep 22)
- Blood glucose - Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh AThe effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized controlled clinical trialClin Nutr ESPEN.(2019 Oct)
- High-density lipoprotein (HDL) - Oanetta, C. Jonk, Y, Shapiro, AProspective randomized clinical trial evaluating the impact of vinegar on lipids in non-diabeticsWorld J. Cardiovasc. Dis.()
- Blood glucose - B Andallu, B RadhikaHypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) rootIndian J Exp Biol.(2000 Jun)
- Blood glucose - Fabio Galvano, Giovanni Li Volti, Michele Malaguarnera, Teresio Avitabile, Tijana Antic, Marco Vacante, Mariano MalaguarneraEffects of simvastatin and carnitine versus simvastatin on lipoprotein(a) and apoprotein(a) in type 2 diabetes mellitusExpert Opin Pharmacother.(2009 Aug)
- Blood glucose - Aneliya Parvanova, Matias Trillini, Manuel A Podestà, Ilian P Iliev, Carolina Aparicio, Annalisa Perna, Francesco Peraro, Nadia Rubis, Flavio Gaspari, Antonio Cannata, Silvia Ferrari, Antonio C Bossi, Roberto Trevisan, Sreejith Parameswaran, Jonathan S Chávez-Iñiguez, Fahrudin Masnic, Sidy Mohamed Seck, Teerayuth Jiamjariyaporn, Monica Cortinovis, Luca Perico, Kanishka Sharma, Giuseppe Remuzzi, Piero Ruggenenti, David G WarnockBlood Pressure and Metabolic Effects of Acetyl-l-Carnitine in Type 2 Diabetes: DIABASI Randomized Controlled TrialJ Endocr Soc.(2018 Mar 22)
- Blood glucose - Giuseppe Derosa, Arrigo F G Cicero, Antonio Gaddi, Amedeo Mugellini, Leonardina Ciccarelli, Roberto FogariThe effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitusClin Ther.(2003 May)
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- High-density lipoprotein (HDL) - Bloomer RJ, Tschume LC, Smith WAGlycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjectsInt J Vitam Nutr Res.(2009 May)
- High-density lipoprotein (HDL) - Francesco Brescia, Elisabetta Balestra, Maria Grazia Iasella, Aurelia Bellomo DamatoEffects of combined treatment with simvastatin and L-carnitine on triglyceride levels in diabetic patients with hyperlipidaemiaClin Drug Investig.(2002 Nov)
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- Glycemic Control - Malaguarnera M, Gargante MP, Russo C, Antic T, Vacante M, Malaguarnera M, Avitabile T, Li Volti G, Galvano FL-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trialAm J Gastroenterol.(2010 Jun)
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- Blood glucose - Anderson RA, Cheng N, Bryden NA, Polansky MM, Cheng N, Chi J, Feng JElevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetesDiabetes.(1997 Nov)
- Blood glucose - Ghosh D, Bhattacharya B, Mukherjee B, Manna B, Sinha M, Chowdhury J, Chowdhury SRole of chromium supplementation in Indians with type 2 diabetes mellitusJ Nutr Biochem.(2002 Nov)
- Blood glucose - Racek J, Trefil L, Rajdl D, Mudrová V, Hunter D, Senft VInfluence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitusBiol Trace Elem Res.(2006 Mar)
- Blood glucose - Bahijiri SM, Mira SA, Mufti AM, Ajabnoor MAThe effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetesSaudi Med J.(2000 Sep)
- Weight - Rhee YS, Hermann JR, Burnham K, Arquitt AB, Stoecker BJThe effects of chromium and copper supplementation on mitogen-stimulated T cell proliferation in hypercholesterolaemic postmenopausal womenClin Exp Immunol.(2002 Mar)
- Total cholesterol - Preuss HG, Wallerstedt D, Talpur N, Tutuncuoglu SO, Echard B, Myers A, Bui M, Bagchi DEffects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot studyJ Med.(2000)
- Blood glucose - Klein GA, Stefanuto A, Boaventura BC, de Morais EC, Cavalcante Lda S, de Andrade F, Wazlawik E, Di Pietro PF, Maraschin M, da Silva ELMate tea (Ilex paraguariensis) improves glycemic and lipid profiles of type 2 diabetes and pre-diabetes individuals: a pilot studyJ Am Coll Nutr.(2011 Oct)
- Low-density lipoprotein (LDL) - Brunna Cristina Bremer Boaventura, Patrícia Faria Di Pietro, Aliny Stefanuto, Graziela Alessandra Klein, Elayne Cristina de Morais, Fernanda de Andrade, Elisabeth Wazlawik, Edson Luiz da SilvaAssociation of mate tea (Ilex paraguariensis) intake and dietary intervention and effects on oxidative stress biomarkers of dyslipidemic subjectsNutrition.(2012 Jun)
- Blood glucose - Arpita Basu, Mei Du, Misti J Leyva, Karah Sanchez, Nancy M Betts, Mingyuan Wu, Christopher E Aston, Timothy J LyonsBlueberries decrease cardiovascular risk factors in obese men and women with metabolic syndromeJ Nutr.(2010 Sep)
- Blood glucose - Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, Asgary S, Ghannadi AClinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trialMed Arh.(2012)
- Blood glucose - Lin Guan, Peng MiaoThe effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trialsEur J Pharmacol.(2020 Oct 15)
- Blood glucose - Huseini HF, Darvishzadeh F, Heshmat R, Jafariazar Z, Raza M, Larijani BThe clinical investigation of Citrullus colocynthis (L.) schrad fruit in treatment of Type II diabetic patients: a randomized, double blind, placebo-controlled clinical trialPhytother Res.(2009 Aug)
- Blood glucose - Zhang P, Yang C, Guo H, Wang J, Lin S, Li H, Yang Y, Ling WTreatment of coenzyme Q10 for 24 weeks improves lipid and glycemic profile in dyslipidemic individualsJ Clin Lipidol.(2018 Mar - Apr)
- High-density lipoprotein (HDL) - Mohseni M, Vafa M, Zarrati M, Shidfar F, Hajimiresmail SJ, Rahimi Forushani ABeneficial Effects of Coenzyme Q10 Supplementation on Lipid Profile and Intereukin-6 and Intercellular Adhesion Molecule-1 Reduction, Preliminary Results of a Double-blind Trial in Acute Myocardial InfarctionInt J Prev Med.(2015 Aug 7)
- Blood glucose - Muhammad S Mansour, Yu-Ming Ni, Amy L Roberts, Michael Kelleman, Arindam Roychoudhury, Marie-Pierre St-OngeGinger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot studyMetabolism.(2012 Oct)
- High-density lipoprotein (HDL) - Alizadeh-Navaei R, Roozbeh F, Saravi M, Pouramir M, Jalali F, Moghadamnia AAInvestigation of the effect of ginger on the lipid levels. A double blind controlled clinical trialSaudi Med J.(2008 Sep)
- Blood glucose - Yoshida H, Yanai H, Ito K, Tomono Y, Koikeda T, Tsukahara H, Tada NAdministration of natural astaxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemiaAtherosclerosis.(2010 Apr)
- Blood glucose - Koziróg M, Poliwczak AR, Duchnowicz P, Koter-Michalak M, Sikora J, Broncel MMelatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndromeJ Pineal Res.(2011 Apr)
- Blood glucose - Alireza Ostadrahimi, Akbar Taghizadeh, Majid Mobasseri, Nazila Farrin, Laleh Payahoo, Zahra Beyramalipoor Gheshlaghi, Morteza VahedjabbariEffect of probiotic fermented milk (kefir) on glycemic control and lipid profile in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trialIran J Public Health.(2015 Feb)
- High-density lipoprotein (HDL) - Marie-Pierre St-Onge, Edward R Farnworth, Tony Savard, Denise Chabot, Akier Mafu, Peter J H JonesKefir consumption does not alter plasma lipid levels or cholesterol fractional synthesis rates relative to milk in hyperlipidemic men: a randomized controlled trial [ISRCTN10820810]BMC Complement Altern Med.(2002)
- Blood glucose - Sierra M, García JJ, Fernández N, Diez MJ, Calle APTherapeutic effects of psyllium in type 2 diabetic patientsEur J Clin Nutr.(2002 Sep)
- Blood glucose - Rodríguez-Morán M, Guerrero-Romero F, Lazcano-Burciaga GLipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetesJ Diabetes Complications.(1998 Sep-Oct)
- High-density lipoprotein (HDL) - Wei ZH, Wang H, Chen XY, Wang BS, Rong ZX, Wang BS, Su BH, Chen HZTime- and dose-dependent effect of psyllium on serum lipids in mild-to-moderate hypercholesterolemia: a meta-analysis of controlled clinical trials.Eur J Clin Nutr.(2009 Jul)
- Total cholesterol - Dennison BA, Levine DMRandomized, double-blind, placebo-controlled, two-period crossover clinical trial of psyllium fiber in children with hypercholesterolemiaJ Pediatr.(1993 Jul)
- Low-density lipoprotein (LDL) - Malin Schoeneck, David IggmanThe effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trialsNutr Metab Cardiovasc Dis.(2021 May 6)
- Blood glucose - Kim JH, Jung WS, Choi NJ, Kim DO, Shin DH, Kim YJHealth-promoting effects of bovine colostrum in Type 2 diabetic patients can reduce blood glucose, cholesterol, triglyceride and ketonesJ Nutr Biochem.(2009 Apr)
- Blood glucose - Andersson U, Berger K, Högberg A, Landin-Olsson M, Holm CEffects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese personsEur J Clin Nutr.(2012 May)
- Blood glucose - Maeba R, Hara H, Ishikawa H, Hayashi S, Yoshimura N, Kusano J, Takeoka Y, Yasuda D, Okazaki T, Kinoshita M, Teramoto TMyo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndromeJ Nutr Sci Vitaminol (Tokyo).(2008 Jun)
- Blood glucose - Englisch W, Beckers C, Unkauf M, Ruepp M, Zinserling VEfficacy of Artichoke dry extract in patients with hyperlipoproteinemiaArzneimittelforschung.(2000 Mar)
- High-density lipoprotein (HDL) - Bundy R, Walker AF, Middleton RW, Wallis C, Simpson HCArtichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trialPhytomedicine.(2008 Sep)
- Total cholesterol - Lupattelli G, Marchesi S, Lombardini R, Roscini AR, Trinca F, Gemelli F, Vaudo G, Mannarino EArtichoke juice improves endothelial function in hyperlipemiaLife Sci.(2004 Dec 31)
- Blood glucose - Castilla P, Echarri R, Dávalos A, Cerrato F, Ortega H, Teruel JL, Lucas MF, Gómez-Coronado D, Ortuño J, Lasunción MAConcentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjectsAm J Clin Nutr.(2006 Jul)
- Blood glucose - Woodman RJ, Mori TA, Burke V, Puddey IB, Watts GF, Beilin LJEffects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertensionAm J Clin Nutr.(2002 Nov)
- High-density lipoprotein (HDL) - Wei MY, Jacobson TAEffects of eicosapentaenoic acid versus docosahexaenoic acid on serum lipids: a systematic review and meta-analysisCurr Atheroscler Rep.(2011 Oct 6)
- Blood glucose - Kuriyan R, Kumar DR, R R, Kurpad AVAn evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trialBMC Complement Altern Med.(2010 Jun 17)
- Apolipoprotein A - Mozaffari-Khosravi H, Jalali-Khanabadi BA, Afkhami-Ardekani M, Fatehi FEffects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetesJ Altern Complement Med.(2009 Aug)
- Weight - Hernández-Pérez F, Herrera-Arellano ATherapeutic use Hibiscus sabadariffa extract in the treatment of hypercholesterolemia. A randomized clinical trialRev Med Inst Mex Seguro Soc.(2011 Sep-Oct)
- Blood glucose - Khorasanian AS, Fateh ST, Gholami F, Rasaei N, Gerami H, Khayyatzadeh SS, Shiraseb F, Asbaghi OThe effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose-response meta-analysis.Front Nutr.(2023)
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- High-density lipoprotein (HDL) - Miwa Y, Yamada M, Sunayama T, Mitsuzumi H, Tsuzaki Y, Chaen H, Mishima Y, Kibata MEffects of glucosyl hesperidin on serum lipids in hyperlipidemic subjects: preferential reduction in elevated serum triglyceride levelJ Nutr Sci Vitaminol (Tokyo).(2004 Jun)
- High-density lipoprotein (HDL) - Miwa Y, Mitsuzumi H, Sunayama T, Yamada M, Okada K, Kubota M, Chaen H, Mishima Y, Kibata MGlucosyl hesperidin lowers serum triglyceride level in hypertriglyceridemic subjects through the improvement of very low-density lipoprotein metabolic abnormalityJ Nutr Sci Vitaminol (Tokyo).(2005 Dec)
- Blood glucose - Kastorini, C.M., et al.The effect of Mediterranean diet on metabolic syndrome and its components: a meta-analysis of 50 studies and 534,906 individualsJ Am Coll Cardiol.(2011-03-08)
- Endothelial Function - Shannon OM, Mendes I, Köchl C, Mazidi M, Ashor AW, Rubele S, Minihane AM, Mathers JC, Siervo MMediterranean Diet Increases Endothelial Function in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.J Nutr.(2020-May-01)
- Blood glucose - Zamani M, Ashtary-Larky D, Nosratabadi S, Bagheri R, Wong A, Rafiei MM, Asiabar MM, Khalili P, Asbaghi O, Davoodi SHThe effects of Gymnema Sylvestre supplementation on lipid profile, glycemic control, blood pressure, and anthropometric indices in adults: A systematic review and meta-analysis.Phytother Res.(2023-Mar)
- Blood glucose - Sabet HR, Ahmadi M, Akrami M, Motamed M, Keshavarzian O, Abdollahi M, Rezaei M, Akbari HEffects of flaxseed supplementation on weight loss, lipid profiles, glucose, and high-sensitivity C-reactive protein in patients with coronary artery disease: A systematic review and meta-analysis of randomized controlled trials.Clin Cardiol.(2024-Jan)
- High-density lipoprotein (HDL) - Pan A, Yu D, Demark-Wahnefried W, Franco OH, Lin XMeta-analysis of the effects of flaxseed interventions on blood lipidsAm J Clin Nutr.(2009 Aug)
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- High-density lipoprotein (HDL) - Sadat Masjedi M, Mohammadi Pour P, Shokoohinia Y, Asgary SEffects of Flaxseed on Blood Lipids in Healthy and Dyslipidemic Subjects: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Curr Probl Cardiol.(2022 Jul)
- Blood glucose - Ding KX, Gao TL, Xu R, Cai J, Zhang HQ, Sun YY, Zhong F, Ma AGQuantifying the Effect of Supplementation with Algae and Its Extracts on Glycolipid Metabolism: A Meta-Analysis of Randomized Controlled Trials.Nutrients.(2020-Jun-08)
- Blood glucose - Fallah AA, Sarmast E, Habibian Dehkordi S, Engardeh J, Mahmoodnia L, Khaledifar A, Jafari TEffect of Chlorella supplementation on cardiovascular risk factors: A meta-analysis of randomized controlled trialsClin Nutr.(2018-Dec)
- High-density lipoprotein (HDL) - Sherafati N, Bideshki MV, Behzadi M, Mobarak S, Asadi M, Sadeghi OEffect of supplementation with Chlorella vulgaris on lipid profile in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.Complement Ther Med.(2022-Jun)
- Blood glucose - Zou Y, Liao D, Huang H, Li T, Chi HA systematic review and meta-analysis of beta-glucan consumption on glycemic control in hypercholesterolemic individuals.Int J Food Sci Nutr.(2015)
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- High-density lipoprotein (HDL) - Kojuri J, Vosoughi AR, Akrami MEffects of anethum graveolens and garlic on lipid profile in hyperlipidemic patientsLipids Health Dis.(2007 Mar 1)
- Blood glucose - Zhou S, Cheng F, He J, Xu T, Zhang X, Wan S, Qi J, He J, Chen F, Luo J, Luo Y, An PEffects of high-quality protein supplementation on cardiovascular risk factors in individuals with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials.Clin Nutr.(2024 Aug)
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- Apolipoprotein A - Chedraui P, San Miguel G, Hidalgo L, Morocho N, Ross SEffect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass indexGynecol Endocrinol.(2008 Nov)
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- Apolipoprotein A - Jones ML, Martoni CJ, Prakash SCholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trialEur J Clin Nutr.(2012 Nov)
- High-density lipoprotein (HDL) - Jones ML, Martoni CJ, Parent M, Prakash SCholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adultsBr J Nutr.(2012 May)
- Plasma Vitamin D - Jones ML, Martoni CJ, Prakash SOral supplementation with probiotic L. reuteri NCIMB 30242 increases mean circulating 25-hydroxyvitamin D: a post hoc analysis of a randomized controlled trialJ Clin Endocrinol Metab.(2013 Jul)
- Apolipoprotein A - Schwab U, Alfthan G, Aro A, Uusitupa MLong-term effect of betaine on risk factors associated with the metabolic syndrome in healthy subjectsEur J Clin Nutr.(2011 Jan)
- Weight - Zittermann A, Frisch S, Berthold HK, Götting C, Kuhn J, Kleesiek K, Stehle P, Koertke H, Koerfer RVitamin D supplementation enhances the beneficial effects of weight loss on cardiovascular disease risk markersAm J Clin Nutr.(2009 May)
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- Weight - Stanko RT, Reynolds HR, Hoyson R, Janosky JE, Wolf RPyruvate supplementation of a low-cholesterol, low-fat diet: effects on plasma lipid concentrations and body composition in hyperlipidemic patientsAm J Clin Nutr.(1994 Feb)
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- Weight - Hana Kahleova, Kitt Falk Petersen, Gerald I Shulman, Jihad Alwarith, Emilie Rembert, Andrea Tura, Martin Hill, Richard Holubkov, Neal D BarnardEffect of a Low-Fat Vegan Diet on Body Weight, Insulin Sensitivity, Postprandial Metabolism, and Intramyocellular and Hepatocellular Lipid Levels in Overweight Adults: A Randomized Clinical TrialJAMA Netw Open.(2020 Nov 2)
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- High-density lipoprotein (HDL) - Minggang Wei, Peihua Xiong, Ling Zhang, Mei Fei, Aiping Chen, Fengling LiPerilla oil and exercise decrease expressions of tumor necrosis factor-alpha, plasminogen activator inhibitor-1 and highly sensitive C-reactive protein in patients with hyperlipidemiaJ Tradit Chin Med.(2013 Apr)
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- High-density lipoprotein (HDL) - Sharpe SJ, Gamble GD, Sharpe DNCholesterol-lowering and blood pressure effects of immune milkAm J Clin Nutr.(1994 Apr)
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