General Cardiovascular Health

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    Last Updated: October 13, 2024

    Cardiovascular health refers to the overall ability of the heart and blood vessels to distribute blood, nutrients, and gasses throughout the body.

    General Cardiovascular Health falls under the Cardiovascular Health category.

    Examine Database: General Cardiovascular Health

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    Examine Database References

    1. Triglycerides - Bernstein AM, Ding EL, Willett WC, Rimm EBA meta-analysis shows that docosahexaenoic acid from algal oil reduces serum triglycerides and increases HDL-cholesterol and LDL-cholesterol in persons without coronary heart diseaseJ Nutr.(2012 Jan)
    2. Triglycerides - Ciubotaru I, Lee YS, Wander RCDietary fish oil decreases C-reactive protein, interleukin-6, and triacylglycerol to HDL-cholesterol ratio in postmenopausal women on HRTJ Nutr Biochem.(2003 Sep)
    3. Triglycerides - Boberg M, Pollare T, Siegbahn A, Vessby BSupplementation with n-3 fatty acids reduces triglycerides but increases PAI-1 in non-insulin-dependent diabetes mellitusEur J Clin Invest.(1992 Oct)
    4. Triglycerides - Dangardt F, Osika W, Chen Y, Nilsson U, Gan LM, Gronowitz E, Strandvik B, Friberg POmega-3 fatty acid supplementation improves vascular function and reduces inflammation in obese adolescentsAtherosclerosis.(2010 Oct)
    5. High-density lipoprotein (HDL) - Alison M Hill, Jonathan D Buckley, Karen J Murphy, and Peter RC HoweCombining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factorsThe American Journal of Clinical Nutrition.()
    6. Cell Adhesion Factors - Maria C Paulo, Ana M Andrade, Maria L Andrade, Maria G Morais, Mairead Kiely, Dolores Parra, J Alfredo Martinéz, Inga Thorsdottir, Narcisa M BandarraInfluence of n-3 polyunsaturated fatty acids on soluble cellular adhesion molecules as biomarkers of cardiovascular risk in young healthy subjectsNutr Metab Cardiovasc Dis.(2008 Dec)
    7. Cell Adhesion Factors - Kooshki A, Taleban FA, Tabibi H, Hedayati MEffects of marine omega-3 fatty acids on serum systemic and vascular inflammation markers and oxidative stress in hemodialysis patientsAnn Nutr Metab.(2011)
    8. Cell Adhesion Factors - Miles EA, Thies F, Wallace FA, Powell JR, Hurst TL, Newsholme EA, Calder PCInfluence of age and dietary fish oil on plasma soluble adhesion molecule concentrationsClin Sci (Lond).(2001 Jan)
    9. Pre-Eclampsia Risk - Zhou SJ, Yelland L, McPhee AJ, Quinlivan J, Gibson RA, Makrides MFish-oil supplementation in pregnancy does not reduce the risk of gestational diabetes or preeclampsiaAm J Clin Nutr.(2012 Jun)
    10. Insulin - G Fontani, F Corradeschi, A Felici, F Alfatti, R Bugarini, A I Fiaschi, D Cerretani, G Montorfano, A M Rizzo, B BerraBlood profiles, body fat and mood state in healthy subjects on different diets supplemented with Omega-3 polyunsaturated fatty acidsEur J Clin Invest.(2005 Aug)
    11. Endothelial Function - Pase MP, Grima NA, Sarris JDo long-chain n-3 fatty acids reduce arterial stiffness? A meta-analysis of randomised controlled trialsBr J Nutr.(2011 Oct)
    12. Endothelial Function - Sanders TA, Hall WL, Maniou Z, Lewis F, Seed PT, Chowienczyk PJEffect of low doses of long-chain n-3 PUFAs on endothelial function and arterial stiffness: a randomized controlled trialAm J Clin Nutr.(2011 Oct)
    13. Triglycerides - Karppi J, Rissanen TH, Nyyssönen K, Kaikkonen J, Olsson AG, Voutilainen S, Salonen JTEffects of astaxanthin supplementation on lipid peroxidationInt J Vitam Nutr Res.(2007 Jan)
    14. Triglycerides - Coombes JS, Sharman JE, Fassett RGAstaxanthin has no effect on arterial stiffness, oxidative stress, or inflammation in renal transplant recipients: a randomized controlled trial (the XANTHIN trial)Am J Clin Nutr.(2016 Jan)
    15. Blood Flow - Miyawaki H, Takahashi J, Tsukahara H, Takehara IEffects of astaxanthin on human blood rheologyJ Clin Biochem Nutr.(2008 Sep)
    16. Triglycerides - Yoko Yokoyama, Susan M Levin, Neal D BarnardAssociation between plant-based diets and plasma lipids: a systematic review and meta-analysisNutr Rev.(2017 Sep 1)
    17. Blood Pressure - Persio D Lopez, Eder H Cativo, Steven A Atlas, Clive RosendorffThe Effect of Vegan Diets on Blood Pressure in Adults: A Meta-Analysis of Randomized Controlled TrialsAm J Med.(2019 Jul)
    18. Blood Pressure - Amir Abbasnezhad, Ebrahim Falahi, Michael J Gonzalez, Parivash Kavehi, Faezeh Fouladvand, Razieh ChoghakhoriEffect of Different Dietary Approaches Compared With a Regular Diet on Systolic and Diastolic Blood Pressure in Patients With Type 2 Diabetes: A Systematic Review and Meta-AnalysisDiabetes Res Clin Pract.(2020 May)
    19. Blood Pressure - Joshua Gibbs, Eleanor Gaskin, Chen Ji, Michelle A Miller, Francesco P CappuccioThe effect of plant-based dietary patterns on blood pressure: a systematic review and meta-analysis of controlled intervention trialsJ Hypertens.(2021 Jan)
    20. Triglycerides - Johansson AK, Korte H, Yang B, Stanley JC, Kallio HPSea buckthorn berry oil inhibits platelet aggregationJ Nutr Biochem.(2000 Oct)
    21. Triglycerides - Marianne Raff, Tine Tholstrup, Samar Basu, Pernille Nonboe, Martin Tang Sørensen, Ellen Marie StraarupA diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young menJ Nutr.(2008 Mar)
    22. Triglycerides - Venkatramanan S, Joseph SV, Chouinard PY, Jacques H, Farnworth ER, Jones PJMilk enriched with conjugated linoleic acid fails to alter blood lipids or body composition in moderately overweight, borderline hyperlipidemic individualsJ Am Coll Nutr.(2010 Apr)
    23. High-density lipoprotein (HDL) - Sluijs I, Plantinga Y, de Roos B, Mennen LI, Bots MLDietary supplementation with cis-9,trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adultsAm J Clin Nutr.(2010 Jan)
    24. High-density lipoprotein (HDL) - Lambert EV, Goedecke JH, Bluett K, Heggie K, Claassen A, Rae DE, West S, Dugas J, Dugas L, Meltzeri S, Charlton K, Mohede IConjugated linoleic acid versus high-oleic acid sunflower oil: effects on energy metabolism, glucose tolerance, blood lipids, appetite and body composition in regularly exercising individualsBr J Nutr.(2007 May)
    25. Blood Pressure - Raff M, Tholstrup T, Sejrsen K, Straarup EM, Wiinberg NDiets rich in conjugated linoleic acid and vaccenic acid have no effect on blood pressure and isobaric arterial elasticity in healthy young menJ Nutr.(2006 Apr)
    26. Blood Pressure - M F Engberink, J M Geleijnse, A J Wanders, I A BrouwerThe effect of conjugated linoleic acid, a natural trans fat from milk and meat, on human blood pressure: results from a randomized crossover feeding studyJ Hum Hypertens.(2012 Feb)
    27. Liver Enzymes - Smedman A, Vessby B, Basu SIsomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitorClin Sci (Lond).(2004 Jan)
    28. Triglycerides - Asmaa S Abdelhamid, Tracey J Brown, Julii S Brainard, Priti Biswas, Gabrielle C Thorpe, Helen J Moore, Katherine Ho Deane, Carolyn D Summerbell, Helen V Worthington, Fujian Song, Lee HooperOmega-3 fatty acids for the primary and secondary prevention of cardiovascular diseaseCochrane Database Syst Rev.(2020 Feb 29)
    29. Triglycerides - Hao Yue, Bin Qiu, Min Jia, Wei Liu, Xiao-Fei Guo, Na Li, Zhi-Xiang Xu, Fang-Ling Du, Tongcheng Xu, Duo LiEffects of α-linolenic acid intake on blood lipid profiles:a systematic review and meta-analysis of randomized controlled trialsCrit Rev Food Sci Nutr.(2021)
    30. Triglycerides - Modaghegh MH, Shahabian M, Esmaeili HA, Rajbai O, Hosseinzadeh HSafety evaluation of saffron (Crocus sativus) tablets in healthy volunteersPhytomedicine.(2008 Dec)
    31. Triglycerides - Mohammad Zamani, Mahtab Zarei, Mahlagha Nikbaf-Shandiz, Fatemeh Gholami, Amir Mehdi Hosseini, Maryam Nadery, Farideh Shiraseb, Omid AsbaghiThe effects of saffron supplementation on cardiovascular risk factors in adults: A systematic review and dose-response meta-analysisFront Nutr.(2022 Dec 8)
    32. Blood Pressure - Paria Azimi, Reza Ghiasvand, Awat Feizi, Javad Hosseinzadeh, Maryam Bahreynian, Mitra Hariri, Hossein Khosravi-BoroujeniEffect of cinnamon, cardamom, saffron and ginger consumption on blood pressure and a marker of endothelial function in patients with type 2 diabetes mellitus: A randomized controlled clinical trialBlood Press.(2016 Jun)
    33. Oxidative Stress Biomarkers - Abedi A, Ghobadi H, Sharghi A, Iranpour S, Fazlzadeh M, Aslani MREffect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials.Front Med (Lausanne).(2023)
    34. Blood Clotting - Hossein Ayatollahi, Atefeh Ordoei Javan, Mohammad Khajedaluee, Masood Shahroodian, Hossein HosseinzadehEffect of Crocus sativus L. (saffron) on coagulation and anticoagulation systems in healthy volunteersPhytother Res.(2014 Apr)
    35. Triglycerides - Marshall MW, Kliman PG, Washington VA, Mackin JF, Weinland BTEffects of biotin on lipids and other constituents of plasma of healthy men and womenArtery.(1980)
    36. Triglycerides - Spangler L, Newton KM, Grothaus LC, Reed SD, Ehrlich K, LaCroix AZThe effects of black cohosh therapies on lipids, fibrinogen, glucose and insulinMaturitas.(2007 Jun 20)
    37. Coronary Artery Disease Risk - Michael Bebenek, Wolfgang Kemmler, Simon von Stengel, Klaus Engelke, Willi A KalenderEffect of exercise and Cimicifuga racemosa (CR BNO 1055) on bone mineral density, 10-year coronary heart disease risk, and menopausal complaints: the randomized controlled Training and Cimicifuga racemosa Erlangen (TRACE) studyMenopause.(2010 Jul)
    38. Triglycerides - E A Johnston, K S Petersen, P M Kris-EthertonDaily intake of non-fried potato does not affect markers of glycaemia and is associated with better diet quality compared with refined grains: a randomised, crossover study in healthy adultsBr J Nutr.(2020 May 14)
    39. Triglycerides - Eunice Mah, Jacqueline A Schulz, Valerie N Kaden, Andrea L Lawless, Jose Rotor, Libertie B Mantilla, DeAnn J LiskaCashew consumption reduces total and LDL cholesterol: a randomized, crossover, controlled-feeding trialAm J Clin Nutr.(2017 May)
    40. Triglycerides - Vigna GB, Costantini F, Aldini G, Carini M, Catapano A, Schena F, Tangerini A, Zanca R, Bombardelli E, Morazzoni P, Mezzetti A, Fellin R, Maffei Facino REffect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokersMetabolism.(2003 Oct)
    41. Blood Pressure - Feringa HH, Laskey DA, Dickson JE, Coleman CIThe effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trialsJ Am Diet Assoc.(2011 Aug)
    42. Blood Flow - Shenoy SF, Keen CL, Kalgaonkar S, Polagruto JAEffects of grape seed extract consumption on platelet function in postmenopausal womenThromb Res.(2007)
    43. Leg Edema - Sano A, Tokutake S, Seo AProanthocyanidin-rich grape seed extract reduces leg swelling in healthy women during prolonged sittingJ Sci Food Agric.(2012 Jul 2)
    44. Triglycerides - Minggang Wei, Peihua Xiong, Ling Zhang, Mei Fei, Aiping Chen, Fengling LiPerilla oil and exercise decrease expressions of tumor necrosis factor-alpha, plasminogen activator inhibitor-1 and highly sensitive C-reactive protein in patients with hyperlipidemiaJ Tradit Chin Med.(2013 Apr)
    45. Triglycerides - Raut AA, Rege NN, Tadvi FM, Solanki PV, Kene KR, Shirolkar SG, Pandey SN, Vaidya RA, Vaidya ABExploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteersJ Ayurveda Integr Med.(2012 Jul)
    46. Blood Pressure - Sandhu JS, Shah B, Shenoy S, Chauhan S, Lavekar GS, Padhi MMEffects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young adultsInt J Ayurveda Res.(2010 Jul)
    47. Triglycerides - Martina V, Benso A, Gigliardi VR, Masha A, Origlia C, Granata R, Ghigo EShort-term dehydroepiandrosterone treatment increases platelet cGMP production in elderly male subjectsClin Endocrinol (Oxf).(2006 Mar)
    48. Blood glucose - Kawano H, Yasue H, Kitagawa A, Hirai N, Yoshida T, Soejima H, Miyamoto S, Nakano M, Ogawa HDehydroepiandrosterone supplementation improves endothelial function and insulin sensitivity in menJ Clin Endocrinol Metab.(2003 Jul)
    49. Triglycerides - Jamal Hallajzadeh, Alireza Milajerdi, Moein Mobini, Elaheh Amirani, Susan Azizi, Elhameh Nikkhah, Babak Bahadori, Razieh Sheikhsoleimani, Seyyed Mehdi MirhashemiEffects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trialsPhytother Res.(2020 Oct)
    50. Triglycerides - Qidwai W, Hamza HB, Qureshi R, Gilani AEffectiveness, safety, and tolerability of powdered Nigella sativa (kalonji) seed in capsules on serum lipid levels, blood sugar, blood pressure, and body weight in adults: results of a randomized, double-blind controlled trialJ Altern Complement Med.(2009 Jun)
    51. Blood Pressure - Kavyani Z, Musazadeh V, Safaei E, Mohammadi Asmaroud M, Khashakichafi F, Ahrabi SS, Dehghan PAntihypertensive effects of Nigella sativa supplementation: An updated systematic review and meta-analysis of randomized controlled trials.Phytother Res.(2023-Aug)
    52. Triglycerides - Sutton EF, Beyl R, Early KS, Cefalu WT, Ravussin E, Peterson CMEarly Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with PrediabetesCell Metab.(2018 Jun 5)
    53. Triglycerides - B D Horne, J B Muhlestein, D L Lappé, H T May, J F Carlquist, O Galenko, K D Brunisholz, J L AndersonRandomized cross-over trial of short-term water-only fasting: metabolic and cardiovascular consequencesNutr Metab Cardiovasc Dis.(2013 Nov)
    54. Triglycerides - Howes JB, Tran D, Brillante D, Howes LGEffects of dietary supplementation with isoflavones from red clover on ambulatory blood pressure and endothelial function in postmenopausal type 2 diabetesDiabetes Obes Metab.(2003 Sep)
    55. Triglycerides - Nestel PJ, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West LIsoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal womenJ Clin Endocrinol Metab.(1999 Mar)
    56. Triglycerides - Blakesmith SJ, Lyons-Wall PM, George C, Joannou GE, Petocz P, Samman SEffects of supplementation with purified red clover (Trifolium pratense) isoflavones on plasma lipids and insulin resistance in healthy premenopausal womenBr J Nutr.(2003 Apr)
    57. Triglycerides - Campbell MJ, Woodside JV, Honour JW, Morton MS, Leathem AJEffect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers: a pilot studyEur J Clin Nutr.(2004 Jan)
    58. Triglycerides - Atkinson C, Oosthuizen W, Scollen S, Loktionov A, Day NE, Bingham SAModest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old womenJ Nutr.(2004 Jul)
    59. Blood Pressure - Teede HJ, McGrath BP, DeSilva L, Cehun M, Fassoulakis A, Nestel PJIsoflavones reduce arterial stiffness: a placebo-controlled study in men and postmenopausal womenArterioscler Thromb Vasc Biol.(2003 Jun 1)
    60. Total cholesterol - Powles TJ, Howell A, Evans DG, McCloskey EV, Ashley S, Greenhalgh R, Affen J, Flook LA, Tidy ARed clover isoflavones are safe and well tolerated in women with a family history of breast cancerMenopause Int.(2008 Mar)
    61. Homocysteine - Samman S, Koh HS, Flood VM, Blakesmith SJ, Petocz P, Lyons-Wall PMRed clover (Trifolium pratense) isoflavones and serum homocysteine in premenopausal women: a pilot studyJ Womens Health (Larchmt).(2009 Nov)
    62. Triglycerides - Patricia Victoria Torres-Durán, Aldo Ferreira-Hermosillo, Arnulfo Ramos-Jiménez, Rosa Patricia Hernández-Torres, Marco Antonio Juárez-OropezaEffect of Spirulina maxima on postprandial lipemia in young runners: a preliminary reportJ Med Food.(2012 Aug)
    63. Triglycerides - José J van den Driessche, Jogchum Plat, Maurice C J M Konings, Ronald P MensinkEffects of spirulina and wakame consumption on intestinal cholesterol absorption and serum lipid concentrations in non-hypercholesterolemic adult men and womenEur J Nutr.(2020 Aug)
    64. Weight - Marco Antonio Hernández-Lepe, José Alberto López-Díaz, Marco Antonio Juárez-Oropeza, Rosa Patricia Hernández-Torres, Abraham Wall-Medrano, Arnulfo Ramos-JiménezEffect of Arthrospira (Spirulina) maxima Supplementation and a Systematic Physical Exercise Program on the Body Composition and Cardiorespiratory Fitness of Overweight or Obese Subjects: A Double-Blind, Randomized, and Crossover Controlled TrialMar Drugs.(2018 Oct 1)
    65. Triglycerides - Olthof MR, van Vliet T, Verhoef P, Zock PL, Katan MBEffect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humansPLoS Med.(2005 May)
    66. Blood Flow - Margreet R Olthof, Michiel L Bots, Martijn B Katan, and Petra VerhoefEffect of Folic Acid and Betaine Supplementation on Flow-Mediated Dilation: A Randomized, Controlled Study in Healthy VolunteersPLoS.()
    67. Homocysteine - Steenge GR, Verhoef P, Katan MBBetaine supplementation lowers plasma homocysteine in healthy men and womenJ Nutr.(2003 May)
    68. Triglycerides - Mohammadi M, Ramezani-Jolfaie N, Lorzadeh E, Khoshbakht Y, Salehi-Abargouei AHesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled clinical trialsPhytother Res.(2019 Mar)
    69. Triglycerides - Khorasanian AS, Fateh ST, Gholami F, Rasaei N, Gerami H, Khayyatzadeh SS, Shiraseb F, Asbaghi OThe effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose-response meta-analysis.Front Nutr.(2023)
    70. Triglycerides - Tatiana Moro, Grant Tinsley, Antonino Bianco, Giuseppe Marcolin, Quirico Francesco Pacelli, Giuseppe Battaglia, Antonio Palma, Paulo Gentil, Marco Neri, Antonio PaoliEffects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained malesJ Transl Med.(2016 Oct 13)
    71. Triglycerides - Budoff MJ, Takasu J, Flores FR, Niihara Y, Lu B, Lau BH, Rosen RT, Amagase HInhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary studyPrev Med.(2004 Nov)
    72. Triglycerides - K Rahman, D BillingtonDietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humansJ Nutr.(2000 Nov)
    73. Triglycerides - Silagy C, Neil AGarlic as a lipid lowering agent--a meta-analysisJ R Coll Physicians Lond.(1994 Jan-Feb)
    74. High-density lipoprotein (HDL) - Breithaupt-Grögler K, Ling M, Boudoulas H, Belz GGProtective effect of chronic garlic intake on elastic properties of aorta in the elderlyCirculation.(1997 Oct 21)
    75. Heart Rate - Morris DM, Beloni RK, Wheeler HEEffects of garlic consumption on physiological variables and performance during exercise in hypoxiaAppl Physiol Nutr Metab.(2013 Apr)
    76. Platelet Aggregation - Steiner M, Lin RSChanges in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extractJ Cardiovasc Pharmacol.(1998 Jun)
    77. Platelet Aggregation - Steiner M, Li WAged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functionsJ Nutr.(2001 Mar)
    78. Platelet Aggregation - Scharbert G, Kalb ML, Duris M, Marschalek C, Kozek-Langenecker SAGarlic at dietary doses does not impair platelet functionAnesth Analg.(2007 Nov)
    79. Blood Viscosity - Galduróz JC, Antunes HK, Santos RFGender- and age-related variations in blood viscosity in normal volunteers: a study of the effects of extract of Allium sativum and Ginkgo bilobaPhytomedicine.(2007 Aug)
    80. Hepatopulmonary Syndrome Treatment - De BK, Dutta D, Pal SK, Gangopadhyay S, Das Baksi S, Pani AThe role of garlic in hepatopulmonary syndrome: a randomized controlled trialCan J Gastroenterol.(2010 Mar)
    81. Triglycerides - Lee YJ, Chung HY, Kwak HK, Yoon SThe effects of A. senticosus supplementation on serum lipid profiles, biomarkers of oxidative stress, and lymphocyte DNA damage in postmenopausal womenBiochem Biophys Res Commun.(2008 Oct 10)
    82. Triglycerides - Devaraj S, Vega-López S, Kaul N, Schönlau F, Rohdewald P, Jialal ISupplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profileLipids.(2002 Oct)
    83. Triglycerides - Hadi A, Pourmasoumi M, Mohammadi H, Javaheri A, Rouhani MHThe impact of pycnogenol supplementation on plasma lipids in humans: A systematic review and meta-analysis of clinical trials.Phytother Res.(2019-Feb)
    84. Weight - Malekahmadi M, Moradi Moghaddam O, Firouzi S, Daryabeygi-Khotbehsara R, Shariful Islam SM, Norouzy A, Soltani SEffects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials.Pharmacol Res.(2019-Dec)
    85. C-Reactive Protein (CRP) - Omid Nikpayam, Mohammad Hossein Rouhani, Makan Pourmasoumi, Neda Roshanravan, Ehsan Ghaedi, Hamed MohammadiThe Effect of Pycnogenol Supplementation on Plasma C-Reactive Protein Concentration: a Systematic Review and Meta-AnalysisClin Nutr Res.(2018 Apr)
    86. Blood Pressure - Federica Fogacci, Giuliano Tocci, Amirhossein Sahebkar, Vivianne Presta, Maciej Banach, Arrigo Francesco Giuseppe CiceroEffect of Pycnogenol on Blood Pressure: Findings From a PRISMA Compliant Systematic Review and Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled, Clinical StudiesAngiology.(2020 Mar)
    87. Blood Flow - Nishioka K, Hidaka T, Nakamura S, Umemura T, Jitsuiki D, Soga J, Goto C, Chayama K, Yoshizumi M, Higashi YPycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humansHypertens Res.(2007 Sep)
    88. Triglycerides - Akazawa N, Choi Y, Miyaki A, Tanabe Y, Sugawara J, Ajisaka R, Maeda SCurcumin ingestion and exercise training improve vascular endothelial function in postmenopausal womenNutr Res.(2012 Oct)
    89. Triglycerides - Usharani P, Mateen AA, Naidu MU, Raju YS, Chandra NEffect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week studyDrugs R D.(2008)
    90. High-density lipoprotein (HDL) - Baum L, Cheung SK, Mok VC, Lam LC, Leung VP, Hui E, Ng CC, Chow M, Ho PC, Lam S, Woo J, Chiu HF, Goggins W, Zee B, Wong A, Mok H, Cheng WK, Fong C, Lee JS, Chan MH, Szeto SS, Lui VW, Tsoh J, Kwok TC, Chan IH, Lam CWCurcumin effects on blood lipid profile in a 6-month human studyPharmacol Res.(2007 Dec)
    91. Blood Pressure - Barber-Chamoux N, Milenkovic D, Verny MA, Habauzit V, Pereira B, Lambert C, Richard D, Boby C, Mazur A, Lusson JR, Dubray C, Morand CSubstantial Variability Across Individuals in the Vascular and Nutrigenomic Response to an Acute Intake of Curcumin: A Randomized Controlled TrialMol Nutr Food Res.(2018 Mar)
    92. Blood Pressure - Santos-Parker JR, Strahler TR, Bassett CJ, Bispham NZ, Chonchol MB, Seals DRCurcumin supplementation improves vascular endothelial function in healthy middle-aged and older adults by increasing nitric oxide bioavailability and reducing oxidative stressAging (Albany NY).(2017 Jan 3)
    93. Blood Pressure - Sugawara J, Akazawa N, Miyaki A, Choi Y, Tanabe Y, Imai T, Maeda SEffect of endurance exercise training and curcumin intake on central arterial hemodynamics in postmenopausal women: pilot studyAm J Hypertens.(2012 Jun)
    94. Blood Flow - Oliver JM, Stoner L, Rowlands DS, Caldwell AR, Sanders E, Kreutzer A, Mitchell JB, Purpura M, Jäger RNovel Form of Curcumin Improves Endothelial Function in Young, Healthy Individuals: A Double-Blind Placebo Controlled StudyJ Nutr Metab.(2016)
    95. Triglycerides - Engler MB, Engler MM, Chen CY, Malloy MJ, Browne A, Chiu EY, Kwak HK, Milbury P, Paul SM, Blumberg J, Mietus-Snyder MLFlavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adultsJ Am Coll Nutr.(2004 Jun)
    96. Triglycerides - Shiina Y, Funabashi N, Lee K, Murayama T, Nakamura K, Wakatsuki Y, Daimon M, Komuro IAcute effect of oral flavonoid-rich dark chocolate intake on coronary circulation, as compared with non-flavonoid white chocolate, by transthoracic Doppler echocardiography in healthy adultsInt J Cardiol.(2009 Jan 24)
    97. Triglycerides - Grassi D, Lippi C, Necozione S, Desideri G, Ferri CShort-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy personsAm J Clin Nutr.(2005 Mar)
    98. Triglycerides - Muniyappa R, Hall G, Kolodziej TL, Karne RJ, Crandon SK, Quon MJCocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertensionAm J Clin Nutr.(2008 Dec)
    99. Triglycerides - Crews WD Jr, Harrison DW, Wright JWA double-blind, placebo-controlled, randomized trial of the effects of dark chocolate and cocoa on variables associated with neuropsychological functioning and cardiovascular health: clinical findings from a sample of healthy, cognitively intact older adultsAm J Clin Nutr.(2008 Apr)
    100. Triglycerides - West SG, McIntyre MD, Piotrowski MJ, Poupin N, Miller DL, Preston AG, Wagner P, Groves LF, Skulas-Ray ACEffects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adultsBr J Nutr.(2014 Feb)
    101. High-density lipoprotein (HDL) - Hamed MS, Gambert S, Bliden KP, Bailon O, Singla A, Antonino MJ, Hamed F, Tantry US, Gurbel PADark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot studySouth Med J.(2008 Dec)
    102. Weight - Mogollon JA, Bujold E, Lemieux S, Bourdages M, Blanchet C, Bazinet L, Couillard C, Noël M, Dodin SBlood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trialNutr J.(2013 Apr 8)
    103. Blood Pressure - Almoosawi S, Fyfe L, Ho C, Al-Dujaili EThe effect of polyphenol-rich dark chocolate on fasting capillary whole blood glucose, total cholesterol, blood pressure and glucocorticoids in healthy overweight and obese subjectsBr J Nutr.(2010 Mar)
    104. Blood Pressure - Verawati Sudarma, Sri Sukmaniah, Parlindungan SiregarEffect of dark chocolate on nitric oxide serum levels and blood pressure in prehypertension subjectsActa Med Indones.(2011 Oct)
    105. Blood Pressure - d'El-Rei J, Cunha AR, Burlá A, Burlá M, Oigman W, Neves MF, Virdis A, Medeiros FCharacterisation of hypertensive patients with improved endothelial function after dark chocolate consumptionInt J Hypertens.(2013)
    106. Blood Pressure - Monahan KD, Feehan RP, Kunselman AR, Preston AG, Miller DL, Lott MEDose-dependent increases in flow-mediated dilation following acute cocoa ingestion in healthy older adultsJ Appl Physiol.(2011 Dec)
    107. Adrenaline - Wirtz PH, von Känel R, Meister RE, Arpagaus A, Treichler S, Kuebler U, Huber S, Ehlert UDark chocolate intake buffers stress reactivity in humansJ Am Coll Cardiol.(2014 Jun 3)
    108. Oxidative Stress Biomarkers - Charalambos Vlachopoulos, Konstantinos Aznaouridis, Nikolaos Alexopoulos, Emmanuel Economou, Ioanna Andreadou, Christodoulos StefanadisEffect of dark chocolate on arterial function in healthy individualsAm J Hypertens.(2005 Jun)
    109. Oxidative Stress Biomarkers - Carnevale R, Loffredo L, Pignatelli P, Nocella C, Bartimoccia S, Di Santo S, Martino F, Catasca E, Perri L, Violi FDark chocolate inhibits platelet isoprostanes via NOX2 down-regulation in smokersJ Thromb Haemost.(2012 Jan)
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