High-density lipoprotein (HDL)

    Last Updated: October 17, 2024

    High-density lipoprotein (HDL) is a particle that carries cholesterol from your blood to your liver. Low levels of HDL cholesterol (HDL-C) are associated with a higher risk of cardiovascular disease (CVD), which is why HDL-C is often called the “good cholesterol” (as opposed to LDL-C) — but the reality is more complex.

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    294,129 participants in 620 trials

    HDL-C and heart disease

    High-density lipoproteins (HDL) are particles that carry cholesterol in the blood stream. Low levels of HDL cholesterol (HDL-C; a marker of HDL levels) in the blood has long been recognized as a risk factor for cardiovascular disease (CVD).[1] As a result, HDL is commonly known as "good cholesterol". However, it's increasingly clear that HDL-C is not inherently good or bad.

    Studies testing whether higher HDL lowers the risk heart disease have, by and large, failed to find a benefit. Whether HDL is raised by medication (e.g., CEPT inhibitors, high-dose niacin)[2] or genetic differences,[3] the results are similar — no apparent effect on CVD risk.

    One explanation for this apparent paradox is that HDL has no role in heart disease and low HDL is merely a marker of disease and unhealthy habits. This is certainly possible, since HDL is lowered by insulin resistance (the cause of type 2 diabetes)[4] and physical inactivity,[5] among other things.

    Alternatively, it's possible that what's actually important is HDL functionality, rather than merely HDL levels. According to this hypothesis, some HDL particles have protective effects (e.g., removing cholesterol from arteries), whereas some HDL particles may actually have harmful effects (e.g., promoting inflammation).[6] As a result, increasing HDL-C levels won't reduce the risk of CVD unless it reliably increases the protective functions of HDL particles. However, there is currently much uncertainty regarding these supposedly protective properties of HDL (e.g., how to measure them and how to target them).

    Examine Database: High-density lipoprotein (HDL)

    Berberine
    B
    Small Improvement
    Fish Oil
    B
    Small Improvement
    Curcumin
    B
    Small Improvement
    Saffron
    Spirulina
    Chromium
    Panax Ginseng (Korean Ginseng)
    Conjugated Linoleic Acid
    Garlic
    Cocoa Extract
    Red Clover Extract
    Resveratrol
    Coenzyme Q10
    Mediterranean Diet
    Beta-glucans
    Policosanol
    Magnesium
    Zinc
    Astaxanthin
    Vitamin C
    Hesperidin
    Tart Cherry Juice
    Red Yeast Rice
    Grape Juice
    Kefir
    Ketogenic Diet
    Cinnamon
    Molecular Hydrogen
    Dill
    Niacin (Vitamin B3)
    DHEA
    Inositol
    16:8 Intermittent Fasting
    Alpha-Linolenic Acid (ALA)
    Paleolithic Diet
    Black seed
    Whey Protein
    Psyllium
    Olive Oil
    Lemon Balm
    Flaxseed
    Vegan Diet
    Ashwagandha
    Vitamin E
    N-Acetylcysteine
    Gymnema Sylvestre
    Resistant Starch
    Potatoes
    Aspartame
    Olive Leaf Extract
    Lactobacillus Reuteri
    HMB
    Vitamin D
    Green Tea Extract
    Grape Seed Extract
    Pycnogenol
    Boron
    Tetradecyl Thioacetic Acid
    Apple Cider Vinegar
    Chlorella
    Royal Jelly
    Blueberry
    Roselle
    Artichoke Extract
    Aloe Vera
    Betaine
    L-Carnitine
    OMAD And 20:4 Intermittent Fasting
    Dietary Approaches to Stop Hypertension (DASH) Diet
    Ephedrine
    Rose Hip
    Hemp Protein
    Folic Acid (Vitamin B9)
    Benfotiamine
    Vitamin K
    Gamma Oryzanol
    Pomegranate seed oil
    Quercetin
    Vanadium
    Krill Oil
    Bitter Cucumber
    Rooibos
    Chia seeds
    Guggul
    Tribulus Terrestris
    African Mango
    Yerba Mate
    Reishi
    Maca
    Pyruvate
    Creatine
    Honey
    Probiotics
    Butcher's broom
    Tongkat Ali
    Eleuthero
    Black Cohosh
    Pueraria Mirifica
    Garcinia
    Amla
    Japanese Knotweed
    Horse Chestnut
    Stinging Nettle
    Ginger
    Bhringaraj
    Jiaogulan
    Milk Protein
    Casein
    Soy Protein
    Theanine
    Phosphatidylserine
    Taurine
    Thiamine (Vitamin B1)
    Yacon
    Pterostilbene
    Theaflavins
    Shilajit
    Caffeine
    Melatonin
    Perilla
    Medium-chain Triglycerides
    Safflower Oil
    Phosphatidylcholine
    Soy Lecithin
    Licorice
    Green Coffee Extract
    Korean black raspberry
    Sea Buckthorn
    Mango
    Microlactin
    Ecklonia Cava
    Stevia
    Coffee
    Fenugreek
    Grapefruit
    Kudzu
    Nattokinase
    Citrulline
    PQQ
    TUDCA
    Cherry Extract
    Docosahexaenoic Acid
    Eicosapentaenoic Acid
    Ellagic Acid
    Evening Primrose Oil
    Inulin
    Nicotinamide Mononucleotide
    Nuts
    Sumac

    Research FeedRead all studies

    References

    1. ^Simha V, Kudva YCHDL Cholesterol Story Is Dead: Long Live HDL!Diabetes.(2016-Oct)
    2. ^Navjot Kaur, Avaneesh Pandey, Harish Negi, Nusrat Shafiq, Srinivas Reddy, Harpreet Kaur, Neelima Chadha, Samir MalhotraEffect of HDL-raising drugs on cardiovascular outcomes: a systematic review and meta-regressionPLoS One.(2014 Apr 11)
    3. ^Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MVEvaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.PLoS Med.(2020-Mar)
    4. ^Ormazabal V, Nair S, Elfeky O, Aguayo C, Salomon C, Zuñiga FAAssociation between insulin resistance and the development of cardiovascular diseaseCardiovasc Diabetol.(2018 Aug 31)
    5. ^O'Donovan G, Stensel D, Hamer M, Stamatakis EThe association between leisure-time physical activity, low HDL-cholesterol and mortality in a pooled analysis of nine population-based cohorts.Eur J Epidemiol.(2017-Jul)
    6. ^Casula M, Colpani O, Xie S, Catapano AL, Baragetti AHDL in Atherosclerotic Cardiovascular Disease: In Search of a Role.Cells.(2021-Jul-23)
    7. ^World Health OrganizationEffects of saturated fatty acids on serum lipids and lipoproteins: a systematic review and regression analysis(2016)
    8. ^McQueen MJ, Hawken S, Wang X, Ounpuu S, Sniderman A, Probstfield J, Steyn K, Sanderson JE, Hasani M, Volkova E, Kazmi K, Yusuf S, INTERHEART study investigatorsLipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control studyLancet.(2008 Jul 19)
    9. ^Walldius G, Jungner I, Aastveit AH, Holme I, Furberg CD, Sniderman ADThe apoB/apoA-I ratio is better than the cholesterol ratios to estimate the balance between plasma proatherogenic and antiatherogenic lipoproteins and to predict coronary riskClin Chem Lab Med.(2004)
    10. ^da Luz PL, Cesena FH, Favarato D, Cerqueira ESComparison of serum lipid values in patients with coronary artery disease at 70 years of ageAm J Cardiol.(2005 Dec 15)
    11. ^da Luz PL, Favarato D, Faria-Neto JR Jr, Lemos P, Chagas ACHigh ratio of triglycerides to HDL-cholesterol predicts extensive coronary diseaseClinics (Sao Paulo).(2008 Aug)
    12. ^Hanak V, Munoz J, Teague J, Stanley A Jr, Bittner VAccuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype BAm J Cardiol.(2004 Jul 15)

    Examine Database References

    1. Grape Juice - Park YK, Lee SH, Park E, Kim JS, Kang MHChanges in antioxidant status, blood pressure, and lymphocyte DNA damage from grape juice supplementationAnn N Y Acad Sci.(2009 Aug)
    2. Ashwagandha - Agnihotri AP, Sontakke SD, Thawani VR, Saoji A, Goswami VSEffects of Withania somnifera in patients of schizophrenia: A randomized, double blind, placebo controlled pilot trial studyIndian J Pharmacol.(2013 Jul)
    3. Grape Juice - O'Byrne DJ, Devaraj S, Grundy SM, Jialal IComparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adultsAm J Clin Nutr.(2002 Dec)
    4. Cocoa Extract - Fraga CG, Actis-Goretta L, Ottaviani JI, Carrasquedo F, Lotito SB, Lazarus S, Schmitz HH, Keen CLRegular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer playersClin Dev Immunol.(2005 Mar)
    5. Fish Oil - Maki KC, Lawless AL, Kelley KM, Dicklin MR, Schild AL, Rains TMPrescription omega-3-acid ethyl esters reduce fasting and postprandial triglycerides and modestly reduce pancreatic β-cell response in subjects with primary hypertriglyceridemiaProstaglandins Leukot Essent Fatty Acids.(2011 Sep-Oct)
    6. L-Carnitine - Hadier M El-Sheikh, Sahar M El-Haggar, Tamer A ElbedewyComparative study to evaluate the effect of l-carnitine plus glimepiride versus glimepiride alone on insulin resistance in type 2 diabetic patientsDiabetes Metab Syndr.(Jan-Feb 2019)
    7. Fish Oil - Paula Simplício da Silva, Mauro Felippe Felix Mediano, Gilberto Marcelo Sperandio da Silva, Patricia Dias de Brito, Claudia Santos de Aguiar Cardoso, Cristiane Fonseca de Almeida, Luiz Henrique Conde Sangenis, Roberta Olmo Pinheiro, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Andrea Silvestre de SousaOmega-3 supplementation on inflammatory markers in patients with chronic Chagas cardiomyopathy: a randomized clinical studyNutr J.(2017 Jun 9)
    8. Black seed - Bin Sayeed MS, Asaduzzaman M, Morshed H, Hossain MM, Kadir MF, Rahman MRThe effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteersJ Ethnopharmacol.(2013 Jul 30)
    9. Royal Jelly - Morita H, Ikeda T, Kajita K, Fujioka K, Mori I, Okada H, Uno Y, Ishizuka TEffect of royal jelly ingestion for six months on healthy volunteersNutr J.(2012 Sep 21)
    10. Conjugated Linoleic Acid - Moloney F, Yeow TP, Mullen A, Nolan JJ, Roche HMConjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitusAm J Clin Nutr.(2004 Oct)
    11. Red Clover Extract - Blakesmith SJ, Lyons-Wall PM, George C, Joannou GE, Petocz P, Samman SEffects of supplementation with purified red clover (Trifolium pratense) isoflavones on plasma lipids and insulin resistance in healthy premenopausal womenBr J Nutr.(2003 Apr)
    12. Black seed - Sabzghabaee AM, Dianatkhah M, Sarrafzadegan N, Asgary S, Ghannadi AClinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, placebo controlled clinical trialMed Arh.(2012)
    13. Red Clover Extract - Chedraui P, San Miguel G, Hidalgo L, Morocho N, Ross SEffect of Trifolium pratense-derived isoflavones on the lipid profile of postmenopausal women with increased body mass indexGynecol Endocrinol.(2008 Nov)
    14. Inositol - Minozzi M, D'Andrea G, Unfer VTreatment of hirsutism with myo-inositol: a prospective clinical studyReprod Biomed Online.(2008 Oct)
    15. Conjugated Linoleic Acid - Nazare JA, de la Perrière AB, Bonnet F, Desage M, Peyrat J, Maitrepierre C, Louche-Pelissier C, Bruzeau J, Goudable J, Lassel T, Vidal H, Laville MDaily intake of conjugated linoleic acid-enriched yoghurts: effects on energy metabolism and adipose tissue gene expression in healthy subjectsBr J Nutr.(2007 Feb)
    16. Curcumin - Yang H, Xu W, Zhou Z, Liu J, Li X, Chen L, Weng J, Yu ZCurcumin attenuates urinary excretion of albumin in type II diabetic patients with enhancing nuclear factor erythroid-derived 2-like 2 (Nrf2) system and repressing inflammatory signaling efficaciesExp Clin Endocrinol Diabetes.(2015 Jun)
    17. Jiaogulan - Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CGAntidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic PatientsEvid Based Complement Alternat Med.(2012)
    18. L-Carnitine - Fabio Galvano, Giovanni Li Volti, Michele Malaguarnera, Teresio Avitabile, Tijana Antic, Marco Vacante, Mariano MalaguarneraEffects of simvastatin and carnitine versus simvastatin on lipoprotein(a) and apoprotein(a) in type 2 diabetes mellitusExpert Opin Pharmacother.(2009 Aug)
    19. Ketogenic Diet - Varady KA, Bhutani S, Klempel MC, Phillips SAImprovements in vascular health by a low-fat diet, but not a high-fat diet, are mediated by changes in adipocyte biologyNutr J.(2011 Jan 20)
    20. Niacin (Vitamin B3) - Blond E, Rieusset J, Alligier M, Lambert-Porcheron S, Bendridi N, Gabert L, Chetiveaux M, Debard C, Chauvin MA, Normand S, Roth H, de Gouville AC, Krempf M, Vidal H, Goudable J, Laville M, “Niacin” Study GroupNicotinic acid effects on insulin sensitivity and hepatic lipid metabolism: an in vivo to in vitro studyHorm Metab Res.(2014 Jun)
    21. Rooibos - Marnewick JL, Rautenbach F, Venter I, Neethling H, Blackhurst DM, Wolmarans P, Macharia MEffects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular diseaseJ Ethnopharmacol.(2011 Jan 7)
    22. HMB - Wei Hung, Tsung-Han Liu, Chung-Yu Chen, Chen-Kang ChangEffect of β-hydroxy-β-methylbutyrate Supplementation During Energy Restriction in Female Judo AthletesJournal of Exercise Science & Fitness.()
    23. Whey Protein - Pal S, Ellis V, Dhaliwal SEffects of whey protein isolate on body composition, lipids, insulin and glucose in overweight and obese individualsBr J Nutr.(2010 Sep)
    24. Astaxanthin - Macdermid JC, Vincent JI, Gan BS, Grewal RA blinded placebo-controlled randomized trial on the use of astaxanthin as an adjunct to splinting in the treatment of carpal tunnel syndromeHand (N Y).(2012 Mar)
    25. Paleolithic Diet - Ehsan Ghaedi, Mohammad Mohammadi, Hamed Mohammadi, Nahid Ramezani-Jolfaie, Janmohamad Malekzadeh, Mahdieh Hosseinzadeh, Amin Salehi-AbargoueiEffects of a Paleolithic Diet on Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsAdv Nutr.(2019 Jul 1)
    26. Spirulina - Zahra Hamedifard, Alireza Milajerdi, Željko Reiner, Mohsen Taghizadeh, Fariba Kolahdooz, Zatollah AsemiThe effects of spirulina on glycemic control and serum lipoproteins in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trialsPhytother Res.(2019 Oct)
    27. Cocoa Extract - Grassi D, Necozione S, Lippi C, Croce G, Valeri L, Pasqualetti P, Desideri G, Blumberg JB, Ferri CCocoa reduces blood pressure and insulin resistance and improves endothelium-dependent vasodilation in hypertensivesHypertension.(2005 Aug)
    28. Spirulina - Elias E Mazokopakis, Maria G Papadomanolaki, Andreas A Fousteris, Dimitrios A Kotsiris, Ioannis M Lampadakis, Emmanuel S GanotakisThe hepatoprotective and hypolipidemic effects of Spirulina ( Arthrospira platensis) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot studyAnn Gastroenterol.(2014)
    29. Chromium - I Kato, J H Vogelman, V Dilman, J Karkoszka, K Frenkel, N P Durr, N Orentreich, P TonioloEffect of supplementation with chromium picolinate on antibody titers to 5-hydroxymethyl uracilEur J Epidemiol.(1998 Sep)
    30. Vitamin C - Mason SA, Della Gatta PA, Snow RJ, Russell AP, Wadley GDAscorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: Findings of a randomized controlled studyFree Radic Biol Med.(2016 Apr)
    31. Olive Oil - Gimeno E, de la Torre-Carbot K, Lamuela-Raventós RM, Castellote AI, Fitó M, de la Torre R, Covas MI, López-Sabater MCChanges in the phenolic content of low density lipoprotein after olive oil consumption in men. A randomized crossover controlled trialBr J Nutr.(2007 Dec)
    32. 16:8 Intermittent Fasting - Kelsey Gabel, Kristin K Hoddy, Nicole Haggerty, Jeehee Song, Cynthia M Kroeger, John F Trepanowski, Satchidananda Panda, Krista A VaradyEffects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot studyNutr Healthy Aging.(2018 Jun 15)
    33. Green Tea Extract - Stendell-Hollis NR, Thomson CA, Thompson PA, Bea JW, Cussler EC, Hakim IAGreen tea improves metabolic biomarkers, not weight or body composition: a pilot study in overweight breast cancer survivorsJ Hum Nutr Diet.(2010 Dec)
    34. Garlic - Ried K, Toben C, Fakler PEffect of garlic on serum lipids: an updated meta-analysisNutr Rev.(2013 May)
    35. Ashwagandha - Auddy, B, et alA Standardized Withania Somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled StudyJ Am Nut Assn.()
    36. Cocoa Extract - Wan Y, Vinson JA, Etherton TD, Proch J, Lazarus SA, Kris-Etherton PMEffects of cocoa powder and dark chocolate on LDL oxidative susceptibility and prostaglandin concentrations in humansAm J Clin Nutr.(2001 Nov)
    37. Vegan Diet - Hana Kahleova, James McCann, Jihad Alwarith, Emilie Rembert, Andrea Tura, Richard Holubkov, Neal D BarnardA plant-based diet in overweight adults in a 16-week randomized clinical trial: The role of dietary acid loadClin Nutr ESPEN.(2021 Aug)
    38. Spirulina - Reihaneh Zeinalian, Mahdieh Abbasalizad Farhangi, Atefeh Shariat, Maryam Saghafi-AslThe effects of Spirulina Platensis on anthropometric indices, appetite, lipid profile and serum vascular endothelial growth factor (VEGF) in obese individuals: a randomized double blinded placebo controlled trialBMC Complement Altern Med.(2017 Apr 21)
    39. Coenzyme Q10 - Gholami M, Zarei P, Sadeghi Sedeh B, Rafiei F, Khosrowbeygi AEffects of coenzyme Q10 supplementation on serum values of adiponectin, leptin, 8-isoprostane and malondialdehyde in women with type 2 diabetesGynecol Endocrinol.(2018 Dec)
    40. Vitamin E - Roberts LJ 2nd, Oates JA, Linton MF, Fazio S, Meador BP, Gross MD, Shyr Y, Morrow JDThe relationship between dose of vitamin E and suppression of oxidative stress in humansFree Radic Biol Med.(2007 Nov 15)
    41. Lactobacillus Reuteri - Jones ML, Martoni CJ, Parent M, Prakash SCholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt formulation in hypercholesterolaemic adultsBr J Nutr.(2012 May)
    42. Kefir - GÖLÜNÜK, S et alEffects of traditional fermented beverages on some blood parameters in aerobic exercises.Biomedical Research.()
    43. Chromium - Sharma S, Agrawal RP, Choudhary M, Jain S, Goyal S, Agarwal VBeneficial effect of chromium supplementation on glucose, HbA1C and lipid variables in individuals with newly onset type-2 diabetesJ Trace Elem Med Biol.(2011 Jul)
    44. Astaxanthin - Saito M, Yoshida K, Saito W, Fujiya A, Ohgami K, Kitaichi N, Tsukahara H, Ishida S, Ohno SAstaxanthin increases choroidal blood flow velocityGraefes Arch Clin Exp Ophthalmol.(2012 Feb)
    45. Curcumin - Panahi Y, Khalili N, Sahebi E, Namazi S, Reiner Ž, Majeed M, Sahebkar ACurcuminoids modify lipid profile in type 2 diabetes mellitus: A randomized controlled trialComplement Ther Med.(2017 Aug)
    46. Cocoa Extract - Lívia de Paula Nogueira, Marcela Paranhos Knibel, Márcia Regina Simas Gonçalves Torres, José Firmino Nogueira Neto, Antonio Felipe SanjulianiConsumption of high-polyphenol dark chocolate improves endothelial function in individuals with stage 1 hypertension and excess body weightInt J Hypertens.(2012)
    47. Chromium - Ghosh D, Bhattacharya B, Mukherjee B, Manna B, Sinha M, Chowdhury J, Chowdhury SRole of chromium supplementation in Indians with type 2 diabetes mellitusJ Nutr Biochem.(2002 Nov)
    48. Psyllium - de Bock M, Derraik JG, Brennan CM, Biggs JB, Smith GC, Cameron-Smith D, Wall CR, Cutfield WSPsyllium supplementation in adolescents improves fat distribution & lipid profile: a randomized, participant-blinded, placebo-controlled, crossover trialPLoS One.(2012)
    49. Saffron - Milajerdi A, Jazayeri S, Hashemzadeh N, Shirzadi E, Derakhshan Z, Djazayeri A, Akhondzadeh SThe effect of saffron (Crocus sativus L.) hydroalcoholic extract on metabolic control in type 2 diabetes mellitus: A triple-blinded randomized clinical trialJ Res Med Sci.(2018 Feb 20)
    50. Royal Jelly - Georgiev DB, Metka M, Huber JC, Goudev AR, Manassiev NEffects of an herbal medication containing bee products on menopausal symptoms and cardiovascular risk markers: results of a pilot open-uncontrolled trialMedGenMed.(2004 Dec 16)
    51. L-Carnitine - Joanna J Samulak, Angelika K Sawicka, Emilia Samborowska, Robert A OlekPlasma Trimethylamine-N-oxide following Cessation of L-carnitine Supplementation in Healthy Aged WomenNutrients.(2019 Jun 13)
    52. Fish Oil - Alison M Hill, Jonathan D Buckley, Karen J Murphy, and Peter RC HoweCombining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factorsThe American Journal of Clinical Nutrition.()
    53. Curcumin - Na LX, Li Y, Pan HZ, Zhou XL, Sun DJ, Meng M, Li XX, Sun CHCurcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trialMol Nutr Food Res.(2013 Sep)
    54. Conjugated Linoleic Acid - Colakoglu S, Colakoglu M, Taneli F, Cetinoz F, Turkmen MCumulative effects of conjugated linoleic acid and exercise on endurance development, body composition, serum leptin and insulin levelsJ Sports Med Phys Fitness.(2006 Dec)
    55. Niacin (Vitamin B3) - Kelly JJ, Lawson JA, Campbell LV, Storlien LH, Jenkins AB, Whitworth JA, O'Sullivan AJEffects of nicotinic acid on insulin sensitivity and blood pressure in healthy subjectsJ Hum Hypertens.(2000 Sep)
    56. PQQ - Harris CB, Chowanadisai W, Mishchuk DO, Satre MA, Slupsky CM, Rucker RBDietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjectsJ Nutr Biochem.(2013 Dec)
    57. Fish Oil - Maki KC, Lawless AL, Kelley KM, Dicklin MR, Kaden VN, Schild AL, Rains TM, Marshall JWEffects of prescription omega-3-acid ethyl esters on fasting lipid profile in subjects with primary hypercholesterolemiaJ Cardiovasc Pharmacol.(2011 Apr)
    58. Theaflavins - Trautwein EA, Du Y, Meynen E, Yan X, Wen Y, Wang H, Molhuizen HOPurified black tea theaflavins and theaflavins/catechin supplements did not affect serum lipids in healthy individuals with mildly to moderately elevated cholesterol concentrationsEur J Nutr.(2010 Feb)
    59. Vanadium - Jacques-Camarena O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF, Medina-Santillán REffect of vanadium on insulin sensitivity in patients with impaired glucose toleranceAnn Nutr Metab.(2008)
    60. Betaine - Olthof MR, van Vliet T, Verhoef P, Zock PL, Katan MBEffect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humansPLoS Med.(2005 May)
    61. Reishi - Chu TT, Benzie IF, Lam CW, Fok BS, Lee KK, Tomlinson BStudy of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trialBr J Nutr.(2012 Apr)
    62. Ketogenic Diet - Partsalaki I, Karvela A, Spiliotis BEMetabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescentsJ Pediatr Endocrinol Metab.(2012)
    63. Red Clover Extract - Clifton-Bligh PB, Baber RJ, Fulcher GR, Nery ML, Moreton TThe effect of isoflavones extracted from red clover (Rimostil) on lipid and bone metabolismMenopause.(2001 Jul-Aug)
    64. Curcumin - Akazawa N, Choi Y, Miyaki A, Tanabe Y, Sugawara J, Ajisaka R, Maeda SCurcumin ingestion and exercise training improve vascular endothelial function in postmenopausal womenNutr Res.(2012 Oct)
    65. OMAD And 20:4 Intermittent Fasting - Sutton EF, Beyl R, Early KS, Cefalu WT, Ravussin E, Peterson CMEarly Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with PrediabetesCell Metab.(2018 Jun 5)
    66. Pycnogenol - Devaraj S, Vega-López S, Kaul N, Schönlau F, Rohdewald P, Jialal ISupplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profileLipids.(2002 Oct)
    67. Shilajit - Sharma P, Jha J, Shrinivas V, Dwivedi LK, Suresh P, Sinha MShilajit: evalution of its effects on blood chemistry of normal human subjectsAnc Sci Life.(2003 Oct)
    68. Curcumin - Panahi Y, Kianpour P, Mohtashami R, Jafari R, Simental-Mendía LE, Sahebkar ACurcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled TrialJ Cardiovasc Pharmacol.(2016 Sep)
    69. Berberine - Derosa G, D'Angelo A, Bonaventura A, Bianchi L, Romano D, Maffioli PEffects of berberine on lipid profile in subjects with low cardiovascular riskExpert Opin Biol Ther.(2013 Apr)
    70. Ketogenic Diet - Volek JS, Sharman MJ, Gómez AL, DiPasquale C, Roti M, Pumerantz A, Kraemer WJComparison of a very low-carbohydrate and low-fat diet on fasting lipids, LDL subclasses, insulin resistance, and postprandial lipemic responses in overweight womenJ Am Coll Nutr.(2004 Apr)
    71. Green Coffee Extract - Watanabe T, Arai Y, Mitsui Y, Kusaura T, Okawa W, Kajihara Y, Saito IThe blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertensionClin Exp Hypertens.(2006 Jul)
    72. Cocoa Extract - Di Renzo L, Rizzo M, Sarlo F, Colica C, Iacopino L, Domino E, Sergi D, De Lorenzo AEffects of dark chocolate in a population of normal weight obese women: a pilot studyEur Rev Med Pharmacol Sci.(2013 Aug)
    73. Ketogenic Diet - Yancy WS Jr, Westman EC, McDuffie JR, Grambow SC, Jeffreys AS, Bolton J, Chalecki A, Oddone EZA randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight lossArch Intern Med.(2010 Jan 25)
    74. Curcumin - Ferguson JJA, Wolska A, Remaley AT, Stojanovski E, MacDonald-Wicks L, Garg MLBread enriched with phytosterols with or without curcumin modulates lipoprotein profiles in hypercholesterolaemic individuals. A randomised controlled trialFood Funct.(2019 May 22)
    75. Blueberry - Arpita Basu, Mei Du, Misti J Leyva, Karah Sanchez, Nancy M Betts, Mingyuan Wu, Christopher E Aston, Timothy J LyonsBlueberries decrease cardiovascular risk factors in obese men and women with metabolic syndromeJ Nutr.(2010 Sep)
    76. Garlic - Budoff MJ, Takasu J, Flores FR, Niihara Y, Lu B, Lau BH, Rosen RT, Amagase HInhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary studyPrev Med.(2004 Nov)
    77. Niacin (Vitamin B3) - AIM-HIGH Investigators, Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub WNiacin in patients with low HDL cholesterol levels receiving intensive statin therapyN Engl J Med.(2011 Dec 15)
    78. Paleolithic Diet - Barbara Frączek, Aleksandra Pięta, Adrian Burda, Paulina Mazur-Kurach, Florentyna TyrałaPaleolithic Diet-Effect on the Health Status and Performance of Athletes?Nutrients.(2021 Mar 21)
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    81. Tetradecyl Thioacetic Acid - Reidar J Pettersen, Mohamed Salem, Jon Skorve, Rune J Ulvik, Rolf K Berge, Jan Erik NordrehaugPharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 studyJ Cardiovasc Pharmacol.(2008 Apr)
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    83. Coenzyme Q10 - Abdollahzad H, et alCoenzyme Q10 supplementation in patients with rheumatoid arthritis: Are there any effects on cardiovascular risk factors?Eur J Integr Med..()
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    89. Pyruvate - Stanko RT, Reynolds HR, Lonchar KD, Arch JEPlasma lipid concentrations in hyperlipidemic patients consuming a high-fat diet supplemented with pyruvate for 6 wkAm J Clin Nutr.(1992 Nov)
    90. Olive Oil - Weinbrenner T, Fitó M, de la Torre R, Saez GT, Rijken P, Tormos C, Coolen S, Albaladejo MF, Abanades S, Schroder H, Marrugat J, Covas MIOlive oils high in phenolic compounds modulate oxidative/antioxidative status in menJ Nutr.(2004 Sep)
    91. Saffron - Fatemeh Ebrahimi, Amirhossein Sahebkar, Naheed Aryaeian, Naseh Pahlavani, Soudabeh Fallah, Nariman Moradi, Davoud Abbasi, Agha Fatemeh HosseiniEffects Of Saffron Supplementation On Inflammation And Metabolic Responses In Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled TrialDiabetes Metab Syndr Obes.(2019 Oct 14)
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    93. Kefir - Alireza Ostadrahimi, Akbar Taghizadeh, Majid Mobasseri, Nazila Farrin, Laleh Payahoo, Zahra Beyramalipoor Gheshlaghi, Morteza VahedjabbariEffect of probiotic fermented milk (kefir) on glycemic control and lipid profile in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trialIran J Public Health.(2015 Feb)
    94. Bhringaraj - Vasavi Rangineni, D Sharada, Saileshnath SaxenaDiuretic, hypotensive, and hypocholesterolemic effects of Eclipta alba in mild hypertensive subjects: a pilot studyJ Med Food.(2007 Mar)
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    96. Conjugated Linoleic Acid - Sluijs I, Plantinga Y, de Roos B, Mennen LI, Bots MLDietary supplementation with cis-9,trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adultsAm J Clin Nutr.(2010 Jan)
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    99. Caffeine - Wedick NM, Brennan AM, Sun Q, Hu FB, Mantzoros CS, van Dam RMEffects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes: a randomized controlled trialNutr J.(2011 Sep 13)
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    105. Vitamin E - Singh I, Turner AH, Sinclair AJ, Li D, Hawley JAEffects of gamma-tocopherol supplementation on thrombotic risk factorsAsia Pac J Clin Nutr.(2007)
    106. Coffee - Kempf K, Herder C, Erlund I, Kolb H, Martin S, Carstensen M, Koenig W, Sundvall J, Bidel S, Kuha S, Tuomilehto JEffects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trialAm J Clin Nutr.(2010 Apr)
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    139. Pueraria Mirifica - Okamura S, Sawada Y, Satoh T, Sakamoto H, Saito Y, Sumino H, Takizawa T, Kogure T, Chaichantipyuth C, Higuchi Y, Ishikawa T, Sakamaki TPueraria mirifica phytoestrogens improve dyslipidemia in postmenopausal women probably by activating estrogen receptor subtypesTohoku J Exp Med.(2008 Dec)
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    159. Cocoa Extract - Engler MB, Engler MM, Chen CY, Malloy MJ, Browne A, Chiu EY, Kwak HK, Milbury P, Paul SM, Blumberg J, Mietus-Snyder MLFlavonoid-rich dark chocolate improves endothelial function and increases plasma epicatechin concentrations in healthy adultsJ Am Coll Nutr.(2004 Jun)
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    188. Olive Oil - Marrugat J, Covas MI, Fitó M, Schröder H, Miró-Casas E, Gimeno E, López-Sabater MC, de la Torre R, Farré M; SOLOS InvestigatorsEffects of differing phenolic content in dietary olive oils on lipids and LDL oxidation--a randomized controlled trialEur J Nutr.(2004 Jun)
    189. Grape Juice - Castilla P, Echarri R, Dávalos A, Cerrato F, Ortega H, Teruel JL, Lucas MF, Gómez-Coronado D, Ortuño J, Lasunción MAConcentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjectsAm J Clin Nutr.(2006 Jul)
    190. Policosanol - Swanson B, Keithley JK, Sha BE, Fogg L, Nerad J, Novak RM, Adeyemi O, Spear GTPolicosanol for managing human immunodeficiency virus-related dyslipidemia in a medically underserved population: a randomized, controlled clinical trialAltern Ther Health Med.(2011 Mar-Apr)
    191. Microlactin - Sharpe SJ, Gamble GD, Sharpe DNCholesterol-lowering and blood pressure effects of immune milkAm J Clin Nutr.(1994 Apr)
    192. Curcumin - Mirzabeigi P, Mohammadpour AH, Salarifar M, Gholami K, Mojtahedzadeh M, Javadi MRThe Effect of Curcumin on some of Traditional and Non-traditional Cardiovascular Risk Factors: A Pilot Randomized, Double-blind, Placebo-controlled TrialIran J Pharm Res.(2015 Spring)
    193. Berberine - Yan HM, Xia MF, Wang Y, Chang XX, Yao XZ, Rao SX, Zeng MS, Tu YF, Feng R, Jia WP, Liu J, Deng W, Jiang JD, Gao XEfficacy of Berberine in Patients with Non-Alcoholic Fatty Liver DiseasePLoS One.(2015 Aug 7)
    194. 16:8 Intermittent Fasting - Grant M Tinsley, M Lane Moore, Austin J Graybeal, Antonio Paoli, Youngdeok Kim, Joaquin U Gonzales, John R Harry, Trisha A VanDusseldorp, Devin N Kennedy, Megan R CruzTime-restricted feeding plus resistance training in active females: a randomized trialAm J Clin Nutr.(2019 Sep 1)
    195. Cocoa Extract - Balzer J, Rassaf T, Heiss C, Kleinbongard P, Lauer T, Merx M, Heussen N, Gross HB, Keen CL, Schroeter H, Kelm MSustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trialJ Am Coll Cardiol.(2008 Jun 3)
    196. Hesperidin - Miwa Y, Mitsuzumi H, Sunayama T, Yamada M, Okada K, Kubota M, Chaen H, Mishima Y, Kibata MGlucosyl hesperidin lowers serum triglyceride level in hypertriglyceridemic subjects through the improvement of very low-density lipoprotein metabolic abnormalityJ Nutr Sci Vitaminol (Tokyo).(2005 Dec)
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    199. Fish Oil - Zulyniak MA, Perreault M, Gerling C, Spriet LL, Mutch DMFish oil supplementation alters circulating eicosanoid concentrations in young healthy menMetabolism.(2013 Mar 20)
    200. Niacin (Vitamin B3) - Westphal S, Borucki K, Taneva E, Makarova R, Luley CExtended-release niacin raises adiponectin and leptinAtherosclerosis.(2007 Aug)
    201. Zinc - Kelishadi R, Hashemipour M, Adeli K, Tavakoli N, Movahedian-Attar A, Shapouri J, Poursafa P, Rouzbahani AEffect of zinc supplementation on markers of insulin resistance, oxidative stress, and inflammation among prepubescent children with metabolic syndromeMetab Syndr Relat Disord.(2010 Dec)
    202. Amla - Muhammad Shoaib Akhtar, Ayesha Ramzan, Amanat Ali, Maqsood AhmadEffect of Amla fruit (Emblica officinalis Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patientsInt J Food Sci Nutr.(2011 Sep)
    203. Niacin (Vitamin B3) - Valeria Nasser Figueiredo, Felipe Vendrame, Bruno A Colontoni, Thiago Quinaglia, Jose Roberto Matos-Souza, Filipe Azevedo Moura, Otavio R Coelho, Eliana C de Faria, Andrei C SpositoShort-term effects of extended-release niacin with and without the addition of laropiprant on endothelial function in individuals with low HDL-C: a randomized, controlled crossover trialClin Ther.(2014 Jun 1)
    204. Saffron - Soukhtanloo M, et alEffect of saffron on serum leptin levels in patients with metabolic syndrome, a double-blind, randomized and placebo-controlled trial studyProg Nutr.()
    205. Medium-chain Triglycerides - Han JR, Deng B, Sun J, Chen CG, Corkey BE, Kirkland JL, Ma J, Guo WEffects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjectsMetabolism.(2007 Jul)
    206. Niacin (Vitamin B3) - T Sakai, V S Kamanna, M L KashyapNiacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterolArterioscler Thromb Vasc Biol.(2001 Nov)
    207. Fish Oil - Warner JG Jr, Ullrich IH, Albrink MJ, Yeater RACombined effects of aerobic exercise and omega-3 fatty acids in hyperlipidemic personsMed Sci Sports Exerc.(1989 Oct)
    208. Vitamin C - Kim MK, Sasaki S, Sasazuki S, Okubo S, Hayashi M, Tsugane SLong-term vitamin C supplementation has no markedly favourable effect on serum lipids in middle-aged Japanese subjectsBr J Nutr.(2004 Jan)
    209. Ketogenic Diet - Parker N Hyde, Teryn N Sapper, Christopher D Crabtree, Richard A LaFountain, Madison L Bowling, Alex Buga, Brandon Fell, Fionn T McSwiney, Ryan M Dickerson, Vincent J Miller, Debbie Scandling, Orlando P Simonetti, Stephen D Phinney, William J Kraemer, Sarah A King, Ronald M Krauss, Jeff S VolekDietary carbohydrate restriction improves metabolic syndrome independent of weight lossJCI Insight.(2019 Jun 20)
    210. Theanine - Shinsuke Hidese, Miho Ota, Chisato Wakabayashi, Takamasa Noda, Hayato Ozawa, Tsutomu Okubo, Hiroshi KunugiEffects of chronic l-theanine administration in patients with major depressive disorder: an open-label studyActa Neuropsychiatr.(2017 Apr)
    211. Policosanol - Francini-Pesenti F, Beltramolli D, Dall'acqua S, Brocadello FEffect of sugar cane policosanol on lipid profile in primary hypercholesterolemiaPhytother Res.(2008 Mar)
    212. Spirulina - Parikh P, Mani U, Iyer URole of Spirulina in the Control of Glycemia and Lipidemia in Type 2 Diabetes MellitusJ Med Food.(2001 Winter)
    213. Grape Seed Extract - Sivaprakasapillai B, Edirisinghe I, Randolph J, Steinberg F, Kappagoda TEffect of grape seed extract on blood pressure in subjects with the metabolic syndromeMetabolism.(2009 Dec)
    214. DHEA - Igwebuike A, Irving BA, Bigelow ML, Short KR, McConnell JP, Nair KSLack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal womenJ Clin Endocrinol Metab.(2008 Feb)
    215. Yerba Mate - de Morais EC, Stefanuto A, Klein GA, Boaventura BC, de Andrade F, Wazlawik E, Di Pietro PF, Maraschin M, da Silva ELConsumption of yerba mate ( Ilex paraguariensis ) improves serum lipid parameters in healthy dyslipidemic subjects and provides an additional LDL-cholesterol reduction in individuals on statin therapyJ Agric Food Chem.(2009 Sep 23)
    216. Guggul - Szapary PO, Wolfe ML, Bloedon LT, Cucchiara AJ, DerMarderosian AH, Cirigliano MD, Rader DJGuggulipid for the treatment of hypercholesterolemia: a randomized controlled trialJAMA.(2003 Aug 13)
    217. Garlic - Sobenin IA, Pryanishnikov VV, Kunnova LM, Rabinovich YA, Martirosyan DM, Orekhov ANThe effects of time-released garlic powder tablets on multifunctional cardiovascular risk in patients with coronary artery diseaseLipids Health Dis.(2010 Oct 19)
    218. L-Carnitine - Eun Shil Hong, Eun Ky Kim, Seon Mee Kang, Ah Reum Khang, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Soo LimEffect of carnitine-orotate complex on glucose metabolism and fatty liver: a double-blind, placebo-controlled studyJ Gastroenterol Hepatol.(2014)
    219. L-Carnitine - Jun-jie Zhang, Zhi-bing Wu, You-jin Cai, Bin Ke, Ying-juan Huang, Chao-ping Qiu, Yu-bing Yang, Lan-ying Shi, Jian QinL-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled studyNutr J.(2014 Nov 26)
    220. Vitamin D - Seibert E, Lehmann U, Riedel A, Ulrich C, Hirche F, Brandsch C, Dierkes J, Girndt M, Stangl GIVitamin D3 supplementation does not modify cardiovascular risk profile of adults with inadequate vitamin D statusEur J Nutr.(2015 Nov 30)
    221. Spirulina - Patricia V Torres-Duran, Aldo Ferreira-Hermosillo, Marco A Juarez-OropezaAntihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary reportLipids Health Dis.(2007 Nov 26)
    222. Cocoa Extract - Davison K, Coates AM, Buckley JD, Howe PREffect of cocoa flavanols and exercise on cardiometabolic risk factors in overweight and obese subjectsInt J Obes (Lond).(2008 Aug)
    223. Astaxanthin - Baralic I, Andjelkovic M, Djordjevic B, Dikic N, Radivojevic N, Suzin-Zivkovic V, Radojevic-Skodric S, Pejic SEffect of Astaxanthin Supplementation on Salivary IgA, Oxidative Stress, and Inflammation in Young Soccer PlayersEvid Based Complement Alternat Med.(2015)
    224. Nattokinase - Yang NC, Chou CW, Chen CY, Hwang KL, Yang YCCombined nattokinase with red yeast rice but not nattokinase alone has potent effects on blood lipids in human subjects with hyperlipidemia.Asia Pac J Clin Nutr.(2009)
    225. Magnesium - Guerrero-Romero F, Rodríguez-Morán MThe effect of lowering blood pressure by magnesium supplementation in diabetic hypertensive adults with low serum magnesium levels: a randomized, double-blind, placebo-controlled clinical trialJ Hum Hypertens.(2009 Apr)
    226. Ashwagandha - Raut AA, Rege NN, Tadvi FM, Solanki PV, Kene KR, Shirolkar SG, Pandey SN, Vaidya RA, Vaidya ABExploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteersJ Ayurveda Integr Med.(2012 Jul)
    227. Garlic - Sobenin IA, Andrianova IV, Demidova ON, Gorchakova T, Orekhov ANLipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized studyJ Atheroscler Thromb.(2008 Dec)
    228. Berberine - Dong H, Wang N, Zhao L, Lu FBerberine in the treatment of type 2 diabetes mellitus: a systemic review and meta-analysisEvid Based Complement Alternat Med.(2012)
    229. Creatine - Earnest CP, Almada AL, Mitchell TLHigh-performance capillary electrophoresis-pure creatine monohydrate reduces blood lipids in men and womenClin Sci (Lond).(1996 Jul)
    230. Garlic - Adler AJ, Holub BJEffect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic menAm J Clin Nutr.(1997 Feb)
    231. Fish Oil - Ilowite NT, Copperman N, Leicht T, Kwong T, Jacobson MSEffects of dietary modification and fish oil supplementation on dyslipoproteinemia in pediatric systemic lupus erythematosusJ Rheumatol.(1995 Jul)
    232. Spirulina - R Samuels, U V Mani, U M Iyer, U S NayakHypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndromeJ Med Food.(Summer 2002)
    233. Policosanol - Illnait J, Castaño G, Alvarez E, Fernández L, Mas R, Mendoza S, Gamez REffects of policosanol (10 mg/d) versus aspirin (100 mg/d) in patients with intermittent claudication: a 10-week, randomized, comparative studyAngiology.(2008 Jun-Jul)
    234. Phosphatidylserine - Kato-Kataoka A, Sakai M, Ebina R, Nonaka C, Asano T, Miyamori TSoybean-derived phosphatidylserine improves memory function of the elderly Japanese subjects with memory complaintsJ Clin Biochem Nutr.(2010 Nov)
    235. Saffron - Babak Roshanravan, Saeed Samarghandian, Milad Ashrafizadeh, Alireza Amirabadizadeh, Farhad Saeedi, Tahereh FarkhondehMetabolic Impact of Saffron and Crocin: An Updated Systematic and Meta-Analysis of Randomised Clinical TrialsArch Physiol Biochem.(2020 Feb 4)
    236. Chromium - Aghdassi E, Arendt BM, Salit IE, Mohammed SS, Jalali P, Bondar H, Allard JPIn patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trialCurr HIV Res.(2010 Mar)
    237. DHEA - Jedrzejuk D, Medras M, Milewicz A, Demissie MDehydroepiandrosterone replacement in healthy men with age-related decline of DHEA-S: effects on fat distribution, insulin sensitivity and lipid metabolismAging Male.(2003 Sep)
    238. Black seed - Kalus U, Pruss A, Bystron J, Jurecka M, Smekalova A, Lichius JJ, Kiesewetter HEffect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseasesPhytother Res.(2003 Dec)
    239. Tribulus Terrestris - Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SHEfficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes MellitusIran J Med Sci.(2016 May)
    240. Resveratrol - Magyar K, Halmosi R, Palfi A, Feher G, Czopf L, Fulop A, Battyany I, Sumegi B, Toth K, Szabados ECardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery diseaseClin Hemorheol Microcirc.(2012 Jan 1)
    241. Cocoa Extract - Grassi D, Lippi C, Necozione S, Desideri G, Ferri CShort-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy personsAm J Clin Nutr.(2005 Mar)
    242. Conjugated Linoleic Acid - Tricon S, Burdge GC, Jones EL, Russell JJ, El-Khazen S, Moretti E, Hall WL, Gerry AB, Leake DS, Grimble RF, Williams CM, Calder PC, Yaqoob PEffects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged menAm J Clin Nutr.(2006 Apr)
    243. Chromium - Racek J, Trefil L, Rajdl D, Mudrová V, Hunter D, Senft VInfluence of chromium-enriched yeast on blood glucose and insulin variables, blood lipids, and markers of oxidative stress in subjects with type 2 diabetes mellitusBiol Trace Elem Res.(2006 Mar)
    244. Red Clover Extract - Schult TM, Ensrud KE, Blackwell T, Ettinger B, Wallace R, Tice JAEffect of isoflavones on lipids and bone turnover markers in menopausal womenMaturitas.(2004 Jul 15)
    245. Grape Juice - Hollis JH, Houchins JA, Blumberg JB, Mattes RDEffects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adultsJ Am Coll Nutr.(2009 Oct)
    246. Green Tea Extract - Hsu CH, Tsai TH, Kao YH, Hwang KC, Tseng TY, Chou PEffect of green tea extract on obese women: a randomized, double-blind, placebo-controlled clinical trialClin Nutr.(2008 Jun)
    247. Vitamin E - Meydani SN, Meydani M, Blumberg JB, Leka LS, Pedrosa M, Diamond R, Schaefer EJAssessment of the safety of supplementation with different amounts of vitamin E in healthy older adultsAm J Clin Nutr.(1998 Aug)
    248. Spirulina - Marco Antonio Hernández-Lepe, Abraham Wall-Medrano, José Alberto López-Díaz, Marco Antonio Juárez-Oropeza, Rosa Patricia Hernández-Torres, Arnulfo Ramos-JiménezHypolipidemic Effect of Arthrospira ( Spirulina) maxima Supplementation and a Systematic Physical Exercise Program in Overweight and Obese Men: A Double-Blind, Randomized, and Crossover Controlled TrialMar Drugs.(2019 May 7)
    249. Berberine - Pérez-Rubio KG, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA, Espinel-Bermúdez MCEffect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretionMetab Syndr Relat Disord.(2013 Oct)
    250. Fish Oil - Fakhrzadeh H, Ghaderpanahi M, Sharifi F, Mirarefin M, Badamchizade Z, Kamrani AA, Larijani BThe effects of low dose n-3 fatty acids on serum lipid profiles and insulin resistance of the elderly: a randomized controlled clinical trialInt J Vitam Nutr Res.(2010 Apr)
    251. Soy Lecithin - Mourad AM, de Carvalho Pincinato E, Mazzola PG, Sabha M, Moriel PInfluence of soy lecithin administration on hypercholesterolemiaCholesterol.(2010)
    252. Ephedrine - Boozer CN, Daly PA, Homel P, Solomon JL, Blanchard D, Nasser JA, Strauss R, Meredith THerbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trialInt J Obes Relat Metab Disord.(2002 May)
    253. Ketogenic Diet - Boden G, Sargrad K, Homko C, Mozzoli M, Stein TPEffect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetesAnn Intern Med.(2005 Mar 15)
    254. Dill - Kojuri J, Vosoughi AR, Akrami MEffects of anethum graveolens and garlic on lipid profile in hyperlipidemic patientsLipids Health Dis.(2007 Mar 1)
    255. Red Clover Extract - Atkinson C, Oosthuizen W, Scollen S, Loktionov A, Day NE, Bingham SAModest protective effects of isoflavones from a red clover-derived dietary supplement on cardiovascular disease risk factors in perimenopausal women, and evidence of an interaction with ApoE genotype in 49-65 year-old womenJ Nutr.(2004 Jul)
    256. Gamma Oryzanol - Berger A, Rein D, Schäfer A, Monnard I, Gremaud G, Lambelet P, Bertoli CSimilar cholesterol-lowering properties of rice bran oil, with varied gamma-oryzanol, in mildly hypercholesterolemic menEur J Nutr.(2005 Mar)
    257. Royal Jelly - Hang Guo, Ai Saiga, Mikako Sato, Izumi Miyazawa, Makoto Shibata, Yoshihisa Takahata, Fumiki MorimatsuRoyal jelly supplementation improves lipoprotein metabolism in humansJ Nutr Sci Vitaminol (Tokyo).(2007 Aug)
    258. L-Carnitine - Vincenzo Solfrizzi, Cristiano Capurso, Anna M Colacicco, Alessia D'Introno, Cristina Fontana, Sabrina A Capurso, Francesco Torres, Anna M Gadaleta, Aleardo Koverech, Antonio Capurso, Francesco PanzaEfficacy and tolerability of combined treatment with L-carnitine and simvastatin in lowering lipoprotein(a) serum levels in patients with type 2 diabetes mellitusAtherosclerosis.(2006 Oct)
    259. African Mango - Ngondi JL, Oben JE, Minka SRThe effect of Irvingia gabonensis seeds on body weight and blood lipids of obese subjects in CameroonLipids Health Dis.(2005 May 25)
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    261. Krill Oil - Bunea R, El Farrah K, Deutsch LEvaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemiaAltern Med Rev.(2004 Dec)
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    263. Kefir - Yasamin Fathi, Shiva Faghih, Mohammad Javad Zibaeenezhad, Sayed Hamid Reza TabatabaeiKefir drink leads to a similar weight loss, compared with milk, in a dairy-rich non-energy-restricted diet in overweight or obese premenopausal women: a randomized controlled trialEur J Nutr.(2016 Feb)
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    266. Bitter Cucumber - Rahbar AR, Nabipour IThe hypolipidemic effect of Citrullus colocynthis on patients with hyperlipidemiaPak J Biol Sci.(2010 Dec 15)
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    268. OMAD And 20:4 Intermittent Fasting - Stote KS, Baer DJ, Spears K, Paul DR, Harris GK, Rumpler WV, Strycula P, Najjar SS, Ferrucci L, Ingram DK, Longo DL, Mattson MPA controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adultsAm J Clin Nutr.(2007 Apr)
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    273. Olive Oil - Castañer O, Covas MI, Khymenets O, Nyyssonen K, Konstantinidou V, Zunft HF, de la Torre R, Muñoz-Aguayo D, Vila J, Fitó MProtection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humansAm J Clin Nutr.(2012 May)
    274. Inositol - Gerli S, Mignosa M, Di Renzo GCEffects of inositol on ovarian function and metabolic factors in women with PCOS: a randomized double blind placebo-controlled trialEur Rev Med Pharmacol Sci.(2003 Nov-Dec)
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    285. Boron - Rogoveanu OC, Mogoşanu GD, Bejenaru C, Bejenaru LE, Croitoru O, Neamţu J, Pietrzkowski Z, Reyes-Izquierdo T, Biţă A, Scorei ID, Scorei RIEffects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical StudyBiol Trace Elem Res.(2015 Feb)
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    288. Rooibos - Débora Villaño, Monia Pecorari, Maria Francesca Testa, Anna Raguzzini, Angelique Stalmach, Alan Crozier, Claudio Tubili, Mauro SerafiniUnfermented and fermented rooibos teas (Aspalathus linearis) increase plasma total antioxidant capacity in healthy humansFood Chemistry.()
    289. Chromium - Iqbal N, Cardillo S, Volger S, Bloedon LT, Anderson RA, Boston R, Szapary POChromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adultsMetab Syndr Relat Disord.(2009 Apr)
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    291. Vegan Diet - Ann-Charlotte Elkan, Beatrice Sjöberg, Björn Kolsrud, Bo Ringertz, Ingiäld Hafström, Johan FrostegårdGluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized studyArthritis Res Ther.(2008)
    292. Hesperidin - Rizza S, Muniyappa R, Iantorno M, Kim JA, Chen H, Pullikotil P, Senese N, Tesauro M, Lauro D, Cardillo C, Quon MJCitrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndromeJ Clin Endocrinol Metab.(2011 May)
    293. Curcumin - Campbell MS, Ouyang A, I M K, Charnigo RJ, Westgate PM, Fleenor BSInfluence of enhanced bioavailable curcumin on obesity-associated cardiovascular disease risk factors and arterial function: A double-blinded, randomized, controlled trialNutrition.(2019 Jun)
    294. Ketogenic Diet - Keogh JB, Brinkworth GD, Noakes M, Belobrajdic DP, Buckley JD, Clifton PMEffects of weight loss from a very-low-carbohydrate diet on endothelial function and markers of cardiovascular disease risk in subjects with abdominal obesityAm J Clin Nutr.(2008 Mar)
    295. Vitamin C - Gutierrez AD, Duran-Valdez E, Robinson I, de Serna DG, Schade DSDoes short-term vitamin C reduce cardiovascular risk in type 2 diabetes?Endocr Pract.(2013 Sep-Oct)
    296. Saffron - Mostafa Asadollahi, Parisa Nikdokht, Boshra Hatef, Seyed Shahabeddin Sadr, Hedayat Sahraei, Farhad Assarzadegan, Gila Pirzad JahromiProtective properties of the aqueous extract of saffron (Crocus sativus L.) in ischemic stroke, randomized clinical trialJ Ethnopharmacol.(2019 Jun 28)
    297. Conjugated Linoleic Acid - Sato K, Shinohara N, Honma T, Ito J, Arai T, Nosaka N, Aoyama T, Tsuduki T, Ikeda IThe change in conjugated linoleic acid concentration in blood of Japanese fed a conjugated linoleic acid dietJ Nutr Sci Vitaminol (Tokyo).(2011)
    298. Fish Oil - Goh YK, Jumpsen JA, Ryan EA, Clandinin MTEffect of omega 3 fatty acid on plasma lipids, cholesterol and lipoprotein fatty acid content in NIDDM patientsDiabetologia.(1997 Jan)
    299. Curcumin - Funamoto M, Sunagawa Y, Katanasaka Y, Miyazaki Y, Imaizumi A, Kakeya H, Yamakage H, Satoh-Asahara N, Komiyama M, Wada H, Hasegawa K, Morimoto THighly absorptive curcumin reduces serum atherosclerotic low-density lipoprotein levels in patients with mild COPDInt J Chron Obstruct Pulmon Dis.(2016 Aug 26)
    300. Zinc - Seet RC, Lee CY, Lim EC, Quek AM, Huang H, Huang SH, Looi WF, Long LH, Halliwell BOral zinc supplementation does not improve oxidative stress or vascular function in patients with type 2 diabetes with normal zinc levelsAtherosclerosis.(2011 Nov)
    301. Fish Oil - L Axelrod, J Camuso, E Williams, K Kleinman, E Briones, D SchoenfeldEffects of a Small Quantity of omega-3 Fatty Acids on Cardiovascular Risk Factors in NIDDM. A Randomized, Prospective, Double-Blind, Controlled StudyDiabetes Care.(1994 Jan)
    302. Licorice - Bell ZW, Canale RE, Bloomer RJA dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers of health and adiposityLipids Health Dis.(2011 Feb 10)
    303. L-Carnitine - Aneliya Parvanova, Matias Trillini, Manuel A Podestà, Ilian P Iliev, Carolina Aparicio, Annalisa Perna, Francesco Peraro, Nadia Rubis, Flavio Gaspari, Antonio Cannata, Silvia Ferrari, Antonio C Bossi, Roberto Trevisan, Sreejith Parameswaran, Jonathan S Chávez-Iñiguez, Fahrudin Masnic, Sidy Mohamed Seck, Teerayuth Jiamjariyaporn, Monica Cortinovis, Luca Perico, Kanishka Sharma, Giuseppe Remuzzi, Piero Ruggenenti, David G WarnockBlood Pressure and Metabolic Effects of Acetyl-l-Carnitine in Type 2 Diabetes: DIABASI Randomized Controlled TrialJ Endocr Soc.(2018 Mar 22)
    304. Apple Cider Vinegar - Oanetta, C. Jonk, Y, Shapiro, AProspective randomized clinical trial evaluating the impact of vinegar on lipids in non-diabeticsWorld J. Cardiovasc. Dis.()
    305. DHEA - Libè R, Barbetta L, Dall'Asta C, Salvaggio F, Gala C, Beck-Peccoz P, Ambrosi BEffects of dehydroepiandrosterone (DHEA) supplementation on hormonal, metabolic and behavioral status in patients with hypoadrenalismJ Endocrinol Invest.(2004 Sep)
    306. African Mango - Ngondi JL, Etoundi BC, Nyangono CB, Mbofung CM, Oben JEIGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigationLipids Health Dis.(2009 Mar 2)
    307. Kefir - TAREK A. EL-BASHITI, BAKER M. ZABUT and FEDAA F. ABU SAFIAEffect of Probiotic Fermented Milk (Kefir) on Some Blood Biochemical Parameters Among Newly Diagnosed Type 2 Diabetic Adult Males in Gaza GovernorateCurrent Research in Nutrition and Food Science.()
    308. Mango - Shirley F Evans, Maureen Meister, Maryam Mahmood, Heba Eldoumi, Sandra Peterson, Penelope Perkins-Veazie, Stephen L Clarke, Mark Payton, Brenda J Smith, Edralin A LucasMango supplementation improves blood glucose in obese individualsNutr Metab Insights.(2014 Aug 28)
    309. L-Carnitine - Sani Hlais, Dana R Abou Reslan, Hiba K Sarieddine, Lara Nasreddine, Ghazi Taan, Sami Azar, Omar A ObeidEffect of lysine, vitamin B(6), and carnitine supplementation on the lipid profile of male patients with hypertriglyceridemia: a 12-week, open-label, randomized, placebo-controlled trialClin Ther.(2012 Aug)
    310. Curcumin - Panahi Y, Khalili N, Hosseini MS, Abbasinazari M, Sahebkar ALipid-modifying effects of adjunctive therapy with curcuminoids-piperine combination in patients with metabolic syndrome: results of a randomized controlled trialComplement Ther Med.(2014 Oct)
    311. Lactobacillus Reuteri - Wolf BW, Wheeler KB, Ataya DG, Garleb KASafety and tolerance of Lactobacillus reuteri supplementation to a population infected with the human immunodeficiency virusFood Chem Toxicol.(1998 Dec)
    312. Cocoa Extract - Muniyappa R, Hall G, Kolodziej TL, Karne RJ, Crandon SK, Quon MJCocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertensionAm J Clin Nutr.(2008 Dec)
    313. Cocoa Extract - Grassi D, Desideri G, Necozione S, Lippi C, Casale R, Properzi G, Blumberg JB, Ferri CBlood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolateJ Nutr.(2008 Sep)
    314. Cocoa Extract - Hamed MS, Gambert S, Bliden KP, Bailon O, Singla A, Antonino MJ, Hamed F, Tantry US, Gurbel PADark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot studySouth Med J.(2008 Dec)
    315. Rose Hip - Nagatomo A, Nishida N, Fukuhara I, Noro A, Kozai Y, Sato H, Matsuura YDaily intake of rosehip extract decreases abdominal visceral fat in preobese subjects: a randomized, double-blind, placebo-controlled clinical trialDiabetes Metab Syndr Obes.(2015 Mar 6)
    316. Kefir - Ghizi ACdS et alKefir improves blood parameters and reduces cardiovascular risks in patients with metabolic syndromePharmaNutrition.()
    317. Policosanol - Backes JM, Gibson CA, Ruisinger JF, Moriarty PMModified-policosanol does not reduce plasma lipoproteins in hyperlipidemic patients when used alone or in combination with statin therapyLipids.(2011 Oct)
    318. Curcumin - Mohammadi A, Sahebkar A, Iranshahi M, Amini M, Khojasteh R, Ghayour-Mobarhan M, Ferns GAEffects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trialPhytother Res.(2013 Mar)
    319. Artichoke Extract - Bundy R, Walker AF, Middleton RW, Wallis C, Simpson HCArtichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trialPhytomedicine.(2008 Sep)
    320. Hesperidin - Mohammadi M, Ramezani-Jolfaie N, Lorzadeh E, Khoshbakht Y, Salehi-Abargouei AHesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure: A systematic review and meta-analysis of randomized controlled clinical trialsPhytother Res.(2019 Mar)
    321. Guggul - Nohr LA, Rasmussen LB, Straand JResin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia? A randomized, controlled studyComplement Ther Med.(2009 Jan)
    322. Ketogenic Diet - Ranjan A, Schmidt S, Damm-Frydenberg C, Holst JJ, Madsbad S, Nørgaard KShort-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trialDiabetes Obes Metab.(2017 Oct)
    323. Coenzyme Q10 - Mohseni M, Vafa M, Zarrati M, Shidfar F, Hajimiresmail SJ, Rahimi Forushani ABeneficial Effects of Coenzyme Q10 Supplementation on Lipid Profile and Intereukin-6 and Intercellular Adhesion Molecule-1 Reduction, Preliminary Results of a Double-blind Trial in Acute Myocardial InfarctionInt J Prev Med.(2015 Aug 7)
    324. Cocoa Extract - West SG, McIntyre MD, Piotrowski MJ, Poupin N, Miller DL, Preston AG, Wagner P, Groves LF, Skulas-Ray ACEffects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adultsBr J Nutr.(2014 Feb)
    325. Olive Leaf Extract - de Bock M, Derraik JG, Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WSOlive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover TrialPLoS One.(2013)
    326. Spirulina - Szulinska M, Gibas-Dorna M, Miller-Kasprzak E, Suliburska J, Miczke A, Walczak-Gałezewska M, Stelmach-Mardas M, Walkowiak J, Bogdanski PSpirulina maxima improves insulin sensitivity, lipid profile, and total antioxidant status in obese patients with well-treated hypertension: a randomized double-blind placebo-controlled studyEur Rev Med Pharmacol Sci.(2017 May)
    327. Paleolithic Diet - C Mellberg, S Sandberg, M Ryberg, M Eriksson, S Brage, C Larsson, T Olsson, B LindahlLong-term effects of a Palaeolithic-type diet in obese postmenopausal women: a 2-year randomized trialEur J Clin Nutr.(2014 Mar)
    328. Curcumin - Rahmani S, Asgary S, Askari G, Keshvari M, Hatamipour M, Feizi A, Sahebkar ATreatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled TrialPhytother Res.(2016 Sep)
    329. Conjugated Linoleic Acid - Racine NM, Watras AC, Carrel AL, Allen DB, McVean JJ, Clark RR, O'Brien AR, O'Shea M, Scott CE, Schoeller DAEffect of conjugated linoleic acid on body fat accretion in overweight or obese childrenAm J Clin Nutr.(2010 May)
    330. DHEA - Jankowski CM, Gozansky WS, Van Pelt RE, Wolfe P, Schwartz RS, Kohrt WMOral dehydroepiandrosterone replacement in older adults: effects on central adiposity, glucose metabolism and blood lipidsClin Endocrinol (Oxf).(2011 Oct)
    331. Benfotiamine - Alkhalaf A, Klooster A, van Oeveren W, Achenbach U, Kleefstra N, Slingerland RJ, Mijnhout GS, Bilo HJ, Gans RO, Navis GJ, Bakker SJA double-blind, randomized, placebo-controlled clinical trial on benfotiamine treatment in patients with diabetic nephropathyDiabetes Care.(2010 Jul)
    332. Benfotiamine - Fraser DA, Diep LM, Hovden IA, Nilsen KB, Sveen KA, Seljeflot I, Hanssen KFThe effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trialDiabetes Care.(2012 May)
    333. TUDCA - Crosignani A, Battezzati PM, Setchell KD, Invernizzi P, Covini G, Zuin M, Podda MTauroursodeoxycholic acid for treatment of primary biliary cirrhosis. A dose-response studyDig Dis Sci.(1996 Apr)
    334. Paleolithic Diet - Mohammad Hassan Sohouli, Somaye Fatahi, Abolfazl Lari, Mojtaba Lotfi, Maryam Seifishahpar, Mihnea-Alexandru Găman, Seyedeh Tayebeh Rahideh, Saud K AlBatati, Abdullah M AlHossan, Sara A Alkhalifa, Sara A Alomar, Ahmed Abu-ZaidThe effect of paleolithic diet on glucose metabolism and lipid profile among patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trialsCrit Rev Food Sci Nutr.(2021 Jan 25)
    335. Inositol - Maeba R, Hara H, Ishikawa H, Hayashi S, Yoshimura N, Kusano J, Takeoka Y, Yasuda D, Okazaki T, Kinoshita M, Teramoto TMyo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndromeJ Nutr Sci Vitaminol (Tokyo).(2008 Jun)
    336. Artichoke Extract - P. Nazni , T. Poongodi Vijayakumar , P. Alagianambi and M. AmirthaveniHypoglycemic and Hypolipidemic Effect of Cynara Scolymus among Selected Type 2 Diabetic IndividualsPakistan Journal of Nutrition.()
    337. Vitamin D - Abolfazl Mehdizadehkashi, Samaneh Rokhgireh, Kobra Tahermanesh, Neda Eslahi, Sara Minaeian, Mansooreh SamimiThe effect of vitamin D supplementation on clinical symptoms and metabolic profiles in patients with endometriosisGynecol Endocrinol.(2021 Jan 29)
    338. Pomegranate seed oil - Yuan G, Sinclair AJ, Xu C, Li DIncorporation and metabolism of punicic acid in healthy young humansMol Nutr Food Res.(2009 Oct)
    339. Policosanol - Castaño G, Más R, Fernández JC, Fernández L, Illnait J, López EEffects of policosanol on older patients with hypertension and type II hypercholesterolaemiaDrugs R D.(2002)
    340. Black seed - Najmi A, Nasiruddin M, Khan RA, Haque SFEffect of Nigella sativa oil on various clinical and biochemical parameters of insulin resistance syndromeInt J Diabetes Dev Ctries.(2008 Jan)
    341. Red Clover Extract - Howes JB, Tran D, Brillante D, Howes LGEffects of dietary supplementation with isoflavones from red clover on ambulatory blood pressure and endothelial function in postmenopausal type 2 diabetesDiabetes Obes Metab.(2003 Sep)
    342. Conjugated Linoleic Acid - Marianne Raff, Tine Tholstrup, Samar Basu, Pernille Nonboe, Martin Tang Sørensen, Ellen Marie StraarupA diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young menJ Nutr.(2008 Mar)
    343. Curcumin - Chuengsamarn S, Rattanamongkolgul S, Phonrat B, Tungtrongchitr R, Jirawatnotai SReduction of atherogenic risk in patients with type 2 diabetes by curcuminoid extract: a randomized controlled trialJ Nutr Biochem.(2014 Feb)
    344. 16:8 Intermittent Fasting - Kelsey Gabel, Jarrad Marcell, Kate Cares, Faiza Kalam, Sofia Cienfuegos, Mark Ezpeleta, Krista A VaradyEffect of time restricted feeding on the gut microbiome in adults with obesity: A pilot studyNutr Health.(2020 Jun)
    345. Spirulina - Lee EH, Park JE, Choi YJ, Huh KB, Kim WYA randomized study to establish the effects of spirulina in type 2 diabetes mellitus patientsNutr Res Pract.(2008 Winter)
    346. Curcumin - Saeede Saadati, Behzad Hatami, Zahra Yari, Mohammad Amin Shahrbaf, Sareh Eghtesad, Asieh Mansour, Hossein Poustchi, Mehdi Hedayati, Morteza Aghajanpoor-Pasha, Amir Sadeghi, Azita HekmatdoostThe effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver diseaseEur J Clin Nutr.(2019 Mar)
    347. L-Carnitine - Bloomer RJ, Tschume LC, Smith WAGlycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjectsInt J Vitam Nutr Res.(2009 May)
    348. Fish Oil - Thusgaard M, Christensen JH, Mørn B, Andersen TS, Vige R, Arildsen H, Schmidt EB, Nielsen HEffect of fish oil (n-3 polyunsaturated fatty acids) on plasma lipids, lipoproteins and inflammatory markers in HIV-infected patients treated with antiretroviral therapy: a randomized, double-blind, placebo-controlled studyScand J Infect Dis.(2009)
    349. Red Clover Extract - Nestel P, Cehun M, Chronopoulos A, DaSilva L, Teede H, McGrath BA biochanin-enriched isoflavone from red clover lowers LDL cholesterol in menEur J Clin Nutr.(2004 Mar)
    350. Boron - Militaru C, Donoiu I, Craciun A, Scorei ID, Bulearca AM, Scorei RIOral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of lifeNutrition.(2013 Jan)
    351. Red Clover Extract - Terzic MM, Dotlic J, Maricic S, Mihailovic T, Tosic-Race BInfluence of red clover-derived isoflavones on serum lipid profile in postmenopausal womenJ Obstet Gynaecol Res.(2009 Dec)
    352. Ketogenic Diet - Sharman MJ, Gómez AL, Kraemer WJ, Volek JSVery low-carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight menJ Nutr.(2004 Apr)
    353. 16:8 Intermittent Fasting - Dorothea Kesztyüs, Petra Cermak, Markus Gulich, Tibor KesztyüsAdherence to Time-Restricted Feeding and Impact on Abdominal Obesity in Primary Care Patients: Results of a Pilot Study in a Pre-Post DesignNutrients.(2019 Nov 21)
    354. Red Clover Extract - Nestel PJ, Pomeroy S, Kay S, Komesaroff P, Behrsing J, Cameron JD, West LIsoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal womenJ Clin Endocrinol Metab.(1999 Mar)
    355. Policosanol - Mirkin A, Mas R, Martinto M, Boccanera R, Robertis A, Poudes R, Fuster A, Lastreto E, Yañez M, Irico G, McCook B, Farré AEfficacy and tolerability of policosanol in hypercholesterolemic postmenopausal womenInt J Clin Pharmacol Res.(2001)
    356. Panax Ginseng (Korean Ginseng) - Park BJ, Lee YJ, Lee HR, Jung DH, Na HY, Kim HB, Shim JYEffects of Korean Red Ginseng on Cardiovascular Risks in Subjects with Metabolic Syndrome: a Double-blind Randomized Controlled StudyKorean J Fam Med.(2012 Jul)
    357. Chia seeds - Vuksan V, Whitham D, Sievenpiper JL, Jenkins AL, Rogovik AL, Bazinet RP, Vidgen E, Hanna ASupplementation of conventional therapy with the novel grain Salba (Salvia hispanica L.) improves major and emerging cardiovascular risk factors in type 2 diabetes: results of a randomized controlled trialDiabetes Care.(2007 Nov)
    358. Policosanol - Francini-Pesenti F, Brocadello F, Beltramolli D, Nardi M, Caregaro LSugar cane policosanol failed to lower plasma cholesterol in primitive, diet-resistant hypercholesterolaemia: a double blind, controlled studyComplement Ther Med.(2008 Apr)
    359. Red Clover Extract - Howes JB, Sullivan D, Lai N, Nestel P, Pomeroy S, West L, Eden JA, Howes LGThe effects of dietary supplementation with isoflavones from red clover on the lipoprotein profiles of post menopausal women with mild to moderate hypercholesterolaemiaAtherosclerosis.(2000 Sep)
    360. Psyllium - Sartore G, Reitano R, Barison A, Magnanini P, Cosma C, Burlina S, Manzato E, Fedele D, Lapolla AThe effects of psyllium on lipoproteins in type II diabetic patientsEur J Clin Nutr.(2009 Oct)
    361. Ketogenic Diet - Noakes M, Foster PR, Keogh JB, James AP, Mamo JC, Clifton PMComparison of isocaloric very low carbohydrate/high saturated fat and high carbohydrate/low saturated fat diets on body composition and cardiovascular riskNutr Metab (Lond).(2006 Jan 11)
    362. Garlic - Steiner M, Khan AH, Holbert D, Lin RIA double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipidsAm J Clin Nutr.(1996 Dec)
    363. Chromium - Pei D, Hsieh CH, Hung YJ, Li JC, Lee CH, Kuo SWThe influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trialMetabolism.(2006 Jul)
    364. Ashwagandha - Ziegenfuss TN, Kedia AW, Sandrock JE, Raub BJ, Kerksick CM, Lopez HLEffects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR TrialNutrients.(2018 Nov 20)
    365. Spirulina - Mazokopakis EE, Starakis IK, Papadomanolaki MG, Mavroeidi NG, Ganotakis ESThe hypolipidemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population: a prospective studyJ Sci Food Agric.(2013 Jun 10)
    366. Astaxanthin - Chen JT, Kotani KEffects of Astaxanthin on Liver and Leukocyte Parameters in Healthy Climacteric Women: Preliminary DataJ Med Food.(2017 Jul)
    367. L-Carnitine - Y Liang, Y Li, J Shan, B Yu, Z HoThe effects of oral L-carnitine treatment on blood lipid metabolism and the body fat content in the diabetic patientAsia Pac J Clin Nutr.(1998 Jun)
    368. Kefir - Marie-Pierre St-Onge, Edward R Farnworth, Tony Savard, Denise Chabot, Akier Mafu, Peter J H JonesKefir consumption does not alter plasma lipid levels or cholesterol fractional synthesis rates relative to milk in hyperlipidemic men: a randomized controlled trial [ISRCTN10820810]BMC Complement Altern Med.(2002)
    369. Tribulus Terrestris - Kamenov Z, Fileva S, Kalinov K, Jannini EAEvaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trialMaturitas.(2017 May)
    370. Kefir - Ezgi Bellikci-Koyu, Banu Pınar Sarer-Yurekli, Yakut Akyon, Fadime Aydin-Kose, Cem Karagozlu, Ahmet Gokhan Ozgen, Annika Brinkmann, Andreas Nitsche, Koray Ergunay, Engin Yilmaz, Zehra BuyuktuncerEffects of Regular Kefir Consumption on Gut Microbiota in Patients with Metabolic Syndrome: A Parallel-Group, Randomized, Controlled StudyNutrients.(2019 Sep 4)
    371. Curcumin - Adibian M, Hodaei H, Nikpayam O, Sohrab G, Hekmatdoost A, Hedayati MThe effects of curcumin supplementation on high-sensitivity C-reactive protein, serum adiponectin, and lipid profile in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trialPhytother Res.(2019 May)
    372. Conjugated Linoleic Acid - Venkatramanan S, Joseph SV, Chouinard PY, Jacques H, Farnworth ER, Jones PJMilk enriched with conjugated linoleic acid fails to alter blood lipids or body composition in moderately overweight, borderline hyperlipidemic individualsJ Am Coll Nutr.(2010 Apr)
    373. OMAD And 20:4 Intermittent Fasting - B D Horne, J B Muhlestein, D L Lappé, H T May, J F Carlquist, O Galenko, K D Brunisholz, J L AndersonRandomized cross-over trial of short-term water-only fasting: metabolic and cardiovascular consequencesNutr Metab Cardiovasc Dis.(2013 Nov)
    374. Magnesium - Guerrero-Romero F, Rodríguez-Morán MMagnesium improves the beta-cell function to compensate variation of insulin sensitivity: double-blind, randomized clinical trialEur J Clin Invest.(2011 Apr)
    375. Curcumin - Cicero AFG, Sahebkar A, Fogacci F, Bove M, Giovannini M, Borghi CEffects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo-controlled clinical trialEur J Nutr.(2019 Feb 22)
    376. Tetradecyl Thioacetic Acid - Løvås K, Røst TH, Skorve J, Ulvik RJ, Gudbrandsen OA, Bohov P, Wensaas AJ, Rustan AC, Berge RK, Husebye ESTetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidationDiabetes Obes Metab.(2009 Apr)
    377. Magnesium - Mooren FC, Krüger K, Völker K, Golf SW, Wadepuhl M, Kraus AOral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trialDiabetes Obes Metab.(2011 Mar)
    378. Spirulina - Park HJ, Lee YJ, Ryu HK, Kim MH, Chung HW, Kim WYA randomized double-blind, placebo-controlled study to establish the effects of spirulina in elderly KoreansAnn Nutr Metab.(2008)
    379. Garlic - Simons LA, Balasubramaniam S, von Konigsmark M, Parfitt A, Simons J, Peters WOn the effect of garlic on plasma lipids and lipoproteins in mild hypercholesterolaemiaAtherosclerosis.(1995 Mar)
    380. Astaxanthin - Nakagawa K, Kiko T, Miyazawa T, Carpentero Burdeos G, Kimura F, Satoh A, Miyazawa TAntioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytesBr J Nutr.(2011 Jun)
    381. Ketogenic Diet - Urbain P, Strom L, Morawski L, Wehrle A, Deibert P, Bertz HImpact of a 6-week non-energy-restricted ketogenic diet on physical fitness, body composition and biochemical parameters in healthy adultsNutr Metab (Lond).(2017 Feb 20)
    382. Conjugated Linoleic Acid - Whigham LD, O'Shea M, Mohede IC, Walaski HP, Atkinson RLSafety profile of conjugated linoleic acid in a 12-month trial in obese humansFood Chem Toxicol.(2004 Oct)
    383. Astaxanthin - Tominaga K, Hongo N, Fujishita M, Takahashi Y, Adachi YProtective effects of astaxanthin on skin deteriorationJ Clin Biochem Nutr.(2017 Jul)
    384. Policosanol - Dulin MF, Hatcher LF, Sasser HC, Barringer TAPolicosanol is ineffective in the treatment of hypercholesterolemia: a randomized controlled trialAm J Clin Nutr.(2006 Dec)
    385. Maca - Meissner HO, Mscisz A, Reich-Bilinska H, Mrozikiewicz P, Bobkiewicz-Kozlowska T, Kedzia B, Lowicka A, Barchia IHormone-Balancing Effect of Pre-Gelatinized Organic Maca (Lepidium peruvianum Chacon): (III) Clinical responses of early-postmenopausal women to Maca in double blind, randomized, Placebo-controlled, crossover configuration, outpatient studyInt J Biomed Sci.(2006 Dec)
    386. Psyllium - Rodríguez-Morán M, Guerrero-Romero F, Lazcano-Burciaga GLipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetesJ Diabetes Complications.(1998 Sep-Oct)
    387. Conjugated Linoleic Acid - Laso N, Brugué E, Vidal J, Ros E, Arnaiz JA, Carné X, Vidal S, Mas S, Deulofeu R, Lafuente AEffects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome componentsBr J Nutr.(2007 Oct)
    388. Saffron - Nasim Abedimanesh, S Zahra Bathaie, Saeed Abedimanesh, Behrooz Motlagh, Ahmad Separham, Alireza OstadrahimiSaffron and crocin improved appetite, dietary intakes and body composition in patients with coronary artery diseaseJ Cardiovasc Thorac Res.(2017)
    389. Spirulina - José J van den Driessche, Jogchum Plat, Maurice C J M Konings, Ronald P MensinkEffects of spirulina and wakame consumption on intestinal cholesterol absorption and serum lipid concentrations in non-hypercholesterolemic adult men and womenEur J Nutr.(2020 Aug)
    390. Chia seeds - Nieman DC, Cayea EJ, Austin MD, Henson DA, McAnulty SR, Jin FChia seed does not promote weight loss or alter disease risk factors in overweight adultsNutr Res.(2009 Jun)
    391. Policosanol - Kassis AN, Jones PJLack of cholesterol-lowering efficacy of Cuban sugar cane policosanols in hypercholesterolemic personsAm J Clin Nutr.(2006 Nov)
    392. Hesperidin - Demonty I, Lin Y, Zebregs YE, Vermeer MA, van der Knaap HC, Jäkel M, Trautwein EAThe citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and womenJ Nutr.(2010 Sep)
    393. Potatoes - E A Johnston, K S Petersen, P M Kris-EthertonDaily intake of non-fried potato does not affect markers of glycaemia and is associated with better diet quality compared with refined grains: a randomised, crossover study in healthy adultsBr J Nutr.(2020 May 14)
    394. Policosanol - Castaño G, Mas R, Fernández L, Illnait J, Gámez R, Alvarez EEffects of policosanol 20 versus 40 mg/day in the treatment of patients with type II hypercholesterolemia: a 6-month double-blind studyInt J Clin Pharmacol Res.(2001)
    395. Curcumin - Maithili Karpaga Selvi N, Sridhar MG, Swaminathan RP, Sripradha REfficacy of Turmeric as Adjuvant Therapy in Type 2 Diabetic PatientsIndian J Clin Biochem.(2015 Apr)
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    424. Garlic - Veena Dhawan, Sanjay JainGarlic supplementation prevents oxidative DNA damage in essential hypertensionMol Cell Biochem.(2005 Jul)
    425. Boron - Scorei R, Mitrut P, Petrisor I, Scorei IA double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritisBiol Trace Elem Res.(2011 Dec)
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    427. Vitamin D - Elisabeth Lerchbaum, Christian Trummer, Verena Theiler-Schwetz, Martina Kollmann, Monika Wölfler, Annemieke C Heijboer, Stefan Pilz, Barbara Obermayer-PietschEffects of vitamin D supplementation on androgens in men with low testosterone levels: a randomized controlled trialEur J Nutr.(2019 Dec)
    428. Yacon - Genta S, Cabrera W, Habib N, Pons J, Carillo IM, Grau A, Sánchez SYacon syrup: beneficial effects on obesity and insulin resistance in humansClin Nutr.(2009 Apr)
    429. Korean black raspberry - Ji Eun Lee, Eunkyo Park, Jung Eun Lee, Joong Hyuck Auh, Hyung-Kyoon Choi, Jaehwi Lee, Soomuk Cho, Jung-Hyun KimEffects of a Rubus coreanus Miquel supplement on plasma antioxidant capacity in healthy Korean menNutr Res Pract.(2011 Oct)
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    432. HMB - Richard B. Kreider, Maria Pontes Ferreira, Michael Greenwood, M. Wilson, Pamela Grindstaff, Steven Plisk, Jeff Reinardy, Edward Cantler, and Anthony L. AmaldaEffects of Calcium β-HMB Supplementation During Training on Markers of Catabolism, Body Composition, Strength and Sprint PerformanceJournal of Exercise Physiology.()
    433. Cocoa Extract - Tokede OA, Gaziano JM, Djoussé LEffects of cocoa products/dark chocolate on serum lipids: a meta-analysisEur J Clin Nutr.(2011 Aug)
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    441. Olive Leaf Extract - Susalit E, Agus N, Effendi I, Tjandrawinata RR, Nofiarny D, Perrinjaquet-Moccetti T, Verbruggen MOlive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with CaptoprilPhytomedicine.(2011 Feb 15)
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    458. Fish Oil - Morgan WA, Raskin P, Rosenstock JA comparison of fish oil or corn oil supplements in hyperlipidemic subjects with NIDDMDiabetes Care.(1995 Jan)
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    461. Tart Cherry Juice - Desai T, Roberts M, Bottoms LEffects of short-term continuous Montmorency tart cherry juice supplementation in participants with metabolic syndrome.Eur J Nutr.(2021-Apr)
    462. Tart Cherry Juice - Rachel Kimble, Karen M Keane, John K Lodge, Glyn HowatsonThe Influence of Tart Cherry ( Prunus cerasus, cv Montmorency) Concentrate Supplementation for 3 Months on Cardiometabolic Risk Factors in Middle-Aged Adults: A Randomised, Placebo-Controlled TrialNutrients.(2021 Apr 23)
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    465. Tart Cherry Juice - Sinclair J, Bottoms L, Dillon S, Allan R, Shadwell G, Butters BEffects of Montmorency Tart Cherry and Blueberry Juice on Cardiometabolic and Other Health-Related Outcomes: A Three-Arm Placebo Randomized Controlled Trial.Int J Environ Res Public Health.(2022-Apr-27)
    466. Tart Cherry Juice - Keith R Martin, Katie M ColesConsumption of 100% Tart Cherry Juice Reduces Serum Urate in Overweight and Obese AdultsCurr Dev Nutr.(2019 Feb 25)
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    477. Tongkat Ali - Alice Erwig Leitão, Melissa de Carvalho Souza Vieira, Diogo Almeida Gomes, Leonessa Boing, Andreia Pelegrini, Edson Luiz, Adriana Coutinho de Azevedo GuimarãesExercise associated or not to the intake of Eurycoma longifolia improves strength and cardiorespiratory fitness in men with androgen deficiencyComplement Ther Clin Pract.(2021 Feb)
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    479. Zinc - Laura M Pompano, Erick BoyEffects of Dose and Duration of Zinc Interventions on Risk Factors for Type 2 Diabetes and Cardiovascular Disease: A Systematic Review and Meta-AnalysisAdv Nutr.(2020 Jul 28)
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    482. Taurine - Lin Guan, Peng MiaoThe effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trialsEur J Pharmacol.(2020 Oct 15)
    483. Berberine - Yang L, Zhu W, Zhang X, Zhou X, Wu W, Shen TEfficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials.Phytomedicine.(2023-Apr)
    484. Berberine - Osadnik T, Goławski M, Lewandowski P, Morze J, Osadnik K, Pawlas N, Lejawa M, Jakubiak GK, Mazur A, Schwingschackl L, Gąsior M, Banach MA network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults.Pharmacol Res.(2022-Sep)
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    492. Red Clover Extract - Błaszczuk A, Barańska A, Kanadys W, Malm M, Jach ME, Religioni U, Wróbel R, Herda J, Polz-Dacewicz MRole of Phytoestrogen-Rich Bioactive Substances ( L., L., L.) in Cardiovascular Disease Prevention in Postmenopausal Women: A Systematic Review and Meta-Analysis.Nutrients.(2022-Jun-14)
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    504. Alpha-Linolenic Acid (ALA) - Yin S, Xu H, Xia J, Lu Y, Xu D, Sun J, Wang Y, Liao W, Sun GEffect of Alpha-Linolenic Acid Supplementation on Cardiovascular Disease Risk Profile in Individuals with Obesity or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Adv Nutr.(2023-Sep-29)
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    520. DHEA - Qin Y, O Santos H, Khani V, Tan SC, Zhi YEffects of dehydroepiandrosterone (DHEA) supplementation on the lipid profile: A systematic review and dose-response meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis.(2020-Aug-28)
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    524. Stinging Nettle - Tabrizi R, Sekhavati E, Nowrouzi-Sohrabi P, Rezaei S, Tabari P, Ghoran SH, Jamali N, Jalali M, Moosavi M, Kolahi AA, Bettampadi D, Sahebkar A, Safiri SEffects of on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials.Mini Rev Med Chem.(2022)
    525. Coenzyme Q10 - Tianqing Zhang, Qi He, Hao Xiu, ZiZhu Zhang, Yao Liu, Zhenrong Chen, Hengjing HuEfficacy and Safety of Coenzyme Q10 Supplementation in the Treatment of Polycystic Ovary Syndrome: a Systematic Review and Meta-analysisReprod Sci.(2022 Aug 8)
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    527. Coenzyme Q10 - Shi-Ying Zhang, Kai-Lin Yang, Liu-Ting Zeng, Xiao-He Wu, Hui-Yong HuangEffectiveness of Coenzyme Q10 Supplementation for Type 2 Diabetes Mellitus: A Systematic Review and Meta-AnalysisInt J Endocrinol.(2018 Sep 16)
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    532. Docosahexaenoic Acid - Wei MY, Jacobson TAEffects of eicosapentaenoic acid versus docosahexaenoic acid on serum lipids: a systematic review and meta-analysisCurr Atheroscler Rep.(2011 Dec)
    533. Spirulina - Hatami E, Ghalishourani SS, Najafgholizadeh A, Pourmasoumi M, Hadi A, Clark CCT, Assaroudi M, Salehi-Sahlabadi A, Joukar F, Mansour-Ghanaei FThe effect of spirulina on type 2 diabetes: a systematic review and meta-analysis.J Diabetes Metab Disord.(2021-Jun)
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    555. Chlorella - Ding KX, Gao TL, Xu R, Cai J, Zhang HQ, Sun YY, Zhong F, Ma AGQuantifying the Effect of Supplementation with Algae and Its Extracts on Glycolipid Metabolism: A Meta-Analysis of Randomized Controlled Trials.Nutrients.(2020-Jun-08)
    556. Chlorella - Fallah AA, Sarmast E, Habibian Dehkordi S, Engardeh J, Mahmoodnia L, Khaledifar A, Jafari TEffect of Chlorella supplementation on cardiovascular risk factors: A meta-analysis of randomized controlled trials.Clin Nutr.(2018-Dec)
    557. Chlorella - Sherafati N, Bideshki MV, Behzadi M, Mobarak S, Asadi M, Sadeghi OEffect of supplementation with Chlorella vulgaris on lipid profile in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.Complement Ther Med.(2022-Jun)
    558. Black seed - Jamal Hallajzadeh, Alireza Milajerdi, Moein Mobini, Elaheh Amirani, Susan Azizi, Elhameh Nikkhah, Babak Bahadori, Razieh Sheikhsoleimani, Seyyed Mehdi MirhashemiEffects of Nigella sativa on glycemic control, lipid profiles, and biomarkers of inflammatory and oxidative stress: A systematic review and meta-analysis of randomized controlled clinical trialsPhytother Res.(2020 Oct)
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    561. Panax Ginseng (Korean Ginseng) - Effects of Panax ginseng on hyperglycemia, hypertension, and hyperlipidemia: A systematic review and meta-analysis.()
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    565. Saffron - Amatto PPG, Chaves L, Braga GG, Carmona F, Pereira AMSEffect of Crocus sativus L. (saffron) and crocin in the treatment of patients with type-2 diabetes mellitus: A systematic review and meta-analysis.J Ethnopharmacol.(2023-Sep-29)
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    569. Dill - Mousavi SM, Beatriz Pizarro A, Akhgarjand C, Bagheri A, Persad E, Karimi E, Wong A, Jayedi AThe effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials.Crit Rev Food Sci Nutr.(2022)
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    576. Ketogenic Diet - Parry-Strong A, Wright-McNaughton M, Weatherall M, Hall RM, Coppell KJ, Barthow C, Krebs JDVery low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials.Diabetes Obes Metab.(2022-Dec)
    577. Ketogenic Diet - Choy KYC, Louie JCYThe effects of the ketogenic diet for the management of type 2 diabetes mellitus: A systematic review and meta-analysis of recent studies.Diabetes Metab Syndr.(2023-Dec)
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    581. Dietary Approaches to Stop Hypertension (DASH) Diet - Ru Guo, Nian Li, Rong Yang, Xiao-Yang Liao, Yu Zhang, Ben-Fu Zhu, Qian Zhao, Lingmin Chen, Yong-Gang Zhang, Yi LeiEffects of the Modified DASH Diet on Adults With Elevated Blood Pressure or Hypertension: A Systematic Review and Meta-AnalysisFront Nutr.(2021 Sep 7)
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    586. Psyllium - Wei ZH, Wang H, Chen XY, Wang BS, Rong ZX, Wang BS, Su BH, Chen HZTime- and dose-dependent effect of psyllium on serum lipids in mild-to-moderate hypercholesterolemia: a meta-analysis of controlled clinical trials.Eur J Clin Nutr.(2009 Jul)
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